List of Pregnancy Exposure Registries
From the FDA Office of Women's Health
Pregnancy exposure registries are research studies that collect health information on exposure to medical products such as medicines (drugs) and vaccines during pregnancy. FDA does not run any pregnancy exposure registry studies. The registries on this page are posted based on a sponsor (company that makes the medical product) or another researcher’s request to list their registry. FDA does not endorse any registry and is not responsible for the content of registries listed on this webpage. This webpage may not represent a comprehensive list of pregnancy exposure registries. If you are a registry sponsor and would like your registry added to this list, please email FDA at Registries@fda.hhs.gov. This webpage is intended for informational purposes only.
| Medicine | Medical Condition | Registry | How to contact | Status | Sorting |
|---|---|---|---|---|---|
| Adbry (tralokinumab) | Atopic Dermatitis (AD) | Organization of Teratology Information Specialists (OTIS) Exposure Registry and Diseases in Pregnancy Study |
MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Phone: 1-877-311-8972 |
Ongoing | |
| Addyi® (flibanserin) |
Hypoactive Sexual Desire Disorder | Sprout Addyi Pregnancy Registry | https://addyipregnancy.com 1-855-265-6954 |
Ongoing | |
| Artesunate for Injection | Malaria | Observational Study of the Safety of Intravenous Artesunate Treatment of Pregnant Women and their Infants Registry |
Phone: Website: |
Ongoing | |
| Adderall (amphetamine) | ADD/ADHD | National Pregnancy Registry for Psychostimulants | Center for Women’s Mental Health at Massachusetts General Hospital Website: Phone: 1-866-961-2388 |
Ongoing |
|
| ERIVEDGE® (vismodegib) |
Adults with metastatic basal cell carcinoma, or with locally advanced basal cell carcinoma that has recurred following surgery or who are not candidates for surgery and who are not candidates for radiation. | Erivedge® (vismodegib) Pregnancy Pharmacovigilance Program | Website: https://www.erivedge.com/ Phone:1-888-835-2555 |
Ongoing | |
|
Evkeeza (evinacumab-dgnb) |
Homozygous Familial Hypercholesterolemia (HoFH) | Evkeeza (evinacumab-dgnb) Descriptive Pregnancy Study |
Phone: 1-844-734-6643 | Ongoing | |
| Nexletol; Nexlizet (bempedoic acid) |
High cholesterol [heterozygous familial hypercholesterolemia (HeFH) or established atherosclerotic cardiovascular disease (ASCVD)] | Bempedoic Acid Pregnancy Surveillance Program | Phone: +1 833 377 7633 (Option 5) | Ongoing | |
| Nurtec ODT (rimegepant) |
Migraine | A Prospective, Registry-based, Observational Study to Assess Maternal, Fetal and Infant Outcomes Following Exposure to Rimegepant: The Migraine Observational Nurtec Pregnancy Registry (MONITOR) |
Website: http://nurtecpregnancyregistry.com Phone: 1-877-366-0324 |
Ongoing | |
| Skyrizi (risankizumab-rzaa) | Psoriasis | The GLOW Pregnancy Registry: A prospective observational study on the safety of risankizumab exposure in pregnant women and their offspring |
Phone: 1-877-302-2161 Website: https://glowpregnancyregistry.com/ |
Ongoing | |
| Mayzent (siponimod) |
Multiple Sclerosis (MS) | Organization of Teratology Information Specialists (OTIS) Exposure Registry and Diseases in Pregnancy Study |
MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing-study/mayzent-siponimod/ Phone: 1-877-311-8972 |
Ongoing | |
| Comirnaty (Pfizer BioNTech COVID-19 vaccine) |
COVID-19 | Organization of Teratology Information Specialists (OTIS) Exposure Registry and Diseases in Pregnancy Study |
MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing-study/covid19-vaccines/ Phone: 1-877-311-8972 |
Ongoing | |
| Motegrity (prucalopride) |
Functional Constipation (Chronic idiopathic constipation (CID) or Irritable bowel disease – Constipation (IBS-C)) | Organization of Teratology Information Specialists (OTIS) Exposure Registry and Diseases in Pregnancy Study |
MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing-study/motegrity-prucalopride/ Phone: 1-877-311-8972 |
Ongoing | |
| Multiple Drugs | COVID-19 | COVID-19 International Drug Pregnancy Registry (COVID-PR) |
Website: https://covid-pr.pregistry.com Phone: 1-800-616-3791 |
Ongoing | |
| COVID-19 Vaccines (multiple products) | COVID-19 | COVID-19 Vaccine in Pregnancy and Lactation: Registry to Explore Immunization Practices, Outcomes and Quality Improvement Initiatives | URL: https://redcap.iths.org/surveys/?s=87JFRCL8R8 Email: covidvaccpreg@uw.edu |
Ongoing | |
| WAKIX (pitolisant) | Narcolepsy | WAKIX Pregnancy Registry – A prospective, observational cohort study designed to evaluate the association between pitolisant exposure during pregnancy and subsequent maternal, fetal, and infant outcomes | Website: https://wakixpregnancyregistry.com Phone: 1-877-302-2813 |
Ongoing | |
| Palforzia Peanut [Arachis hypogaea] Allergen Powder- dnfp |
Peanut Allergy | Palforzia Pregnancy Registry | Phone: 833-246-2566 (No webpage available) |
Ongoing | |
| Vyvanse (lisdexamfetamine dimesylate) | ADD/ADHD | National Pregnancy Registry for Psychostimulants | Center for Women’s Mental Health at Massachusetts General Hospital Website: Phone: 1-866-961-2388 |
Ongoing | |
| Mavenclad (cladribine tablets) | Multiple Sclerosis | Worldwide pregnancy surveillance program of oral cladribine - MAPLE-MS |
EMD Serono Research & Development Institute, Inc. an affiliate of Merck KGaA, Darmstadt, Germany |
Ongoing | |
|
Taltz (ixekizumab) |
Plaque Psoriasis, Psoriatic Arthritis, Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis | Taltz Pregnancy Registry | Phone: 1-800-284-1695 | Ongoing | |
|
MenQuadfi [meningococcal (Groups A, C, Y, W) conjugate vaccine] |
Vaccine - invasive meningococcal disease | MenQuadfi Vaccine Pregnancy Registry | Website: https://www.sanofipasteurpregnancyregistry.com/ Phone: 1-800-822-2463 |
Ongoing | |
| Ritalin (methylphenidate HCL) | ADD/ADHD | National Pregnancy Registry for Psychostimulants | Center for Women’s Mental Health at Massachusetts General Hospital Website: Phone: 1-866-961-2388 |
Ongoing | |
| Emgality (galcanezumab) | Migraine | Migraine Pregnancy Registry | Website: http://www.migrainepregnancyregistry.com Phone: 1-833-464-4724 |
Ongoing | |
| Aristada (aripiprazole lauroxil) | Mental Health Disorders | National Pregnancy Registry for Psychiatric Medications |
Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ or toll free at 1-866-961-2388 |
Ongoing | |
| Nuvigil (armodafinil) | Mental Health Disorders | National Pregnancy Registry for Psychiatric Medications | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ or toll free at 1-866-961-2388 | Ongoing | |
| Rexulti (brexpiprazole) | Mental Health Disorders | National Pregnancy Registry for Psychiatric Medications | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ or toll free at 1-866-961-2388 | Ongoing | |
| Spravato (esketamine) | Mental Health Disorders | National Pregnancy Registry for Psychiatric Medications | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ or toll free at 1-866-961-2388 | Ongoing | |
| Symbyax (olanzapine & fluoexetine) | Mental Health Disorders | National Pregnancy Registry for Psychiatric Medications | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ or toll free at 1-866-961-2388 | Ongoing | |
| Zulresso (brexanolone) | Mental Health Disorders | National Pregnancy Registry for Psychiatric Medications | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ or toll free at 1-866-961-2388 | Ongoing | |
COVID-19 Vaccines |
COVID-19 |
COVID-19 Vaccines International Pregnancy Exposure Registry (C-VIPER) | Phone: 1-800-616-3791 Website: https://c-viper.pregistry.com |
Ongoing | |
| Provigil (modafinil) |
Excessive sleepiness associated with: Obstructive Sleep Apnea Hypopnea Syndrome Narcolepsy Shift Work sleep disorder |
Provigil Pregnancy Registry | Website: http://provigilpregnancyregistry.com/ Phone: 1-866-404-4106 |
Ongoing opened | |
| Nuvigil (armodafinil) |
Excessive sleepiness associated with: Obstructive Sleep Apnea Hypopnea Syndrome Narcolepsy Shift Work sleep disorder |
Nuvigil Pregnancy Registry | Website: http://www.nuvigilpregnancyregistry.com/ Phone: Phone: 1-866-404-4106 (toll-free) |
Ongoing opened | |
| Metadate CD Methylin (methylphenidate HCL) |
ADD/ADHD | National Pregnancy Registry for Psychostimulants | Center for Women’s Mental Health at Massachusetts General Hospital Website: Phone: 1-866-961-2388 |
Ongoing | |
| Restoril (temazepam) |
Mental Health Disorders |
National Pregnancy Registry for Psychiatric Medications |
The MGH Center for Women’s Mental Health Phone: 1-866-961-2388 |
Ongoing | |
| Halcion (triazolam) |
Mental Health Disorders Insomnia |
National Pregnancy Registry for Psychiatric Medications |
The MGH Center for Women’s Mental Health Phone: 1-866-961-2388 |
Ongoing | |
| Doral (quazepam) |
Mental Health Disorders Insomnia |
National Pregnancy Registry for Psychiatric Medications |
The MGH Center for Women’s Mental Health Phone: 1-866-961-2388 |
Ongoing | |
| Ambien (zolpidem) |
Mental Health Disorders Insomnia |
National Pregnancy Registry for Psychiatric Medications |
The MGH Center for Women’s Mental Health Phone: 1-866-961-2388 |
Ongoing | |
| Lunesta (eszopiclone) |
Mental Health Disorders Insomnia |
National Pregnancy Registry for Psychiatric Medications |
The MGH Center for Women’s Mental Health Phone: 1-866-961-2388 |
Ongoing | |
| Galafold (migalastat) | Fabry Disease | A Global Prospective Observational Study of Women with Fabry Disease and Their Infants During Pregnancy and Breastfeeding |
Pregnancy Coordinating Center at United BioSource, LLC Website: www.fabrypregnancyregistry.com Phone: 1-855-239-0758 |
Ongoing | |
| Praluent (alirocumab) | High cholesterol (heterozygous familial hypercholesterolemia, atherosclerotic cardiovascular disease (ASCVD), homozygous familial hypercholesterolemia) | Praluent (alirocumab) Descriptive Pregnancy Study | Phone: 1-844-734-6643 [no webpage] |
Ongoing | |
| Dexedrine (dextroampehetamine) | ADD/ADHD | National Pregnancy Registry for Psychostimulants | Center for Women’s Mental Health at Massachusetts General Hospital Website: Phone: 1-866-961-2388 |
Ongoing | |
| Concerta Daytrana (methylphenidate) |
ADD/ADHD | National Pregnancy Registry for Psychostimulants | Center for Women’s Mental Health at Massachusetts General Hospital Website: Phone: 1-866-961-2388 |
Ongoing | |
| Aimovig (erenumab) | Preventive treatment of migraine in adults | AIMOVIG Pregnancy Exposure Registry |
Phone: 1-833-244-4083 |
Ongoing | |
| Dojolvi (triheptanoin) | Long-Chain Fatty Acid Oxidation Disorders | Long-Chain Fatty Acid Oxidation Disorders In-Clinic Disease Monitoring Program | Website: https://www.clinicaltrials.gov/ct2/show/NCT04632953 Phone: 1-415-483-8800 |
Ongoing | |
REYVOW (lasmiditan) |
Migraine | Migraine Pregnancy Registry | Website: http://www.migrainepregnancyregistry.com Phone: 1-833-464-4724 |
Ongoing | |
| Clozaril (clozapine) |
Mental Health Disorders | National Pregnancy Registry for Atypical Antipsychotics |
Center for Women’s Mental Health at Massachusetts General Hospital Phone: 1-866-961-2388 |
Ongoingopened | |
|
Fintepla |
Epilepsy | Antiepileptic Drug Pregnancy Registry | Massachusetts General Hospital Website: http://www.aedpregnancyregistry.org/ Phone: 1-888-233-2334 |
Ongoing | |
| Firdapse (amifampridine) | Lambert-Eaton Myasthenic Syndrome (LEMS) | Pregnancy Surveillance Program of Women and Infants Exposed to Firdapse During Pregnancy | Pregnancy Coordinating Center at United BioSource, LLC Website: http://www.firdapsepregnancystudy.com Phone: 1-855-212-5856 |
Ongoing | |
| Myfortic (mycophenolate) |
Immunosuppressive drug (renal transplant) | Mycophenolate Pregnancy Registry | Website: www.MycophenolateREMS.com Phone: 1-800-617-8191 Transplantation Pregnancy Registry International Phone: 1-877-955-6877 |
Ongoing opened | |
| Mycophenolate | Immunosuppressive drug (renal transplant) | Mycophenolate Pregnancy Registry |
Website: www.MycophenolateREMS.com Transplantation Pregnancy Registry International |
Ongoing opened | |
| Nucala (mepolizumab) | Asthma | The Mepolizumab Pregnancy Exposure Registry: OTIS Vaccines and Medications in Pregnancy Surveillance Study (VAMPSS) |
MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Phone: 1-877-311-8972 |
ongoing opened | |
| acitretin | Psoriasis | T.A.P.P. (Take Action to Prevent Pregnancy) | Pregnancy Monitoring Program for acitretin PPD, Inc. Website: http://www.tevagenerics.com/acitretin Phone: 1-855-850-2138 |
Ongoing opened | |
| Menactra (meningococca polysaccharide diptheria toxoid) |
Vaccine - Meningococcal Disease | Menactra vaccine Pregnancy Registry | Sanofi Pasteur Website: http://www.sanofipasteurpregnancyregistry.com/?fa=menactra Phone: 1-800-822-2463 |
Ongoing opened | |
| Provigil (modafinil) |
ADD/ADHD | National Pregnancy Registry for Psychostimulants | Center for Women’s Mental Health at Massachusetts General Hospital Website: Phone: 1-866-961-2388 |
Ongoing | |
| Multiple Drugs | Epilepsy | AED (Antiepileptic Drug) Pregnancy Registry | Massachusetts General Hospital Website: http://www.aedpregnancyregistry.org/ Phone: 1-888-233-2334 |
Ongoing | 1 |
| Multiple Drugs | Autoimmune Diseases: Crohn's Disease, Rheumatoid Arthritis, Psoriasis, Psoriatic Arthritis, Multiple Sclerosis (MS), Ulcerative Colitis | OTIS AutoImmune Diseases in Pregnancy Study |
MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Phone:1-877-311-8972 |
Ongoing | 1 |
| Multiple Drugs | Asthma | OTIS Vaccines and Medications in Pregnancy Surveillance Study |
MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Phone: 1-877-311-8972 |
Ongoing | 1 |
| Multiple Drugs | Cancer | Cancer and Childbirth Registry |
Cooper Health Phone: 1-877-635-4499 |
Ongoing | 1 |
| Multiple Drugs | HIV/AIDS | Antiretroviral Pregnancy Registry | Syneos Health Website: http://www.apregistry.com/ Phone: 1-800-258-4263 |
Ongoing | 1 |
| Multiple Drugs | Transplants Anti-rejection Medicines |
Transplantation Pregnancy Registry International |
Gift of Life Institute Phone: 1-877-955-6877 |
Ongoing | 1 |
| Abilify (aripiprazole) |
Mental Health Disorders | National Pregnancy Registry for Atypical Antipsychotics | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoing opened | |
| Actemra (tocilizumab) |
Any approved indication or indication currently in Phase III Trials | OTIS Autoimmune Diseases in Pregnancy Study | MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing-study/actemra/ Phone: 1-877-311-8972 |
Ongoing opened | |
| Ajovy (fremanezumab) | Preventive treatment of migraine in adults | Teva Migraine Pregnancy Registry | Phone: 833-927-2605 | Ongoing | |
| Anafranil (clomipramine) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoing opened | |
| Aldurazyme (laronidase) |
MPS I Mucopolysaccharidosis I Hurler's Syndrome Scheie's Syndrome Hurler-Scheie Syndrome |
MPSI Registry | Genzyme Corporation Website: www.registrynxt.com Phone: 800-633-1610 |
Ongoingopened | |
| Aptiom (eslicarbazepine) (acetate) |
antiepileptic drug | Antiepileptic Drug Pregnancy Registry | Massachusetts General Hospital Website: http://www.aedpregnancyregistry.org/ Phone: 1-888-233-2334 |
Ongoingopened | |
| Arava (leflunomide) |
Rheumatoid Arthritis | Leflunomide Pregnancy Registry OTIS Autoimmune Diseases in Pregnancy Study |
MotherToBaby: Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing- study/arava/ Phone: 1-877-311-8972 |
Ongoingopened | |
| Asendin (amoxapine) | Depression | National Pregnancy Registry for Antidepressants |
Center for Women’s Mental Health at Massachusetts General Hospital |
Ongoingopened | |
| Aubagio (teriflunomide) |
Multiple Sclerosis | OTIS Autoimmune Diseases in Pregnancy Study | MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing- study/aubagio/ Phone: 1-877-311-8972 |
Ongoingopened | |
| BENLYSTA (belimumab) |
Systemic Lupus Erythematosus (SLE) | Organization of Teratology Information Specialists (OTIS) Exposure Registry and Diseases in Pregnancy Study |
MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing-study/benlysta-belimumab/ Phone: 1-877-311-8972 |
Ongoing | |
| Bexsero (Meningococcal Group B Vaccine) | Meningitis Vaccine | Bexsero Pregnancy Registry |
PPD, Inc. Phone: 1-877-413-4759 |
Ongoingopened | |
| BREXAFEMME® (ibrexafungerp tablets) |
Vulvovaginal candidiasis or vaginal yeast infection |
BREXAFEMME® Pregnancy Safety Study |
Phone: 1 888 982 7299 |
Ongoing | |
| Brintellix (vortioxetine) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Bylvay (odevixibat) |
Progressive familial intrahepatic cholestasis (PFIC) | Odevixibat Pregnancy and Lactation Surveillance Program, Protocol A4250-017 | Phone: 1-877-390-2762 | Ongoing | |
| CAMZYOS (mavacamten) |
Obstructive hypertrophic cardiomyopathy | Mavacamten Pregnancy Surveillance Program | Phone: 1-877-390-2852 | Ongoing | |
| Celexa (citalopram) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Cellcept (mycophenolate) |
Immunosuppressive drug (renal transplant) | Mycophenolate Pregnancy Registry |
Website: www.MycophenolateREMS.com Phone: 1-800-617-8191 Transplantation Pregnancy Registry International |
Ongoingopened | |
|
Certican® (everolimus) |
Any transplant recipient | Transplant Pregnancy Registry International |
Phone: 215-599-2078 and |
Ongoing | |
| Cimzia (certolizumab pegol) |
Rheumatoid Arthritis Psoriatic Arthritis Ankylosing Spondylitis, Crohn's Disease |
OTIS Autoimmune Diseases in Pregnancy Study | MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing- study/cimzia/ Phone: 1-877-311-8972 |
Ongoingopened | |
|
CIBINQO |
Atopic Dermatitis | CIBINQO Pregnancy Registry |
Phone: 1-877-311-3770 |
Ongoing | |
| Dengvaxia [CYD tetravalent dengue vaccine (live attenuated)] |
Vaccine - prevention of dengue disease caused by dengue virus serotypes 1, 2, 3 and 4 | Dengvaxia US Pregnancy Registry |
Webpage: https://www.sanofipasteurpregnancyregistry.com/product/Dengvaxia/ Phone: 1-800-822-2463 |
Ongoing | |
| Desyrel (trazodone) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoing | |
| Desoxyn (Methamphetamine HCl) | ADD/ADHD | National Pregnancy Registry for Psychostimulants | Center for Women’s Mental Health at Massachusetts General Hospital Website: Phone: 1-866-961-2388 |
Ongoing | |
| Direct-Acting Antivirals (Multiple Drugs) | Hepatitis C Virus | Treatment in Pregnancy for Hepatitis C Registry ("TiP-HepC" Registry) |
Coalition for Global Hepatitis Elimination Website: https://www.globalhep.org/evidence-base/treatment-pregnancy-hepatitis-c-tip-hepc-registry |
Ongoing | |
| Dupixent (dupilumab) | Atopic Dermatitis, Asthma | Organization of Teratology Information Specialists (OTIS) Exposure Registry and Diseases in Pregnancy Study | MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing-study/dupixent/ Phone: 1-877-311-8972 |
Ongoing | |
| Effexor (venlafaxine) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoing opened | |
| Effexor XR (Venlafaxine Hydrochloride) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoing opened | |
| Elavil (amitriptyline) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoing opened | |
| Entyvio (vedolizumab) | Crohn's Disease and Ulcerative Colitis | OTIS Autoimmune Diseases in Pregnancy Study | MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing- study/entyvio/ Phone: 1-877-311-8972 |
Ongoing | |
| ENSPRYNG ® (satralizumab - mwge) |
Neuromyelitis optica spectrum disorder | ENSPRYNG (satralizumab) Pregnancy Registry | Website: www.enspryngpregnancyregistry.com Phone: 1-833-277-9338 |
Ongoing | |
| Emsam(selegiline) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoing opened | |
|
Envarsus XR® (tacrolimus extended-release tablets) |
Any transplant recipient | Transplant Pregnancy Registry International |
Phone: 215-599-2078 and |
Ongoing | |
| Epidiolex (cannabidiol) | Epilepsy | Antiepileptic Drug Pregnancy Registry | Massachusetts General Hospital Website: http://www.aedpregnancyregistry.org/ Phone: 1-888-233-2334 |
Ongoing | |
| EPIDIOLEX EPIDYOLEX (cannabidiol) |
Epidiolex is used for the treatment of seizures associated with LGS (Lennox-Gastaut syndrome), DS (Dravet syndrome), or TSC (Tuberous sclerosis complex) in patients 1 year of age and older | Epidiolex Pregnancy Surveillance Program | Website: www.epidiolexpregnancystudy.com Phone Number: 1-855-272-7158 |
Ongoing | |
| Fabrazyme (agalsidase beta) |
Fabry Disease | Fabry Registry | Genzyme Corporation Website: www.registrynxt.com Phone: 800-633-1610 |
Ongoingopened | |
| Fanapt (iloperidone) |
Mental Health Disorders | National Pregnancy Registry for Atypical Antipsychotics |
Center for Women’s Mental Health at Massachusetts General Hospital Phone: 1-866-961-2388 |
Ongoingopened | |
| Fasenra (benralizumab) | Asthma | The Benralizumab Pregnancy Exposure Study: OTIS Vaccines and Medications in Pregnancy Surveillance Study (VAMPSS) | MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing-study/fasenra/ Phone: 1-877-311-8972 |
Ongoing | |
| Fetzima (levomilnacipran) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Fluoxetine (Fluoxetine Hydrochloride) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Focalin (Dextroampehetamine) | ADD/ADHD | National Pregnancy Registry for Psychostimulants | Center for Women’s Mental Health at Massachusetts General Hospital Website: Phone: 1-866-961-2388 |
Ongoing | |
| Forfivo (Bupropion Hydrochloride) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Geodon (ziprasidone) |
Mental Health Disorders | National Pregnancy Registry for Atypical Antipsychotics |
Center for Women’s Mental Health at Massachusetts General Hospital Phone: 1-866-961-2388 |
Ongoingopened | |
| Gilenya (fingolimod) |
Multiple Sclerosis (MS) | The Gilenya Pregnancy Registry | Phone Novartis Pharmaceuticals: 1-877-598-7237
Website: http://www.gilenyapregnancyregistry.com Email: gpr@quintiles.com or gpr@IQVIA.com |
Ongoingopened | |
| HEPLISAV-B (Recombinant, Adjuvanted) |
Hepatitis B | HEPLISAV-B [Hepatitis B Vaccine (Recombinant), Adjuvanted] Pregnancy Registry | Dynavax Technology Corporation/PPD Phone 1-844-443-7734 |
Ongoing | |
| Ilumya (tildrakizumab) | Psoriasis | Organization of Teratology Information Specialists (OTIS) Autoimmune Diseases in Pregnancy Study | MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing-study/ilumya/ Phone: 1-877-311-8972 |
Ongoing | |
|
Imuran® (azathioprine) |
Any transplant recipient | Transplant Pregnancy Registry International |
Phone: 215-599-2078 and |
Ongoing | |
| Invega (paliperidone) |
Mental Health Disorders | National Pregnancy Registry for Atypical Antipsychotics |
Center for Women’s Mental Health at Massachusetts General Hospital Phone: 1-866-961-2388 |
Ongoingopened | |
| Juxtapid (lomitapide) |
Homozygous Familial Hypercholesterolemia | Global Lomitapide Pregnancy Exposure Registry | Aegerion Website: www.JUXTAPID.com Phone: 1-877-902-4099 |
Ongoingopened | |
| Kesimpta (ofatumumab) | Multiple Sclerosis (MS) | Organization of Teratology Information Specialists (OTIS) Exposure Registry and Diseases in Pregnancy Study |
MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Phone: 1-877-311-8972 |
Ongoing | |
| Kevzara (sarilumab) | Rheumatoid Arthritis | Organization of Teratology Information Specialists (OTIS) Autoimmune Diseases in Pregnancy Study | MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing-study/kevzara/ Phone: 1-877-311-8972 |
Ongoing | |
| Latuda (lurasidone) |
Mental Health Disorders | National Pregnancy Registry for Atypical Antipsychotics |
Center for Women’s Mental Health at Massachusetts General Hospital Phone: 1-866-961-2388 |
Ongoingopened | |
| LAMPIT (nifurtimox) |
Chagas' disease (American Trypanosomiasis) |
Lampit Pregnancy Exposure Registry in the US and LATAM | Phone: 1-877-899-1393 | Ongoing | |
| Lemtrada (alemtuzumab) |
Multiple Sclerosis | Lemtrada Pregnancy Surveillance Program | Phone: 1-800-745-4447 (No webpage) |
Ongoing | |
| LEQVIO (inclisiran) |
Primary hypercholesterolemia | Monitoring of pregnancy outcomes in women treated with inclisiran: a non-interventional study | Phone: 1-888-669-6682 | Ongoing | |
| Lexapro (escitalopram) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Ludiomil (maprotiline) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Luvox (fluvoxamine) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Lyrica (pregabalin) |
antiepileptic, neuropathic pain | Antiepileptic Drug Pregnancy Registry | Massachusetts General Hospital Website: http://www.aedpregnancyregistry.org/ Phone: 1-888-233-2334 |
Ongoingopened | |
| Marplan (Isocarboxazid) | Depression | National Pregnancy Registry for Antidepressants | Center for Women's Health Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-844-405-6185 |
Ongoingopened | |
| Myfembree (relugolix combination therapy) |
Uterine fibroids and/or endometriosis | MyRose Pregnancy Registry: Myfembree Relugolix Observational Study of Pregnancies |
Website: www.relugolixCTpregnancyregistry.com |
Ongoing | |
| Myozyme (alglucosidase alfa) |
Pompe Disease (GAA deficiency) |
Pompe Disease Registry | Genzyme Corporation Website: www.registrynxt.com Phone: 800-633-1610 |
Ongoingopened | |
| Naglazyme | Maroteaux-Lamy Syndrome also known as Polydystrophic Dwarfism or Mucopolysaccharidosis VI | MPS VI Clinical Surveillance Program (CSP) | Website: https://clinicaltrials.gov/ct/show/NCT00214773?order=2 | Ongoingopened | |
| Nardil (phenelzine) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
|
Neoral® (cyclosporine modified, USP) |
Any transplant recipient | Transplant Pregnancy Registry International |
Phone: 215-599-2078 and |
Ongoing | |
| Norpramin (desipramine) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Nulojix (belatacept) |
Immunosuppressive drug (renal transplant) | Transplantation Pregnancy Registry International | Gift of Life Institute Website: http://www.transplantpregnancyregistry.org/ Phone: 1-877-955-6877 |
Ongoingopened | |
| Ocrevus (ocrelizumab) | Multiple Sclerosis | Ocrevus Pregnancy Registry | https://www.ocrevuspregnancyregistry.com/ Phone: 1-833-872-4370 |
Ongoing | |
| Onpattro (patisiran) | hATTR Amyloidosis | Onpattro Pregnancy Exposure Registry | Alnylampregnancyprogram@iqvia.com Phone: 1-877-256-9526 |
Ongoing | |
| OPZELURA® (ruxolitinib) cream | Atopic Dermatitis (eczema) |
OPZELURA (ruxolitinib) Cream Pregnancy Registry | Website: www.opzelura.pregnancy.incyte.com Phone: 1-833-917-8791 Email: OpzeluraCreamPregnancyRegistry@syneoshealth.com |
Ongoing | |
| Oriahnn (elagolix/estradiol/norethindrone acetate and elagolix) |
Heavy menstrual bleeding associated with uterine leiomyomas (fibroids) in premenopausal women | Prospective Registry to Evaluate Pregnancy Outcomes in Women Treated with Elagolix | Website: https://www.bloompregnancyregistry.com/ Phone: 833-782-7241 |
Ongoing | |
| Orilissa (elagolix) |
Moderate to Severe Pain Associated with Endometriosis | Prospective Registry to Evaluate Pregnancy Outcomes in Women Treated with Elagolix | Website: https://www.bloompregnancyregistry.com/ Phone: 833-782-7241 |
Ongoing | |
| Otezla (apremilast) |
Psoriatic Arthritis Psoriasis |
OTIS AutoImmune Diseases in Pregnancy Study | MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing- study/otezla/ Phone: Phone: 1-877-311-8972 (toll-free) |
Ongoingopened | |
| Pamelor (nortriptyline) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Parnate (tranylcypromine) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Paxil (paroxetine) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Pristiq (desvenlafaxine) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
|
Prograf®, Advagraf®, Astagraf® (tacrolimus) |
Any transplant recipient | Transplant Pregnancy Registry International |
Phone: 215-599-2078 and |
Ongoing | |
| Prolia (denosumab) |
osteoporosis | Amgen's Pregnancy Surveillance Program | Website: http://www.amgenpregnancy.com/en-us/patient/home.aspx Phone: 1-800-772-6436 |
Ongoingopened | |
| Promacta (eltrombopag) |
Thrombocytopenia (ITP) | Promacta Pregnancy Registry GlaxoSmithKline Pregnancy Registry |
Global Clinical Safety and Pharmacovigilance Phone: 888-825-5249 |
Ongoingopened | |
| Prozac (fluoxetine) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
|
Rapamune® (sirolimus) |
Any transplant recipient | Transplant Pregnancy Registry International |
Phone: 215-599-2078 and |
Ongoing | |
| Remeron (mirtazapine) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Repatha (evolocumab) | High cholesterol (heterozygous familial hypercholesterolemia, atherosclerotic cardiovascular disease (ASCVD), homozygous familial hypercholesterolemia) | An Observational Case Series to Describe Women Exposed to Repatha During Pregnancy Infant Outcomes During the First Year of Life |
Phone:1-800-772-6436 (toll-free) |
Ongoing | |
| Risperdal (risperidone) |
Mental Health Disorders | National Pregnancy Registry for Atypical Antipsychotics |
Center for Women’s Mental Health at Massachusetts General Hospital Phone: 1-866-961-2388 |
Ongoingopened | |
| Saphris (asenapine) |
Mental Health Disorders | National Pregnancy Registry for Atypical Antipsychotics |
Center for Women’s Mental Health at Massachusetts General Hospital Phone: 1-866-961-2388 |
Ongoingopened | |
|
Sandimmune® (cyclosporine) |
Any transplant recipient | Transplant Pregnancy Registry International |
Phone: 215-599-2078 and |
Ongoing | |
| Savella | Fibromyalgia | Savella Pregnancy Registry | Website: www.savellapregnancyregistry.com Phone: 877-643-3010 |
Ongoingopened | |
| Seroquel (quetiapine) |
Mental Health Disorders | National Pregnancy Registry for Atypical Antipsychotics | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Serzone (nefazodone) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Sinequan (doxepin) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Stelara (ustekinumab) |
Psoriatic Arthritis Psoriasis |
OTIS Autoimmune Diseases in PregnancyStudy | MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing- study/stelara/ Phone: 1-877-311-8972 |
Ongoingopened | |
| Surmontil (trimipramine) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Tecfidera (dimethyl fumarate) | Multiple Sclerosis | TecGistry | RWE Solutions Website: https://www.tecfiderapregnancyregistry.com/ Phone: 1-866-810-1462 |
Ongoing | |
| Tofranil (imipramine) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Tremfya (guselkumab) | Psoriasis | Organization of Teratology Information Specialists (OTIS) Autoimmune Diseases in Pregnancy Study | MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Website: https://mothertobaby.org/ongoing-study/tremfya/ Phone: 1-877-311-8972 |
Ongoing | |
| Tegsedi (inotersen) |
Polyneuropathy of Hereditary Transthyretin-mediated Amyloidosis (hATTR-PN) | Pregnancy Surveillance Program of Women and Infants Exposed to TEGSEDI During Pregnancy | Pregnancy Coordinating Center at United BioSource, LLC Website: www.tegsedipregnancystudy.com Phone: 1-877-465-7510 |
Ongoing | |
| Ubrelvy (ubrogepant) |
Migraine | The EMPRESS Pregnancy Registry | Website: https://www.empresspregnancyregistry.com/ Phone: 1-833-782-7241 |
Ongoing | |
| UPLIZNA (inebilizumab-cdon) |
Neuromyelitis Optica Spectrum Disorder (NMOSD) | UPLIZNA Pregnancy Safety Study | Website: https://www.UPLIZNApregnancyregistry.com Phone: 1-303-724-4644 |
Ongoing | |
| Ultomiris® (Ravulizumab) | Paroxysmal Nocturnal Hemoglobinuria (PNH) Atypical Hemolytic Uremic Syndrome (aHUS) Generalized Myasthenia Gravis (gMG) Neuromyelitis Optica Spectrum Disorder (NMOSD) |
Study of Ultomiris® (Ravulizumab) Safety in Pregnancy |
Website: https://www.ultomirispregnancystudy.com Phone Number: +1-833-793-0563 |
Ongoing | |
| VERQUVO® (vericiguat) |
Heart Failure | A Pregnancy Surveillance Program (PSUP) to Collect and Analyze Information on Pregnancy Outcomes in Women with Symptomatic Chronic Heart Failure with Ejection Fraction less than 45% and Worsening Heart Failure Event who were Exposed to Vericiguat During Pregnancy |
Phone: 1-877-888-4231 Webpages: (English): https://pregnancyreporting.verquvo-us.com |
Ongoing | |
| Vyndaqel (tafamidis meglumine) |
Transthyretin amyloid cardiomyopathy | Tafamidis Enhanced Surveillance for Pregnancy Outcomes (TESPO) | Pfizer Phone: 1-800-438-1985 |
Ongoing | |
| Vyndamax (tafamidis) |
Transthyretin amyloid cardiomyopathy | Tafamidis Enhanced Surveillance for Pregnancy Outcomes (TESPO) | Pfizer Phone: 1-800-438-1985 |
Ongoing | |
| Vibativ (telavancin) |
Antibacterial for skin infection | Vibativ Pregnancy Registry | Website: www.clinicaltrials.gov Phone: 1-855-633-8479 |
Ongoingopened | |
| Viibryd (Vilazodone Hydrochloride) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Vivactil (protriptyline) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
|
VUMERITY® (diroximel fumarate) |
Multiple Sclerosis | BlossoMS Pregnancy Registry | Phone: 1-833-569-2635 website: www.vumeritypregnancyregistry.com |
Ongoing | |
| Vyepti (eptinezumab) |
Migraine | The VYEPTI Pregnancy Registry |
Website: https://vyeptipregnancyregistry.lundbeck/ Phone: 1-855-810-8549 |
Ongoing | |
| Vyvgart (efgartigimod alfa-fcab) and Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase-qvfc) | Generalized Myasthenia Gravis | National Pregnancy Registry for Vyvgart (efgartigimod alfa-fcab) and Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase-qvfc) | Phone: 1-855-272-6524 Website: www.vyvgartpregnancy.com |
Ongoing | |
| Wegovy (semaglutide) |
Obesity | Wegovy Pregnancy Registry | Website: https://wegovypregnancyregistry.com Phone: 1-877-390-2760 |
Ongoing | |
| Wellbutrin (buproprion) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Wellbutrin SR (buproprion Hydrochloride) | Depression | National Pregnancy Registry for Antidepressants | Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Xeljanz (tofacitinib) |
Rheumatoid Arthritis | OTIS Autoimmune Diseases in Pregnancy Study |
MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists (OTIS) Phone: 1-877-311-8972 |
Ongoingopened | |
| ZEPOSIA® (ozanimod) |
Multiple sclerosis (MS) | Zeposia MS Pregnancy Registry: A Study on the Safety of Ozanimod Exposure in Pregnant Women and Their Offspring |
Webpage: Phone: 877-301-9314 |
Ongoing | |
| Zoloft (sertraline) | Depression | National Pregnancy Registry for Antidepressants |
Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened | |
| Zyprexa (olanzapine) |
Mental Health Disorders | National Pregnancy Registry for Atypical Antipsychotics |
Center for Women’s Mental Health at Massachusetts General Hospital Website: https://womensmentalhealth.org/research/pregnancyregistry/ Phone: 1-866-961-2388 |
Ongoingopened |