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  1. Licensing and Collaboration Opportunities

FDA Technologies Available for Licensing and Collaboration

Title E # Product Area Research Area Technologies & Applications Development Stage FY Keywords
Nonpathogenic Bacteria, Paenibacillus alvei, Useful As a Natural Biocontrol Agent for Elimination of Food-Borne Pathogenic Bacteria E-2014-007 Drugs Bacterial Infectious Disease, Antimicrobial Therapeutics, drug design in vitro 2014 antimicrobial, peptides, bacterial, infectious disease, salmonela, paenibacillus alvei, bactericide
Serum-free Medium for In Vitro Isolation and Expansion of Canine Adipose-Derived Mesenchymal Stem/Stromal Cells (MSCs) E-2017-010 Animal & Veterinary   Bioassays   2017 serum, serum-free, medium, media, stem, stromal, expansion, adipose, veterinary, culture, mesenchymal, devireddy

Lentiviral vectors bearing il-13 that Target Human IL-13 Receptor alpha-2-Positive TUMOR Cells

E-2019-024 Biologics Research materials; Lentivirals Bioassay, Diagnostics, Vaccine
Hybridomas Secreting Novel Monoclonal Antibodies Against the Nucleoprotein of Influenza Virus E-2018-007 Biologics Viral Infectious Disease Bioassay, Diagnostics, Vaccine Research Reagent 2018 Influenza; Antibody; Vaccine; Diagnotic; Hongquan Wan
An Attenuated Live Mumps Virus Vaccine Candidate Expressing F and HN Protein Genes from Genotype G E-2018-022 Biologics Viral Infectious Disease Vaccines In vivo
animal data
2018 mumps, vaccine, immunity, disease, meningitis, virus, plasmid, strains, Rubin, gene, Jeryl Lynn, protein, genotype, recombinant, combination
Synergistic Antitumor Activity of Combination Immunotherapy IL-4 receptor targeted agents and Interferons -alpha and -gamma E-2017-025 Drugs, Oncology Oncology
in vivo mouse studies
2017 IL-4, interferon, puri, synergistic, ovarian, cancer, chimeric protein, pseudomonas exotoxin, IFNgamma, anti-interleukin, anti-interleukin-4, Husain, GrSynergistic Antitumor Activity of Combination Immunotherapy IL-4 receptor targeted agents and Interferons -alpha and -gamma ​
Gonoccoccal Vaccine/Therapy from Neisseria meningitidis E-2017-006 Biologics Viral infectious Diseases, bacterial infectious diseases
Vaccines, Drug Design In vivo studies 2017 meningitis, meningitidis,
Reassortant Influenza Viruses Expressing Neuraminidase (NA) And A Mismatched Hemagglutinin (HA) Protein Useful for Determining Antibody Titers of Functional Na-Specific Antibodies E-2017-022 Biologics Viral Infectious Diseases Vaccines, Diagnostics, Therapeutics   2017  
Hemoglobin-Polymer Phantoms for Biophotonic Device Performance Evaluation E-2016-002 Devices
Medical Devices  
Imaging, Medical device
Prototype 2016 hemoglobin polymer phantoms, biophotonic, device, imaging systems
Tissue-mimicking polymer test phantoms for optical-acoustic medical imaging. E-2016-003 Devices   Imaging, Medical Device Prototype 2016 Photoacoustic, imaging, phantom, optical, acoustic, tunable, magnetic, tomography, diagnostic, sound, pfefer, tissue, mimic
Anti-influenza monoclonal antibodies to hemagglutinin (HA) that are suitable for identification and quantification of seasonal influenza vaccines. E-2016-004 Biologics Viral Infectious Diseases Bioassay, Diagnostics, Vaccine In vitro data 2016 influenza, monoclonal, antibodies, glycoprotein, strain, epidemic, hemagglutinin, protein, pandemic, virus, vaccine, weir, H1N1, vaccination, diagnostic, assay
Solid-phase Purification of Synthetic DNA Sequences E-2016-005 Drugs Chemicals, Pesticides, & Metals Cellular and gene therapy, therapeutics, drug delivery In vitro data 2016 solid-phase, purification, synthetic, DNA, sequence, high-throughput, method, design, purity, technique, nucleotide, manufacture, beaucage
Therapeutic and Prophylactic Anti-Influenza Virus Neuraminidase 1 (N1) Antibody (Cd6) With a Novel Epitope That Spans Neuraminidase (Na) Dimers E-2015-001 Biologics Viral Infectious Disease Vaccines, Diagnostics, Bioassays

in vitro and in vivo

2015 CD6, neutralizing antibody, neuraminidase, hemegglutinin, influenza virus, viral
Non-Coring Needles for Elimination of Dangerous Coring E-2015-011 Medical device Non-puncture coring needles, healthcare, syringe   prototype 2015 Needle tip design, syringe, non-coring puncture needle
Use of Nonpathogenic Bacteria, Paenibacillus Alvei, as a Natural Biocontrol Agent for Elimination of Food-Borne Pathogenic Bacteria E-2011-003 Food Food Safety, Chemicals, Pesticides, & Metals Therapeutics, drug design Pre-development 2011 TS-15, food, borne, pathogens, Salmonella, Escherichia, Listeria, Shigella, Enterobacter, Staphylococcus, food supply, biocontrol, agent, pesticide, fruits, vegetable, food-borne, pathogen, antibiotic, resistant, Agriculture, Brown, Zhang
Nanoparticulate Complex of Nicotine and Cerium Oxide for the Treatment of Parkinson’s Disease E-2014-002 Drugs Neuroscience & Pain Nanotechnology In vitro data 2014 tobacco, Parkinson's, nicotine, conjugate, nanoceria, anti-oxidant, oxidant, neuronal, Imam
Vaccine for Protection Against Shigella sonnei Disease E-210-2001/0 Biologics Bacterial Infectious Diseases Vaccines, Diagnostics In vivo animal data 2001 Shigellosis, food, water, bacterium, Shigella, sonnei, antibiotics, resistant, vaccine, Shigellae, polysaccharide, immunoprotective, vaccine, mice, Shigella, Typhoid, Kopecko, Xu, Cisar
Typhoid-Plague Bivalent Vaccine E-105-2011/0 Biologics Bacterial Infectious Diseases Vaccines, Diagnostics, Therapeutics   2011 Yersinia, pestis, plague, flea, lungs, pneumonic, bioterrorist, vaccine, oral, construct, fusion, attenuated, typhoid, fever, bacterial, immune, anthrax, delivery, therapeutics, diagnostics, Vector, Kopecko, Osorio, Foote
DNA Promoters and Anthrax Vaccines E-344-2003/1 Biologics Bacterial Infectious Diseases Vaccines, Diagnostics, Therapeutics In vivo animal data 2003 vaccine, anthrax, injectable, anthracis, Escherichia, coli, alpha, hemolysin, typhoid, Salmonella, enterica, serovar, Typhi, Immunization, mice, serum, immunoglobulin, toxin, neutralizing, Vaccinated, intranasal, aerosolized, spores, Anthrax, Kopecko, Osorio, Giri, Blake, Bhattacharyya
Live Oral Shigella dysenteriae Vaccine E-2004-022 Biologics Bacterial Infectious Diseases, Food Safety Vaccines, Diagnostics, Therapeutics in vivo 2004 Salmonella, typhi, construct, Shigella, dysenteriae, polysaccharide, Ty21a, constructs, immune, dysentery, serotypes, dysentery, shigellosis, Kopecko, Xu
Oral Shigellosis Vaccine E-2012-016 Biologics Bacterial Infectious Diseases, Food Safety Vaccines, Diagnostics, Therapeutics   2012 Salmonella, typhi, Shigella, sonnei, biosynthetic, constructs, immune, antigenic, bacterial, Bacillary, dysentery, enteric, fever, dysentery, vaccine, resistance, multivalent, Shigellosis, Dharmasena, Kopecko
Synthetic Peptides with Antimicrobial Activity E-2012-023 Biologics Bacterial Infectious Diseases Therapeutics, Diagnostics In vitro data 2012 synthetic, peptides, antimicrobial, E., coli, aeruginosa, S. aureus, S. epidermidis, B. cereus, K. pneumonia, platelets, plasma, cytotoxic, blood, toxicity, drug, development, resistant, bacterial, antimicrobial, Atreya, Rao, Ketha
Software for 3D Spectral Fingerprint Based Consensus Modeling Using Orthogonal PLS and Tanimoto Similarity KNN Techniques E-015-2014/0 Drugs   Drug Design, Software/Algorithms*, Therapeutics, Drug Delivery In vitro data 2014 software, tool, molecular, modeling, data, Tanimoto, Similarity, algorithm, PLS, KNN, 3D, SDAR, Drug, design, development, Beger, Wilkes, Slavov, Buzatu, Pearce
Respiratory Syncytial Virus (RSV) Vaccine Candidates from RSV Glycoprotein (G) and Fusion (F) Protein E-2013-016,
Biologics Viral Infectious Diseases Vaccines In vitro data 2013, 2015, 2018 cross, neutralizing, vaccine, human, respiratory, syncytial, viru, immunogenic, recombinant, vaccines, immunogenicity, Khurana, Golding
Software for Evaluating Drug Induced Hepatotoxicity E-103-2012/0 Drugs Hepatology Software/Algorithms*   2012 software, tool, medical, diagnosis, drug-induced liver, injury, hepatotoxicity, Guo
Use of Cysteamine to Treat Metastatic Cancer E-219-2013/0 Drugs Oncology, Neuroscience & Pain Therapeutics In vivo animal data 2013 Cysteamine, aminothiol, anti-oxidant, radiation, neurological, cancer, matrix, metalloproteinases, MMP, tumor, metastasis, metastasis, xenograft, umor, mice, therapeutic, Puri, Joshi
Therapeutic Hepatitis C Virus Antibodies E-2012-002 Biologics Viral Infectious Diseases, Hepatology Therapeutics In vitro data 2012 Therapeutic, antibodies, Hepatitis, Virus, HCV, interfering, neutralizing, infection, monoclonal, liver, transplants, Feinstone, Duan, Major, Zhang, Kachko
Live Attenuated Rubella Vector to Express Vaccine Antigens E-004-2012/0 Biologics Viral Infectious Diseases Vaccines, Diagnostics, Therapeutics In vivo animal data 2012 Live, attenuated, viruses, HIV, vaccine, rubella, SIV, antigen, rhesus, macaques, in vivo, Bivalent, Berkower, Virnik
Multivalent Meningiococcal Conjugates and Methods for Preparing Conjugates E-082-2012/0 Biologics Bacterial Infectious Diseases Vaccines   2012 meningococcal, polysaccharide, vaccines, tetravalent, PS, tetravalent, conjugate, meningococcal, Neisseria, meningitidis, immunogen, vaccine, autoimmune, immunogenic, conjugates, polysaccharide, Neisserial, Lee, Pinto
Nanoparticle Probes and Mid-Infrared Chemical Imaging for DNA Microarray Detection E-2010-015 Biologics, Food Environmental Science Imaging, Nanotechnology, Diagnostics, Biomarkers   2010 microarray, visualization, infrared, chemical, imaging, IRCI, nanostructure, DNA, microarray, gene, expression, single, nucleotide, polymorphisms, SNPs, genome, signal-to-noise, SNR, hybridized, microarrayed, fluorescence, pathogenic, fluorescent, microarrays, protein, tissue, biochemical, chemical, toxicogenomics, microarray, Mossoba, Al-Khaldi, Schoen
Filovirus Vaccines and Diagnostics Based on Glycoprotein-Fc Fusion Proteins E-2010-018 Biologics Viral Infectious Diseases Vaccines, Diagnostics In vivo animal data 2010 Ebola, virus, Filoviridae, bioterrorism, hemorrhagic, fever, primates, Filovirus, subunit, vaccine, extracellular, glycoprotein, immunoglobulin, humoral, cellular, immunity, Vesicular, Stomatitis, Virus, response, Vaccine, virus-like particles, Kaplan, Konduru, Bavari, Bradfute
Novel Infrared (IR)-Transparent Hydrophilic Membrane That Can be Used for Filtration, Printing or Microarrays, and Cultivation of Bacteria and Other Microorganisms for Reagent-Free IR Spectroscopic Identification E-174-2005/0 Devices Bacterial Infectious Diseases Imaging, Bioassays, Diagnostics   2005 infrared, IR, transparent, microporous, plasma, polyethylene, hydrophilic, membrane, bacterial, micoorganism, impurities, food, spectroscopy, microarray, printing, food, borne, pathogens, sakazakii, pneumonia, microspectroscopy, multivariate, pathogen, screening, spores, airborne, Mossoba, Al-Khaldi
Purified Saxitoxin for Food Safety Applications E-278-2009/0 Food Natural Toxins, Food Safety Biomarkers, Bioassays   2009 Saxitoxin, toxins, seafood, food, borne, illness, Monitoring, contamination, Detection, poisons, Hall
Peptides for HIV-1 Infection Detection Assay for Seroconverted HIV-1 Vaccine Recipients E-259-2004/2 Biologics Viral Infectious Diseases Bioassays   2004  
Internal Control Nucleic Acid Molecule for Real-Time Polymerase Chain Reaction E-213-2003/0 Biologics, Food, Devices   Diagnostics, Bioassays   2003 PCR, internal, control, system, real, time, PCR, kinetic, Q-PCR, conventional, assay, Vickery, DePaola, Blackstone
Direct Impact Spark Ionization (DISI) Mass Spectrometry (MS) for Identification of Microbes E-258-2011/0 Devices Food Safety, Environmental Science Monitoring, Biodefense   2011 mass, spectrometry, device, direct, impact, spark, ionization, microbial, analytes, identification, pectral, pattern, recognition, microbiological, pathogen, determination, drugs, food, cosmetic, ingredients, monitoring, airborne, Biological, Warfare, Agents, Pathogen, bacterial, Wilkes, Alusta, Dorey, Parker, Buzatu
Bacterially Expressed Influenza Virus Recombinant HA Proteins for Vaccine and Diagnostic Applications E-032-2010/1 Biologics Viral Infectious Diseases Vaccines, Diagnostics   2010 H1N1, influenza, virus, Avian, pandemic, chicken, egg, HA, H1N1, H5N1, neutralizing, antibody, in vivo, animal , models, vaccine, diagnostic, Golding, Khurana
Novel Methods for the Reversible Incorporation of Functional Groups into RNA and DNA: Synthesis and Uses for 2'-O-aminooxymethyl Nucleoside Derivatives E-262-2010/0 Drugs, Biologics   Diagnostics, Cellular & Gene Therapy, Drug Delivery, Small Molecule Therapeutics, Drug Design   2010 DNA, RNA, therapeutic, drugs, silencing, expression, genes, interference, synthetic, synthesis, oligonucleotides, diagnostic, therapeutic, Beaucage, Cieslak
Live-Attenuated West Nile Virus Vaccines with Improved Immune Responses E-022-2004/0 Biologics Viral Infectious Diseases Vaccines   2004 West, Nile, virus, WNV, fever , encephalitis, veterinary, pathogen, vaccine, chimeric, live, attenuated, therapeutics, diagnostics, Markoff, Yu-teh
Alleviating Symptoms of Th2-Like Cytokine Mediated Disorders by Reducing IL-13 Receptor-Expressing Cells in the Respiratory Tract E-296-2001/0 Biologics Immunotherapy, Pulmonary, Viral Infectious Diseases, Bacterial Infectious Diseases, Fungal & Parasitic Infectious Diseases Therapeutics, Drug Design In vivo animal data 2001 Th2-like, cytokine, mediated, allergy, asthma, hyperinflammatory, respiratory, tract, infectious, diseases, parasitic, infections, tuberculosis, schistosomiasis, leishmania, filariasis, chimeric, IL-13, Puri
Method of Treating and Preventing Infections in Immunocompromised Subjects with Immunostimulatory CpG Oligonucleotides E-153-2002/0 Biologics Immunotherapy, Viral Infectious Diseases Cellular & Gene Therapy, Vaccines   2002 immune, humoral , cellular , phagocytes, immunodeficiency, immunosuppressive, chemotherapeutic, enteropathy, human, immunodeficiency, virus, HIV, immunocompromised, vaccine, pneumonia, Opportunistic, infections, salmonellosis, syphilis, neurosyphilis, tuberculosis, TB, mycobacterial, angiomatosis, fungal, aspergillosis, candidiasis, thrush, yeast, infection, coccidioidomycosis, cryptococcal, meningitis, histoplasmosis, protozoal, cryptosporidiosis, isosporiasis, microsporidiosis, Pneumocystis, Carinii , PCP, toxoplasmosis, viral, Cytomegalovirus, CMV, hepatitis, herpes, simplex, HSV, genital, herpes, herpes, zoster, HZV, shingles, human, papilloma, virus, HPV, genital, warts, cervical, cancer, Molluscum, Contagiosum, oral, hairy, leukoplakia, OHL, progressive, multifocal, leukoencephalopathy, PML, neoplasms, Kaposi's, sarcoma, non-Hodgkin's, lymphoma, NHL, primary, CNS, lymphoma, immunostimulatory, CpG, oligonucleotides , Vaccine, adjuvants, production, immunotherapeutics, Klinman, Verthelyi
Meningococcal and Pneumococcal Conjugate Vaccine and Method of Using Same E-030-2010/0 Biologics Bacterial Infectious Diseases Vaccines   2010 Pneumococcal, Streptococcus, pneumoniae, pneumonia, meningitis, febrile, bacteremia, otitis, media, sinusitis, bronchitis, Vaccination, microbial resistance, bacterial, meningococcus, Neisseria, meningitidis, respiratory, meningeal, septic, pneumonia, meningitis, vaccine, pathogen, conjugate, vaccines, recombinant, Lee
LightCensor: Software for Optimizing Lighting for Viewing of Medical Images E-284-2010/0 Devices   Imaging, Software/Algorithms*   2010 algorithm, mobile device, smartphone, medical, imaging, hand-held, device, mobile, Biomedical, Radiology, Cheng
System for Magnetic Resonance Spectroscopy of Brain Tissue for Pattern-based Diagnostics E-2009-011 Devices Neuroscience & Pain Medical Devices, Imaging   2009 Magnetic, resonance, spectroscopy, MRS, Brain, Tissue, Pattern, Based, Diagnostic, Preprocessing, Module, Spectrum, Normalize, Scan, Raw, MRI, Brain, Imaging, Neurology, Wilkes, Buzatu, Alusta, Pearce, Kretzer, Im, Beger
Insertion of Foreign Genes in Rubella Virus and their Stable Expression in a Live, Attenuated Viral Vaccine E-156-2008/0 Biologics Viral Infectious Diseases Vaccines   2008 Rubella, virus, RUB, Rubivirus, Togaviridae, genes, vector, live, vaccine, HIV, vector, expression, Berkower, Spadaccini
A Hand Held Portable Device Based on LEDS for Use in The Detection of Counterfeit Pharmaceutical Drugs and Packaging E-2008-017 Devices, Drugs   Post-Market Surveillance, Monitoring Prototype 2008 hand, held, portable, device, detection, counterfeited, pharmaceutical, prototype, light, emitting, diode, LED, Testing, authenticity, Ranieri
Novel Oligonucleotides for Treatment of Human Cancer E-092-2008/0 Drugs, Biologics Oncology Therapeutics, Cellular & Gene Therapy   2008 Human, endogenous, retroviruses, HERV, antisense, sense, oligonucleotides, RNA, ERV-9, LTR, cancer, breast, liver, prostate, myeloid, fibrosarcoma, therapeutic, tumor, siRNA, gene, expression, Therapeutic, Xu, Rosenberg, Elkahloun, Candotti
Controlled Formation of CpG Oligonucleotide Multimers E-2004-024 Drugs, Biologics Adjuvants; Vaccines; Oligonucleotide Therapeutics Drug design; Cellular and gene therapies; Molecule delivery in vitro data; in vivo data; preclinical primate studies 2004 CpG, oligonucleotides, oligonucleotide, prodrug, Therapeutic, immune, immunostimulatory, Verthelyi, Beaucage, Grajkowski
Use of Sterically Stabilized Cationic Liposomes to Efficiently Deliver CpG Oligonucleotides in vivo E-215-2001/0 Drugs Immunotherapy Drug Delivery, Drug Design, Cellular & Gene Therapy In vitro data, In vivo animal data 2001 Immunostimulatory, CpG, oligonucleotide, ODN, immune, adjuvant, anti-allergens, Sterically, Stabilized, Cationic, Liposomes, SSCL, in vivo, in vitro, mice, L. monocytogenes, listeria, Klinman, Gursel
Identification of DNA Sequence Motifs that Suppress the Immune Response to CpG DNA E-218-2001/0 Drugs Immunotherapy Cellular & Gene Therapy   2001 CpG, oligonucleotide, immunostimulatory, oligodeoxynucleotides, ODN, septic, shock, adult, respiratory, distress, syndrome, ARDS, autoimmune, disease, suppressive, vaccine, therapeutic, Klinman, Gursel
Monoclonal Antibodies to Fusion-Active Conformations of HIV-gp41 E-2007-011 Biologics Viral Infectious Diseases Bioassays, Therapeutics   2007 monoclonal, HIV, gp41, tool, screening, antiretroviral, Research, Weiss, Vassell
Diagnostic Targets and Potential Vaccine Against H5N1 Avian Influenza E-2007-026 Biologics Viral Infectious Diseases Therapeutics, Vaccines in vivo studies 2007 peptide, polypeptide, influenza, virus , immunogenic, neutralizing, antibodies, avian, H1N1, H3N2, H5N1, H7N7, immunogenic, adjuvant, vaccine, Diagnostic, Golding, Khurana
Oligodeoxynucleotide and Its Use To Induce an Immune Response E-147-1999/0 Biologics Oncology, Immunotherapy Cellular & Gene Therapy, Vaccines   1999 oligodeoxynucleotides, ODN, CpG, immunostimulatory, immune, production, T cell, therapeutic, cancer, vaccine, adjuvant, autoimmune, disorders, immune, deficiencies, anti-infective, antisense, therapy, Klinman, Verthelyi, Ishii, Gursel
Use Of Calreticulin And Calreticulin Fragments To Inhibit Endothelial Cell Growth And Angiogenesis, And Suppress Tumor Growth E-082-1998/0 Biologics Oncology Therapeutics   1998 Tumor, EBV, immortalized, Burkitt's, lymphoma, colon, carcinoma, vascular, angiogenesis, vasostatin, calreticulin, endothelial, proliferation, neovascularization, antitumor, Tosato, Pike, Yao
Neutralization of Hepatitis C Virus (HCV) E-276-2007/1   Viral Infectious Diseases Therapeutics   2007  
Improved Immunotherapeutic Compositions for Treatment, Diagnosis and Prevention of HIV E-2008-027 Biologics Viral Infectious Diseases Therapeutics, Vaccines, Diognostics   2008 HIV, vaccine, neutralizing, antibodies, glycoprotein, immune, immunization, gp120, immunogen, polypeptide, virus-like, particles, TLR, therapeutics, diagnostics, Berkower
Mouse Monoclonal Antibody Targeting Tetanus Toxin Heavy Chain Fragment C E-061-2009/0 Biologics Bacterial Infectious Diseases, Natural Toxins Therapeutics   2009 murine, monoclonal, antibody, tetanus, toxin, neurotoxin, neuron, botulinum, antitoxins, Shapiro, Fitzsimmons
Membrane Proximal Region of HIV gp41 Anchored to the Lipid Layer of a Virus-Like Particle Vaccine E-291-2008/0 Biologics Viral Infectious Diseases Therapeutics, Vaccines, Diognostics   2008 HIV, envelope, glycoprotein, gp120, gp41, immunogenic, antibodies, immune, membrane, proximal, region, MPR, hepatitis, surface, antigen, HBsAg, epitope, Human , Immunodeficiency , Virus, vaccine, therapeutic, diagnostic, Berkower
Compounds Used to Improve Human Immune Responses in Diseases such as Allergies, Infections, and Cancer E-078-2000/1 Drugs Immunotherapy, Oncology, Viral Infectious Diseases, Bacterial Infectious Diseases,
Fungal & Parasitic Infectious Diseases
Cellular & Gene Therapy, Vaccines, Drug Design   2000 immune, oligonucleotide, CpG, therapeutic, immunomodulatory, humoral, cell-mediated, allergies, infectious, diseases, cancer, autoimmune, vaccine, adjuvant, DNA, anti-sense, Klinman, Verthelyi, Ishii
A Method with Increased Yield for Production of Polysaccharide-Protein Conjugate Vaccines Using Hydrazide Chemistry E-301-2003/0 Biologics Viral Infectious Diseases, Bacterial Infectious Diseases Vaccines, Drug Design   2003 synthesis, manufacturing, polysaccharide, conjugate, vaccine, conjugation, PS, hydrazide, manufacturing, conjugate, Lee, Frasch
Method of Treating Infectious and Inflammatory Lung Disease with Suppressive Oligonucleotides E-183-2002/0 Drugs, Biologics Pulmonary, Immunotherapy Cellular & Gene Therapy, Vaccines   2002 Lung, chronic, inflammatory, lung, emphysema, chronic, bronchitis, acute, respiratory, distress, syndrome, ARDS, inflammation, suppressive, oligonucleotide, pneumonia, Vaccine, adjuvant, production, immunotherapeutics, Klinman, Yamada
Methods for Preparing Complex Multivalent Immunogenic Conjugates E-085-2005/0 Biologics Viral Infectious Diseases, Bacterial Infectious Diseases Vaccines, Drug Design   2005 multivalent, immunogenic, conjugates, conjugate, vaccine, polysaccharide, hydrazide, conjugation, Lee
Monoclonal Antibodies Against Bordetella pertussis Filamentous Hemagglutinin (FHA) Protein E-044-2008/0 Biologics Bacterial Infectious Diseases Vaccines, Therapeutics, Diognostics   2008  
Identification of a Cell-Surface Co-Receptor that Mediates the Uptake and Immunostimulatory Activity of "D" Type CpG Oligonucleotides E-036-2005/0 Drugs, Biologics Immunotherapy Cellular & Gene Therapy, Vaccines, Drug Delivery   2005 CpG, immune, proinflammatory, oligonucleotides, scavenger receptor, immune, Vaccine, adjuvant, production, immunotherapeutics, Klinman, Gursel
Polypeptides for Eliciting Neutralizing Antibodies Against HIV E-212-2001/0 Biologics Viral Infectious Diseases Vaccines, Therapeutics   2001 antibody, response, HIV, gp41, vaccine, Neutralizing, antibodies, Weiss
Citrobacter freundii WR7011 as a Vaccine Strain or Source of Vi Capsular Antigen for Protection Against Typhoid Fever E-004-2007/0 Biologics Bacterial Infectious Diseases, Food Safety Vaccines   2007 typhoid, fever, Vi, typhi, Citrobacter, freundii, WR7004, polysaccharide, nonpathogenic, production, vaccine, manufacture, Kopecko, Xu, Research, Tool
Measles Virus Strain for Diagnostic Applications E-125-2007/0 Biologics Viral Infectious Diseases Vaccines, Therapeutics, Diognostics   2007 Edmonston, strain, measles, neutralizing antibody, therapeutic, accine, diagnostic, Albrecht, Beeler, Audet, Farrell, Burns, Research, Tool
Human and Avian Influenza Whole Genome Phage Display Libraries E-031-2007/0 Biologics, Animal & Veterinary Viral Infectious Diseases Vaccines, Diagnostics   2007 reagents, therapeutics, diagnostics, bacteriophage, display, libraries, influenza, viral, gene, pandemic, influenza, vaccine, pandemic, Whole, Viral, Genome, Phage, Display, Libraries, Avian, HlN1, H3N2, H5N1, H7N7, Serological, assay, surveillance, immune, monoclonal, polyclonal, antibodies, epitope, Golding, Khurana, Research Tool
Hollow Waveguide Laser Delivery System for Digital Particle Image Velocity E-015-2006/0 Devices   Imaging   2006 laser, delivery, system, digital, particle, image, velocimetry, DPIV, illumination, Optics, Ilev, Robinson, Waynant
Imaging with Positron-Emitting Taxanes, Camptothecins, and Other Drugs as a Guide to Antitumor Therapy E-263-1998/0 Drugs Oncology Monitoring, Imaging, Drug Delivery   1998 positron, emitting, taxane, synthesis, probe, 11C-SN-38, 11C-imatinib, 11C-mitoxantrone, SN-38, Camptosar, colorectal, Imatinib, chronic, myeloid, leukemia, CML, Gleevec, Mitoxantrone, cancer, multiple, sclerosis, tumor, Collins, Klecker, Anderson
Confocal Fiber-Optic Laser Method for Intraocular Lens Power Measurement E-2005-007 Devices Ophthalmology Medical Devices   2005 fiber, optic, laser, confocal, Intraocular, lens, IOL, dioptic, power, measurement, single-mode, optical, Ilev
Ultrahigh-Resolution Fiber-Optic Confocal Microscope And Method E-038-2005/0 Devices   Medical Devices   2005 single, mode, fiber, optic, confocal, microscope, ultrahigh, resolution, illumination, Ilev, Waynant, Gannot, Gandjbakhche
Monoclonal Antibody 90.12 Recognizes a Novel B Cell Surface Antigen Upregulated on Both Activated and Apoptotic Lymphocytes E-195-2004/0 Biologics Oncology Therapeutics   2004 Monoclonal, antibody, calcium, binding, proteins, Shapiro
Thermolytic Hydroxyl-Protecting Groups for Improved Oligonucleotide Synthesis E-2003-008 Biologics, Drugs Gene therapy Vaccines, Cellular & Gene Therapy, Drug Design, Diagnostics, Bioassays, Monitoring   2003 Synthetic, oligonucleotide, gene, therapy, diagnostic, DNA, sequencing, microarray, glass, synthesis, Beaucage, Chmielewski
Methods for Predicting Properties of Molecules E-297-2001/0 Devices       2001 chemical, shift, data, spatial, distance, connectivity, patterns, NMR, spectral, cancer, drug, three dimensional, Quantitative, Structure, Data, Activity, Relationship, QSDAR, Beger, Wilkes
Use of CpG Oligodeoxynucleotides to Encourage Angiogenesis E-328-2001/0 Biologics, Drugs Oncology Cellular & Gene Therapy   2001 angiogenesis, CpG, oligonucleotide, tumor, atherogenesis, arthritis, corneal, neovascularization, diabetic, retinopathy, wound, healing, malignancies, oligodeoxynucleotide, ODN, vaccine, adjuvant, anti-allergens, immune, central, nervous, system, cornea, VEGF, Vascular, Endothelial, Growth, Factor, Klinman
Microbial Identification Databases E-169-2000/1 Food, Biologics, Drugs, Animal & Veterinary Viral Infectious Diseases, Bacterial Infectious Diseases, Fungal & Parasitic Infectious Diseases, Food Safety, Environmental Science Monitoring, Post-Market Surveillance, Biodefense   2000 database, pyrolysis, mass, spectra, chemotaxonomy, microbial, MALDI, infrared, chromatogram, NMR, ion, mobility, microorganism, pathogen, Wilkes
Novel Method for Rapidly Generating Mature Dendritic Cells from Peripheral Blood Monocytes and Myeloid Precursors E-214-2001/0 Biologics, Drugs Immunotherapy Cellular & Gene Therapy, Therapeutics   2001 CpG, oligodeoxynucleotide, ODN, dendritic, DC, cytokines, chemokines, monocytes, dendritic, immune, cancer, infectious, disease, Klinman, Gursel, Verthelyi
Method for Non-Invasive Identification of Individuals at Risk for Diabetes E-091-1998/0 Devices Endocrinology & Metabolic Diseases Diagnostics   1998 non, invasive, ocular, diabetes, Raman, spectra, eye, laser, diagnose, predict, Durkin, Ediger, Chenault
N-Acylphosphoramidites And Their Use In Oligonucleotide Synthesis E-031-1998/0 Biologics   Cellular & Gene Therapy, Therapeutics, Diagnostics   1998 synthesis, oligonucleotide, therapeutic, antisense, nucleic, acids, messenger, RNA, Beaucage, Wilk, Grajkowski