Preventing and Mitigating Drug Interactions
Patients frequently use more than one drug at a time. One type of drug-drug interaction (DDI) can occur when a co-administered drug alters the drug concentrations (pharmacokinetics) of another drug.
These changes could result in reduced efficacy or increased side effects for the affected drug(s). Thus, evaluating the risk of a DDI is a critical aspect of the benefit-risk assessment of new drugs prior to market approval and during the postmarketing period.
The assessment of DDIs also informs drug labeling that is often used by healthcare providers to aid in therapeutic decision-making. This Website provides resources relevant to DDIs. Visit the pages below to learn more.