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  1. Development & Approval Process | Drugs

Ciprofloxacin Oral, Injection products

Recognized Interpretive Criteria

Additional FDA-identified interpretive criteria

 

Minimum Inhibitory
Concentrations

(mcg/mL)

Disk Diffusion
(zone diameter in mm)

Pathogen

S

I

R

S

I

R

Enterobacteriaceae

M100 standard is recognized

Pseudomonas aeruginosa

M100 standard is recognized

Staphylococcus spp.

M100 standard is recognized

Enterococcus spp.

M100 standard is recognized

Haemophilus influenzae and
parainfluenzae

M100 standard is recognized

Neisseria gonorrhoeae

M100 standard is recognized

Streptococcus pneumoniae

≤1

 2

≥4

≥21

 16-20

≤15

Streptococcus spp. β-
Hemolytic Group

≤1

 2

≥4

≥21

 16-20

≤15

Bacillus anthracis

M45 standard is recognized

-

-

-

Yersinia pestis

M45 standard is recognized

-

-

-

S = Susceptible; I = Intermediate; R = Resistant

Exceptions to the recognized standard of CLSI M100

For these bacteria listed below, susceptibility test interpretive criteria are not recognized at this time:

Acinetobacter spp.

Other Non-Enterobacteriaceae

Neisseria meningitides