Fosfomycin Injection

	Minimum Inhibitory  Concentrations (mcg/mL)			Disk Diffusionb  (zone diameters in mm)
Pathogen	S	I	R	S	I	R
Escherichia colia	≤ 8	16	≥ 32	≥ 24	21-23	≤ 20
Klebsiella pneumoniaea	≤ 32	64	≥ 128	≥ 18	15-17	≤ 14

S = Susceptible; I = Intermediate; R = Resistant

^a. Susceptibility interpretive criteria are based on a dose of 6 grams fosfomycin every 8 hours by intravenous infusion over 1 hour in patients with an estimated creatinine clearance of 50 mL/min.

^b. For disk diffusion, use paper disks impregnated with 200 mcg fosfomycin supplemented with 50 mcg of glucose-6-phosphate.