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  1. Liver Toxicity Knowledge Base (LTKB)

Drug-Induced Liver Injury Severity and Toxicity (DILIst) Dataset

The largest drug list with DILI classification

The drug-induced liver injury severity and toxicity (DILIst) dataset is an updated version of the DILIrank dataset. DILIst consists of 1,279 drugs that are divided into two classes according to their potential for causing drug-induced liver injury (DILI). The DILI classification was derived from augmenting the DILIrank dataset with four literature datasets that were found to have ≥ 350 drugs with human DILI classification, to generate the largest drug list with DILI classification.

  • 768 DILI Positive
  • 511 DILI Negative

Please let us know if you download the file by contacting NCTRBioinformaticsSupport@fda.hhs.gov.

Reference:

Shraddha Thakkar, Ting Li, Zhichao Liu, Leihong Wu, Ruth Roberts, and Weida Tong. Drug-induced liver injury severity and toxicity (DILIst): binary classification of 1279 drugs by human hepatotoxicity. Drug Discovery Today. 2020, 25(1), 201-208. https://doi.org/10.1016/j.drudis.2019.09.022

Contact Information:

Questions or Suggestions: Shraddha Thakkar, Ph.D. (Shraddha.Thakkar@fda.hhs.gov) or Weida Tong, Ph.D. (Weida.Tong@fda.hhs.gov)


*Classification: 0 = DILI Negative; 1 = DILI Positive

DILIST_ID Compound Name DILIst Classification Routes of Administration
1 mercaptopurine 1 Oral
2 acetaminophen 1 Oral
3 azathioprine 1 Oral
4 chlorpheniramine 0 Oral
5 clofibrate 1 Oral
6 cyclophosphamide 1 Oral
7 dopamine 0 Intravenous
8 estradiol 1 Oral
9 fluoxetine 1 Oral
10 gemfibrozil 1 Oral
11 indomethacin 1 Oral
12 ketoprofen 1 Oral
13 mannitol 0 Intravenous
14 methotrexate 1 Oral
15 phenobarbital 1 Oral
16 phenytoin 1 Oral
17 rifampin 1 Oral
18 tetracycline 1 Oral
19 abacavir 1 Oral
20 aciclovir 1 Oral
21 allopurinol 1 Oral
22 amineptine 1 Oral
23 amiodarone 1 Oral
24 amitriptyline 1 Oral
25 amphotericin b 1 Intravenous
26 ampicillin 1 Oral
27 donepezil 1 Oral
28 aspirin 1 Oral
29 aminohippurate 0 Intravenous
30 bicalutamide 1 Oral
31 bupropion 1 Oral
32 captopril 1 Oral
33 carbamazepine 1 Oral
34 carboplatin 1 Intravenous
35 ceftazidime 1 Intravenous
36 chlorcyclizine 1 Oral
37 chlorzoxazone 1 Oral
38 chlorpromazine 1 Oral
39 cisplatin 1 Intravenous
40 dimercaprol 0 Intramuscular
41 colchicine 0 Oral
42 corticotropin 0 Subcutaneous
43 dactinomycin 1 Subcutaneous
44 dantrolene 1 Oral
45 demeclocycline 0 Oral
46 propoxyphene 1 Oral
47 diclofenac 1 Oral
48 diflunisal 1 Oral
49 diphenhydramine 0 Oral
50 epirubicin 0 Intravenous
51 erythromycin 1 Oral
52 etoposide 1 Oral
53 famotidine 1 Oral
54 felbamate 1 Oral
55 fenofibrate 1 Oral
56 fenoprofen 1 Oral
57 flutamide 1 Oral
58 hydroxyurea 1 Oral
59 imatinib 1 Oral
60 imipramine 1 Oral
61 iproniazid 1 Oral
62 ketoconazole 1 Oral
63 labetalol 1 Oral
64 leflunomide 1 Oral
65 mefenamic acid 1 Oral
66 meloxicam 1 Oral
67 metformin 1 Oral
68 methyldopa 1 Oral
69 nefazodone 1 Oral
70 nitrofurantoin 1 Oral
71 olsalazine 1 Oral
72 paroxetine 1 Oral
73 pentamidine 1 Intravenous
74 perhexiline 1 Oral
75 physostigmine 0 Intravenous
76 pioglitazone 1 Oral
77 propylthiouracil 1 Oral
78 pseudoephedrine 0 Oral
79 ranitidine 1 Oral
80 rifabutin 1 Oral
81 rosiglitazone 1 Oral
82 indocyanine green 0 Intravenous
83 simvastatin 1 Oral
84 spironolactone 1 Oral
85 stavudine 1 Oral
86 streptomycin 0 Intramuscular
87 sulfadiazine 1 Oral
88 sulfasalazine 1 Oral
89 sulindac 1 Oral
90 tamoxifen 1 Oral
91 temozolomide 1 Oral
92 theophylline 0 Oral
93 tizanidine 1 Oral
94 tolcapone 1 Oral
95 valproic acid 1 Oral
96 vancomycin 1 Oral
97 vitamin a 1 Intramuscular
98 zidovudine 1 Oral
99 zolpidem 0 Oral
100 zonisamide 1 Oral
101 pyrazinamide 1 Oral
102 finasteride 1 Oral
103 troglitazone 1 Oral
104 fluvastatin 1 Oral
105 glimepiride 1 Oral
106 venlafaxine 1 Oral
107 amlodipine 1 Oral
108 vinblastine 0 Intravenous
109 ciprofloxacin 1 Oral
110 fluconazole 1 Oral
111 prednisone 1 Oral
112 lorazepam 0 Oral
113 itraconazole 1 Oral
114 raloxifene 0 Oral
115 mifepristone 0 Oral
116 clomipramine 1 Oral
117 pravastatin 1 Oral
118 clarithromycin 1 Oral
119 hydrocortisone 0 Oral
120 progesterone 1 Oral
121 ergocalciferol 0 Oral
122 ibuprofen 1 Oral
123 isoproterenol 0 Intravenous
124 ketorolac 1 Oral
125 promethazine 1 Oral
126 omeprazole 1 Oral
127 carvedilol 1 Oral
128 cytarabine 1 Intravenous
129 pergolide 0 Oral
130 nisoldipine 0 Oral
131 citalopram 1 Oral
132 methyltestosterone 1 Oral
133 testosterone 1 Oral
134 praziquantel 0 Oral
135 ticlopidine 1 Oral
136 diazepam 0 Oral
137 clomiphene 1 Oral
138 isotretinoin 1 Oral
139 oxymetholone 1 Oral
140 etodolac 1 Oral
141 glipizide 1 Oral
142 pemoline 1 Oral
143 clotrimazole 1 Oral
144 celecoxib 1 Oral
145 amoxapine 0 Oral
146 iothalamate sodium 0 Intravenous
147 atorvastatin 1 Oral
148 olanzapine 1 Oral
149 nevirapine 1 Oral
150 primidone 0 Oral
151 vinorelbine 0 Intravenous
152 anastrozole 1 Oral
153 rabeprazole 1 Oral
154 azithromycin 1 Oral
155 tolazamide 1 Oral
156 quetiapine 1 Oral
157 famciclovir 0 Oral
158 atenolol 1 Oral
159 benzbromarone 1 Oral
160 bromocriptine 1 Oral
161 busulfan 1 Oral
162 chlorambucil 1 Oral
163 clozapine 1 Oral
164 dacarbazine 1 Intravenous
165 dapsone 1 Oral
166 digoxin 0 Oral
167 disulfiram 1 Oral
168 enalapril 1 Oral
169 furosemide 0 Oral
170 gabapentin 1 Oral
171 glibenclamide 1 Oral
172 isoniazid 1 Oral
173 lansoprazole 1 Oral
174 mebendazole 1 Oral
175 metoprolol 1 Oral
176 naltrexone 0 Oral
177 niacin 1 Oral
178 nifedipine 1 Oral
179 nimesulide 1 Oral
180 nizatidine 1 Oral
181 dextrose 0 Intravenous
182 cholestyramine 0 Oral
183 sodium lactate 0 Intravenous
184 verapamil 1 Oral
185 doxorubicin 1 Intravenous
186 clorazepate 0 Oral
187 protirelin 0 Intravenous
188 sincalide 0 Intravenous
189 secretin 0 Intravenous
190 sucralfate 0 Oral
191 cupric chloride 0 Intravenous
192 trientine hydrochloride 0 Oral
193 chlorpropamide 1 Oral
194 cyclosporine 1 Oral
195 decitabine 0 Intravenous
196 deferoxamine 1 Intravenous
197 doxycycline 1 Oral
198 exemestane 1 Oral
199 felodipine 1 Oral
200 fludrocortisone 0 Oral
201 fluphenazine 0 Oral
202 gefitinib 1 Oral
203 haloperidol 1 Oral
204 mesalazine 1 Oral
205 minocycline 1 Oral
206 ioversol 0 Intravenous
207 oxaprozin 1 Oral
208 paclitaxel 1 Intravenous
209 phentolamine 0 Intravenous
210 prazosin 0 Oral
211 prochlorperazine 1 Oral
212 corticorelin ovine triflutate 0 Intravenous
213 sodium thiosulfate 0 Intravenous
214 sirolimus 1 Oral
215 tacrolimus 1 Oral
216 thalidomide 1 Oral
217 thioridazine 1 Oral
218 thioguanine 1 Oral
219 tolbutamide 0 Oral
220 topiramate 1 Oral
221 trifluoperazine 0 Oral
222 triptorelin pamoate 1 Intramuscular
223 alatrofloxacin mesylate 1 Oral
224 vorinostat 0 Oral
225 nesiritide 0 Intravenous
226 ganirelix acetate 0 Subcutaneous
227 gemtuzumab ozogamicin 1 Intravenous
228 methylprednisolone 1 Oral
229 gamma hydroxybutyric acid 0 Oral
230 tegaserod 0 Oral
231 penicillamine 1 Oral
232 pramlintide 0 Subcutaneous
233 lanthanum carbonate 0 Oral
234 acetazolamide 1 Oral
235 albendazole 1 Oral
236 alprazolam 1 Oral
237 altretamine 0 Oral
238 amantadine 0 Oral
239 4-aminosalicylic acid 1 Oral
240 amoxicillin 1 Oral
241 atropine 0 Intravenous
242 benoxaprofen 1 Oral
243 emtricitabine 0 Oral
244 trospium 0 Oral
245 bromfenac 1 Oral
246 gadofosveset trisodium 0 Intravenous
247 clonazepam 1 Oral
248 exenatide 0 Subcutaneous
249 entecavir 0 Oral
250 danazol 1 Oral
251 daunorubicin 0 Intravenous
252 dimenhydrinate 0 Intravenous
253 doxapram 0 Intravenous
254 febuxostat 1 Oral
255 granisetron 0 Oral
256 griseofulvin 1 Oral
257 hydralazine 1 Oral
258 ibufenac 1 Oral
259 ifosfamide 1 Intravenous
260 deferasirox 1 Oral
261 sunitinib 1 Oral
262 ivermectin 1 Oral
263 lamivudine 1 Oral
264 methylnaltrexone bromide 0 Subcutaneous
265 letrozole 1 Oral
266 desvenlafaxine 1 Oral
267 lomefloxacin 0 Oral
268 lomustine 1 Oral
269 lovastatin 1 Oral
270 telbivudine 0 Oral
271 methimazole 1 Oral
272 methocarbamol 0 Oral
273 metronidazole 1 Oral
274 minoxidil 0 Oral
275 mitomycin 1 Intravenous
276 modafinil 1 Oral
277 fesoterodine 0 Oral
278 naloxone 0 Intravenous
279 naproxen 1 Oral
280 nateglinide 0 Oral
281 neomycin 0 Oral
282 levocetirizine dihydrochloride 1 Oral
283 nystatin 0 Oral
284 oxytetracycline 0 Oral
285 pantoprazole 1 Oral
286 prednisolone 1 Oral
287 primaquine 0 Oral
288 procarbazine 1 Oral
289 ambrisentan 0 Oral
290 secobarbital 0 Oral
291 sertraline 1 Oral
292 sotalol 0 Oral
293 sulfathiazole 1 Oral
294 terbinafine 1 Oral
295 thiabendazole 1 Oral
296 ticrynafen 1 Oral
297 tinidazole 1 Oral
298 maraviroc 1 Oral
299 raltegravir 1 Oral
300 clevidipine 0 Intravenous
301 trovafloxacin 1 Oral
302 regadenoson 0 Intravenous
303 warfarin 1 Oral
304 zaleplon 0 Oral
305 zileuton 1 Oral
306 ferumoxytol 0 Intravenous
307 etravirine 1 Oral
308 silodosin 0 Oral
309 fospropofol 1 Intravenous
310 bendamustine 0 Intravenous
311 tolvaptan 1 Oral
312 eltrombopag olamine 1 Oral
313 tapentadol 0 Oral
314 prasugrel hydrochloride 1 Oral
315 saxagliptin 0 Oral
316 romidepsin 0 Intravenous
317 dronedarone 1 Oral
318 pazopanib 1 Oral
319 pancrelipase 0 Oral
320 dexchlorpheniramine 0 Oral
321 ecallantide 0 Subcutaneous
322 divalproex sodium 1 Oral
323 lumiracoxib 1 Oral
324 tasosartan 1 Oral
325 oxyphenisatin 1 Oral
326 tilbroquinol 1 Oral
327 alclofenac 1 Oral
328 aplaviroc  1 Oral
329 clomacran 1 Oral
330 dermatan 1 Intravenous
331 isaxonine 1 Oral
332 pipamazine 1 Oral
333 pralnacasan  1 Oral
334 sulfacarbamide 1 Oral
335 triacetyldiphenolisatin 1 Oral
336 fiduxosin  1 Oral
337 pafuramidine  1 Oral
338 phenoxypropazine 1 Oral
339 histamine diphosphate 0 Subcutaneous
340 aminophylline 0 Oral
341 meperidine 0 Oral
342 methamphetamine 0 Oral
343 methadone 0 Oral
344 hyaluronidase 0 Subcutaneous
345 doxylamine 0 Oral
346 protamine sulfate 0 Intravenous
347 bethanechol 0 Oral
348 cortisone acetate 0 Oral
349 dicyclomine 0 Oral
350 norepinephrine 0 Intravenous
351 dyphylline 0 Oral
352 epinephrine 0 Subcutaneous
353 succinylcholine 0 Intravenous
354 thyrotropin alfa 0 Intramuscular
355 levorphanol 0 Oral
356 propantheline 0 Oral
357 carbinoxamine 0 Oral
358 diatrizoate 0 Intravenous
359 phytonadione 0 Oral
360 mecamylamine 0 Oral
361 liothyronine 0 Oral
362 methsuximide 0 Oral
363 mepenzolate 0 Oral
364 meclizine 0 Oral
365 triprolidine 0 Oral
366 benzonatate 1 Oral
367 Sodium polystyrene sulfonate 0 Oral
368 dichlorphenamide 0 Oral
369 phentermine 1 Oral
370 diethylpropion 0 Oral
371 oxymorphone 0 Oral
372 dexbrompheniramine 0 Oral
373 biperiden 0 Oral
374 isosorbide dinitrate 0 Oral
375 mepivacaine 0 Subcutaneous
376 bendroflumethiazide 1 Oral
377 phendimetrazine 0 Oral
378 oxytocin 0 Intravenous
379 guanethidine 0 Oral
380 ethosuximide 0 Oral
381 benzphetamine 0 Oral
382 glycopyrrolate 0 Oral
383 metyrapone 0 Oral
384 metaxalone 1 Oral
385 oxandrolone 1 Oral
386 oxazepam 0 Oral
387 protriptyline 0 Oral
388 cosyntropin 0 Intravenous
389 flavoxate 0 Oral
390 ketamine 1 Intravenous
391 pancuronium 0 Intravenous
392 pentagastrin 0 Intravenous
393 dextroamphetamine 0 Oral
394 terbutaline 1 Oral
395 calcitonin salmon 0 Subcutaneous
396 pentetic acid 0 Intravenous
397 nitroprusside 0 Intravenous
398 colestipol 0 Oral
399 lactulose 0 Oral
400 somatropin recombinant 0 Subcutaneous
401 fluorescein 0 Intravenous
402 metyrosine 0 Oral
403 carboprost tromethamine 0 Intramuscular
404 calcitriol 0 Oral
405 morphine 0 Oral
406 nabilone 0 Oral
407 vecuronium 0 Intravenous
408 atracurium 0 Intravenous
409 hydromorphone 0 Oral
410 sufentanil 0 Intravenous
411 tranexamic acid 0 Oral
412 alfentanil 0 Intravenous
413 ethanolamine oleate 0 Intravenous
414 rubidium chloride rb-82 0 Intravenous
415 urofollitropin 0 Subcutaneous
416 teriparatide 0 Subcutaneous
417 gadopentetate dimeglumine 0 Intravenous
418 rimantadine 0 Oral
419 pegademase bovine 0 Intramuscular
420 fenoldopam 0 Intravenous
421 calcium acetate 0 Oral
422 mivacurium 0 Intravenous
423 gadoteridol 0 Intravenous
424 enoxaparin 1 Subcutaneous
425 perindopril 0 Oral
426 rocuronium 0 Intravenous
427 dalteparin sodium 1 Subcutaneous
428 ferumoxsil 0 Oral
429 ferumoxides 0 Intravenous
430 porfimer 0 Intravenous
431 ibutilide 0 Intravenous
432 cisatracurium besylate 0 Intravenous
433 oxycodone 0 Oral
434 alendronate 1 Oral
435 tamsulosin 1 Oral
436 dolasetron 0 Oral
437 remifentanil 1 Intravenous
438 sibutramine 1 Oral
439 tiagabine 0 Oral
440 ropinirole 1 Oral
441 pramipexole 0 Oral
442 miglitol 0 Oral
443 polyethylene glycol 3350 0 Oral
444 delavirdine 0 Oral
445 tiludronate 0 Oral
446 eptifibatide 0 Intravenous
447 eprosartan 0 Oral
448 repaglinide 1 Oral
449 irbesartan 1 Oral
450 naratriptan 0 Oral
451 zolmitriptan 0 Oral
452 tolterodine 0 Oral
453 nelfinavir 1 Oral
454 rivastigmine 1 Oral
455 ziprasidone 1 Oral
456 risedronate 0 Oral
457 candesartan 1 Oral
458 clopidogrel 1 Oral
459 rizatriptan 0 Oral
460 bivalirudin 0 Intravenous
461 azacitidine 0 Intravenous
462 fluorouracil 1 Intravenous
463 argatroban 0 Intravenous
464 sildenafil 1 Oral
465 acarbose 1 Oral
466 acebutolol 1 Oral
467 tirofiban 0 Intravenous
468 sevelamer 0 Oral
469 dofetilide 0 Oral
470 acetylcysteine 0 Oral
471 acitretin 1 Oral
472 gadoversetamide 0 Intravenous
473 adenosine 0 Intravenous
474 salbutamol 0 Oral
475 almotriptan 0 Oral
476 frovatriptan 0 Oral
477 oxcarbazepine 1 Oral
478 rifapentine 0 Oral
479 levetiracetam 1 Oral
480 alpidem 1 Oral
481 bexarotene 1 Oral
482 perflutren 0 Intravenous
483 amifostine 0 Intravenous
484 amikacin 0 Intravenous
485 alosetron 1 Oral
486 aminocaproic acid 0 Oral
487 levothyroxine 1 Oral
488 linezolid 1 Intravenous
489 colesevelam 0 Oral
490 gemifloxacin 1 Oral
491 desloratadine 1 Oral
492 galantamine 0 Oral
493 cefditoren 0 Oral
494 zoledronate 1 Intravenous
495 caspofungin 0 Intravenous
496 atovaquone 0 Oral
497 voriconazole 1 Oral
498 guaifenesin 0 Oral
499 olmesartan 0 Oral
500 alfuzosin 1 Oral
501 aztreonam 0 Intravenous
502 dutasteride 0 Oral
503 baclofen 1 Oral
504 benazepril 1 Oral
505 bendazac 1 Oral
506 benzarone 1 Oral
507 benziodarone 1 Oral
508 ertapenem 0 Intravenous
509 benztropine 0 Oral
510 fondaparinux sodium 1 Subcutaneous
511 miglustat 0 Oral
512 gadobenate dimeglumine 0 Intravenous
513 rifaximin 0 Oral
514 tadalafil 0 Oral
515 palonosetron 0 Intravenous
516 betaxolol 0 Oral
517 vardenafil 0 Oral
518 bisoprolol 0 Oral
519 bleomycin 0 Intravenous
520 atomoxetine 1 Oral
521 bosentan 1 Oral
522 acamprosate 1 Oral
523 aripiprazole 0 Oral
524 budesonide 0 Oral
525 bumetanide 0 Oral
526 buspirone 0 Oral
527 eplerenone 0 Oral
528 butorphanol 0 Intravenous
529 cabergoline 0 Oral
530 ezetimibe 1 Oral
531 pregabalin 1 Oral
532 adefovir 1 Oral
533 ibandronate 0 Oral
534 carbenicillin 1 Oral
535 carbidopa 0 Oral
536 eszopiclone 0 Oral
537 cefaclor 1 Oral
538 cefadroxil 1 Oral
539 enfuvirtide 0 Subcutaneous
540 cefazolin 1 Intravenous
541 cefepime 1 Intravenous
542 cefixime 0 Oral
543 cefoperazone 1 Intravenous
544 cefotaxime 1 Intravenous
545 cefoxitin 0 Intravenous
546 cefpodoxime 0 Oral
547 oxaliplatin 1 Intravenous
548 cefprozil 1 Oral
549 ceftibuten 0 Oral
550 nitazoxanide 0 Oral
551 ceftriaxone 1 Intravenous
552 cefuroxime 1 Oral
553 micafungin 1 Intravenous
554 darifenacin 0 Oral
555 cephalexin 1 Oral
556 cetirizine 1 Oral
557 solifenacin 0 Oral
558 ranolazine 0 Oral
559 chloramphenicol 0 Intravenous
560 chlordiazepoxide 1 Oral
561 atazanavir 1 Oral
562 daptomycin 1 Intravenous
563 chlormezanone 1 Oral
564 bortezomib 1 Intravenous
565 anidulafungin 0 Intravenous
566 rasagiline 0 Oral
567 chloroquine 1 Oral
568 chlorothiazide 1 Oral
569 cinacalcet 0 Oral
570 conivaptan 0 Intravenous
571 nebivolol 0 Oral
572 chlorthalidone 0 Oral
573 erlotinib 1 Oral
574 alvimopan 0 Oral
575 cidofovir 0 Intravenous
576 ramelteon 0 Oral
577 cimetidine 1 Oral
578 cinchophen 1 Oral
579 tipranavir 1 Oral
580 tigecycline 0 Intravenous
581 cladribine 0 Intravenous
582 clindamycin 1 Oral
583 clometacin 1 Oral
584 urokinase 0 Intravenous
585 clonidine 0 Oral
586 nelarabine 1 Intravenous
587 cloxacillin 1 Oral
588 lenalidomide 1 Oral
589 lubiprostone 0 Oral
590 sorafenib 1 Oral
591 varenicline 1 Oral
592 darunavir 1 Oral
593 aliskiren 1 Oral
594 dasatinib 1 Oral
595 cyclobenzaprine 1 Oral
596 cyclofenil 1 Oral
597 sitagliptin 1 Oral
598 paliperidone 0 Oral
599 posaconazole 0 Oral
600 cyproheptadine 1 Oral
601 temsirolimus 0 Intravenous
602 tetrahydrobiopterin 0 Oral
603 milnacipran 1 Oral
604 desipramine 0 Oral
605 dexlansoprazole 1 Oral
606 everolimus 0 Oral
607 codeine 0 Oral
608 colistimethate 0 Intravenous
609 benzylpenicilloyl polylysine 0 Subcutaneous
610 cephradine 0 Oral
611 ceftizoxime 0 Intravenous
612 didanosine 1 Oral
613 mycophenolate mofetil 1 Oral
614 cefdinir 1 Oral
615 polymyxin b sulfate 0 Intravenous
616 diltiazem 1 Oral
617 sterile water 0 Intravenous
618 disopyramide 1 Oral
619 asparaginase 1 Intravenous
620 botulinum toxin type a 0 Intramuscular
621 interferon alfa-2b 1 Intravenous
622 dobutamine 0 Intravenous
623 docetaxel 1 Intravenous
624 interferon alfa-2a, recombinant 1 Subcutaneous
625 doxazosin 0 Oral
626 doxepin 1 Oral
627 alteplase 0 Intravenous
628 epoetin alfa 0 Intravenous
629 droperidol 0 Intravenous
630 droxicam 1 Oral
631 sargramostim 0 Intravenous
632 pegaspargase 1 Intravenous
633 efavirenz 1 Oral
634 muromonab-cd3 0 Intravenous
635 interferon beta-1b 1 Subcutaneous
636 abciximab 0 Intravenous
637 interferon beta-1a 1 Intramuscular
638 esmolol 0 Intravenous
639 estazolam 0 Oral
640 interferon alfacon-1 1 Subcutaneous
641 oprelvekin 0 Subcutaneous
642 estramustine 1 Oral
643 ethambutol 1 Oral
644 basiliximab 0 Intravenous
645 ethionamide 1 Oral
646 palivizumab 0 Intramuscular
647 infliximab 1 Intravenous
648 reteplase 0 Intravenous
649 trastuzumab 1 Intravenous
650 etanercept 1 Subcutaneous
651 etidronic acid 0 Oral
652 botulinum toxin type b 0 Intramuscular
653 etomidate 0 Intravenous
654 exifone 1 Oral
655 tenecteplase 0 Intravenous
656 rasburicase 0 Intravenous
657 alemtuzumab 0 Intravenous
658 peginterferon alfa-2b 1 Subcutaneous
659 fexofenadine 0 Oral
660 fialuridine 1 Oral
661 fipexide 1 Oral
662 anakinra 1 Subcutaneous
663 darbepoetin alfa 1 Intravenous
664 flecainide 1 Oral
665 omalizumab 0 Subcutaneous
666 ibritumomab tiuxetan 0 Intravenous
667 pegfilgrastim 0 Subcutaneous
668 flucytosine 0 Oral
669 fludarabine 0 Oral
670 flumazenil 0 Intravenous
671 adalimumab 1 Subcutaneous
672 cetuximab 0 Intravenous
673 bevacizumab 0 Intravenous
674 palifermin 0 Intravenous
675 natalizumab 1 Intravenous
676 flurazepam 1 Oral
677 fluvoxamine 0 Oral
678 foscarnet 0 Intravenous
679 fosfomycin 1 Oral
680 fosinopril 1 Oral
681 fosphenytoin 1 Intramuscular
682 galsulfase 0 Intravenous
683 abatacept 1 Intravenous
684 alglucosidase alfa 0 Intravenous
685 gemcitabine 1 Intravenous
686 panitumumab 0 Intravenous
687 idursulfase 0 Intravenous
688 certolizumab pegol 0 Subcutaneous
689 eculizumab 0 Intravenous
690 rilonacept 0 Subcutaneous
691 ustekinumab 0 Subcutaneous
692 romiplostim 0 Subcutaneous
693 ofatumumab 0 Intravenous
694 hydrochlorothiazide 1 Oral
695 idarubicin 0 Intravenous
696 indapamide 0 Oral
697 indinavir 0 Oral
698 iodipamide meglumine 0 Intravenous
699 irinotecan 1 Intravenous
700 l-methionine 0 Oral
701 isradipine 1 Oral
702 kanamycin 0 Intravenous
703 riboflavin 0 Oral
704 lamotrigine 1 Oral
705 l-carnitine 0 Oral
706 levofloxacin 1 Oral
707 levonorgestrel 0 Oral
708 lisinopril 1 Oral
709 loracarbef 1 Oral
710 loratadine 0 Oral
711 losartan 1 Oral
712 loxapine 0 Oral
713 mebanazine 1 Oral
714 mechlorethamine 0 Intravenous
715 mefloquine 1 Oral
716 vitamin e 0 Oral
717 melphalan 1 Oral
718 meprobamate 0 Oral
719 meropenem 1 Intravenous
720 methazolamide 1 Oral
721 methoxsalen 1 Oral
722 methylphenidate 1 Oral
723 methylscopolamine bromide 0 Oral
724 metoclopramide 1 Oral
725 mexiletine 1 Oral
726 midazolam 0 Oral
727 midodrine 0 Oral
728 mirtazapine 1 Oral
729 mitotane 0 Oral
730 mitoxantrone 1 Intravenous
731 moexipril 0 Oral
732 moxisylyte 1 Oral
733 folic acid 0 Oral
734 nabumetone 0 Oral
735 nadolol 0 Oral
736 nafcillin 1 Intravenous
737 nalbuphine 0 Intravenous
738 nialamide 1 Oral
739 nicardipine 0 Oral
740 nimodipine 0 Oral
741 niperotidine 1 Oral
742 nitroglycerin 0 Oral
743 nomifensine 1 Oral
744 norfloxacin 1 Oral
745 nortriptyline 1 Oral
746 octreotide 1 Intravenous
747 ondansetron 1 Oral
748 ofloxacin 1 Oral
749 diphenoxylate 0 Oral
750 oxacillin 1 Intravenous
751 ambenonium 0 Oral
752 papaverine 1 Intravenous
753 penbutolol 0 Oral
754 penicillin g 1 Intravenous
755 penicillin v 0 Oral
756 pentazocine 0 Intravenous
757 pentostatin 1 Intravenous
758 perphenazine 1 Oral
759 phenelzine 1 Oral
760 ephedrine 0 Intravenous
761 pimozide 0 Oral
762 pindolol 0 Oral
763 piperacillin 0 Intravenous
764 piroxicam 1 Oral
765 pirprofen 1 Oral
766 salsalate 1 Oral
767 polythiazide 0 Oral
768 probenecid 0 Oral
769 procainamide 1 Intravenous
770 propafenone 1 Oral
771 propranolol 0 Oral
772 propofol 1 Intravenous
773 pyrantel 0 Oral
774 pyrimethamine 1 Oral
775 quazepam 0 Oral
776 quinapril 1 Oral
777 quinidine 1 Oral
778 ramipril 1 Oral
779 reserpine 0 Oral
780 ribavirin 0 Oral
781 riluzole 1 Oral
782 risperidone 1 Oral
783 ritonavir 1 Oral
784 saquinavir 1 Oral
785 selegiline 0 Oral
786 succimer 1 Oral
787 sumatriptan 0 Oral
788 temazepam 0 Oral
789 teniposide 1 Intravenous
790 terazosin 0 Oral
791 thiotepa 1 Intravenous
792 timolol 0 Oral
793 sulcotidil 1 Oral
794 tolmetin 1 Oral
795 tolrestat 1 Oral
796 topotecan 0 Oral
797 tramadol 0 Oral
798 trandolapril 1 Oral
799 tranylcypromine 1 Oral
800 trazodone 1 Oral
801 triamterene 1 Oral
802 triazolam 0 Oral
803 trihexyphenidyl 0 Oral
804 trimethobenzamide 0 Oral
805 trimethoprim 1 Oral
806 fenclozic acid 1 Oral
807 ebrotidine 1 Oral
808 aceclofenac 1 Oral
809 nitrefazole 1 Oral
810 valaciclovir 1 Oral
811 valsartan 1 Oral
812 tetrabamate 1 Oral
813 vincristine 1 Intravenous
814 xenazoic acid 1 Oral
815 zafirlukast 1 Oral
816 falnidamol  1 Oral
817 zimelidine 1 Oral
818 caffeine 0 Intravenous
819 capreomycin 0 Intravenous
820 lidocaine 0 Oral
821 memantine 1 Oral
822 pamidronate 0 Intravenous
823 quinine 1 Oral
824 rosuvastatin 1 Oral
825 sulfamethizole 1 Oral
826 telithromycin 1 Oral
827 entacapone 1 Oral
828 valdecoxib 1 Oral
829 dexpanthenol 0 Intravenous
830 scopolamine 0 Intravenous
831 pyridoxine 0 Intravenous
832 thiamine 0 Intravenous
833 cyanocobalamin 0 Subcutaneous
834 cromoglicate 1 Oral
835 montelukast 1 Oral
836 moxifloxacin 1 Oral
837 vitamin c 0 Intravenous
838 sorbitol 0 Oral
839 capecitabine 0 Oral
840 leuprolide 1 Subcutaneous
841 eletriptan 0 Oral
842 hydroxychloroquine 1 Oral
843 ximelagatran 1 Oral
844 duloxetine 1 Oral
845 carisoprodol 0 Oral
846 dicloxacillin 1 Oral
847 metolazone 0 Oral
848 pamabrom 0 Oral
849 dextromethorphan 0 Oral
850 bacitracin 0 Intramuscular
851 paromomycin 0 Oral
852 telmisartan 1 Oral
853 ammonium chloride 0 Intravenous
854 amiloride 1 Oral
855 methysergide 0 Oral
856 methylergonovine 0 Oral
857 brompheniramine 0 Oral
858 l-arginine 0 Intravenous
859 pyridostigmine 0 Oral
860 phenoxybenzamine 0 Oral
861 oxybutynin 0 Oral
862 orphenadrine 0 Oral
863 loperamide 0 Oral
864 isoxsuprine 0 Oral
865 glafenine 1 Oral
866 acetylcholine chloride 0 Oral
867 amphetamine 1 Oral
868 mepazine 1 Oral
869 nandrolone decanoate 1 Intramuscular
870 auranofin 1 Oral
871 simethicone 0 Oral
872 betaine 0 Oral
873 bisacodyl 0 Oral
874 leucovorin 0 Oral
875 lapatinib 1 Oral
876 oseltamivir 0 Oral
877 alaproclate 1 Oral
878 orlistat 1 Oral
879 apomorphine 0 Subcutaneous
880 dihydroergotamine 0 Intravenous
881 procyclidine 0 Oral
882 clemastine 0 Oral
883 tenofovir 1 Oral
884 norethindrone acetate 0 Oral
885 exametazime 0 Intravenous
886 erythropoietin 0 Intravenous
887 Argipressin 0 Intravenous
888 sodium bicarbonate 0 Intravenous
889 plerixafor 0 Subcutaneous
890 tyramine 0 Oral
891 Hetastarch 0 Intravenous
892 imiglucerase 0 Intravenous
893 agalsidase beta 0 Intravenous
894 gadolinium ethoxybenzyl DTPA 0 Intravenous
895 canakinumab 1 Subcutaneous
896 Levoleucovorin 0 Intravenous
897 levomefolate calcium 0 Oral
898 sitaxsentan 1 Oral
899 dexmethylphenidate 1 Oral
900 hyaluronidase recombinant human 0 Subcutaneous
901 Androgenic steroids* 1  
902 Floxuridine 1 Intra-arterial
903 Flucloxacillin 1 oral
904 Halothane 1 Respiratory (inhalation)
905 Peginterferon 1  
906 Sulfonamides* 1 oral
907 Acetohexamide 1 oral
908 Dabigatran 1 oral
909 Gliclazide 1 Oral
910 Imipenem 1 Intravenous
911 Lopinavir 1 Oral
912 Molindone 1 Oral
913 Plicamycin 1  
914 Rilpivirine 1 Oral
915 Tibolone 1  
916 Tobramycin 1  
917 Vismodegib 1 Oral
918 Hydrocodone 0 Oral
919 Zalcitabine 0 Oral
920 Acrivastine 0 Oral
921 Amobarbital 0 Intramuscular; Intravenous, oral
922 Artemether 0 Oral
923 Bitolterol 0  
924 Butalbital 0 Oral
925 Butobarbital 0  
926 Carmustine 0 Intravenous
927 Chloral hydrate 0 Oral
928 Chlortetracycline 0 Tropical
929 Cilastatin 0 Intravenous
930 Cisapride 0 Oral
931 Cobicistat 0 Oral
932 Docusate 0 oral
933 Ergotamine 0 oral
934 Ethacrynate 0 oral
935 Fentanyl 0 Sublingual
936 Formoterol 0 Respiratory (inhalation)
937 Gentamicin 0 Intramuscular; Intravenous
938 Homatropine 0 Ophthalmic
939 Hyoscyamine 0 oral
940 Ipratropium 0 Oral; Respiratory (inhalation)
941 Levamisole 0 Oral
942 Levodopa 0 Oral
943 Liraglutide 0 Subcutaneous
944 Nalmefene 0 Oral
945 Pegaptanib 0 Intravitreal
946 Proguanil 0 Oral
947 Salmeterol 0 Oral; Respiratory (inhalation)
948 Tazobactam 0 Intravenous; Parenteral
949 Thiopental 0 Intravenous
950 Ticarcillin 0 Intramuscular; Intravenous
951 Tiotropium 0 Oral; Respiratory (inhalation)
952 Zanamivir 0 Oral; Respiratory (inhalation)
953 ACEMETACIN 1  
954 ACETARSOL 1 Vaginal
955 Alatrofloxacin 1  
956 Alimemazine 1 Oral
957 ANDROSTANOLONE 1  
958 Antithymocyte Immunoglobulin 1  
959 Artemisinin 1  
960 Artesunate 1  
961 bendazolic acid 1  
962 Bupivacaine 1 Epidural; Infiltration; Intracaudal; Perineural
963 CALCIUM CARBIMIDE 1 Oral
964 CARBIMAZOLE 1  
965 Cerivastatin 1 Oral
966 CILAZAPRIL 1 Oral
967 CINITAPRIDE 1  
968 Clomacron 1  
969 CLOMETHIAZOLE 1  
970 CLOTIAZEPAM 1  
971 COCAINE 1 Nasal, Torpical
972 CYPROTERONE 1 Oral, Intramuscular
973 Dehydroepiandrosterone 1  
974 Desflurane 1 Respiratory (inhalation)
975 DEXKETOPROFEN 1  
976 Diacetoxydiphenolisatin 1  
977 DICOUMAROL 1  
978 EBASTINE 1  
979 ENFLURANE 1 Respiratory (inhalation)
980 ESTRIOL 1  
981 Ethinylestradiol 1 Oral, Transdermal
982 ETRETINATE 1  
983 FLUPENTIXOL 1 Oral, Intramuscular
984 Fusidic Acid 1 Oral, Topical, Intravenous, optahlmic
985 Gemtuzumab 1  
986 GLUCOSAMINE 1 Topical
987 Growth Hormone 1 Intravenous
988 Interferon Unspecified 1  
989 Interferon-Beta-1a 1  
990 interferon-Beta-1b 1  
991 Ioxaglate And Meglumine 1 Intravascular
992 Isaxonine phosphate 1 Oral,Intramuscular; Intravenous
993 JOSAMYCIN 1  
994 LEVOMEPROMAZINE 1 Oral,Intramuscular; Intravenous
995 Melperone 1  
996 METAMIZOLE 1  
997 Methoxyflurane 1  
998 Methylene Dioxymethamphetamine 1  
999 NIFLUMIC ACID 1  
1000 Oxyiminoalkanoic acid derivative 1  
1001 Peginterferon-Alfa-2a 1  
1002 PENICILLIN 1  
1003 Phenisatin 1  
1004 Pivmecillinam 1 Oral
1005 RITODRINE 1 Oral, Intravenous
1006 ROFECOXIB 1 Oral
1007 ROXITHROMYCIN 1  
1008 STANOZOLOL 1  
1009 STREPTOKINASE 1 Intracoronary; Intravenous
1010 Suloctidil 1  
1011 TACRINE 1  
1012 TENOXICAM 1 Oral
1013 TIRATRICOL 1  
1014 TRIPTORELIN 1 Subcutaneous, Intramuscular
1015 phenacetin 1  
1016 bithionol 1  
1017 hexachlorophene 1 Topical
1018 methapyrilene 1  
1019 tripelennamine 1 Topical, Oral, vaginal
1020 oxyquinoline 1 oral, Topical,Vaginal, Dental
1021 meticillin 1  
1022 amsacrine 1 Intravenous
1023 furazolidone 1  
1024 hycanthone 1  
1025 idoxuridine 1 Opthalmic, Topical
1026 novobiocin 1  
1027 tianeptine 1  
1028 methacycline 1  
1029 bepridil 1  
1030 betahistine 1 Oral
1031 ciprofibrate 1  
1032 diethylcarbamazine 1 Oral
1033 fenoterol 1 Oral; Respiratory (inhalation)
1034 phenylbutazone 1 Oral
1035 ethynodiol diacetate 1 Oral
1036 atractyloside 1  
1037 temafloxacin 1  
1038 cefamandole 1 Intramuscular; Intravenous
1039 amodiaquine 1  
1040 glutethimide 1  
1041 sulfanilamide 1 Vaginal
1042 2-acetylaminofluorene 1  
1043 demecarium bromide 1  
1044 cefalotin 1 Intramuscular; Intravenous
1045 uracil mustard 1  
1046 methylphenobarbital 1  
1047 acenocoumarol 1 Oral
1048 1-naphthylisothiocyanate 1  
1049 aflatoxin b1 1  
1050 indacrinone 1  
1051 cefotiam 1  
1052 troleandomycin 1  
1053 perhexiline maleate 1  
1054 ciglitazone 1  
1055 fluspirilene 1 Intramuscular
1056 norgestrel 1 Oral
1057 carbon tetrachloride 1  
1058 aurothioglucose 1 Intramuscular
1059 phenothiazine 1  
1060 allyl alcohol 1  
1061 bromobenzene 1  
1062 azatadine 1 Oral
1063 allyl formate 1  
1064 tauroursodeoxycholic acid 1  
1065 octylmethoxycinnamate 1  
1066 ketotifen 0 Opthalmic, Topical
1067 permethrin 0 Topical
1068 oxyphenonium 0  
1069 pyridoxal phosphate 0 Oral
1070 aminoglutethimide 0 Oral
1071 tetracaine 0 Topical
1072 miconazole 0 Topical
1073 lindane 0 Topical
1074 astemizole 0 Oral
1075 ciclopirox 0 Topical
1076 pinacidil 0  
1077 terfenadine 0 Oral
1078 methoxamine 0 Intramuscular; Intravenous
1079 beclomethasone 0 Topical,Respiratory (inhalation)
1080 vidarabine 0  
1081 bezafibrate 0 oral
1082 bambuterol 0  
1083 gallamine triethiodide 0 Intravenous
1084 melatonin 0 Oral
1085 nocodazole 0  
1086 zomepirac 0  
1087 alloxan 0  
1088 pargyline 0  
1089 probucol 0 Oral
1090 lactose 0 Oral
1091 anileridine 0 Oral, Intramuscular; Intravenous; Subcutaneous
1092 citicoline 0  
1093 mometasone 0 Topical,Respiratory (inhalation)
1094 capsaicin 0 Percutaneous; Topical; Transdermal
1095 ergonovine 0 Oral, Intramuscular; Intravenous
1096 econazole 0 Topical
1097 sulconazole nitrate 0 Topical
1098 sulfabenzamide 0  
1099 cephapirin 0  
1100 azlocillin 0  
1101 butoconazole 0 Vaginal
1102 mibefradil 0  
1103 ragaglitazar 0  
1104 bismuth subsalicylate 0 Oral
1105 isoxicam 0  
1106 inositol 0 Oral, Vaginal
1107 latamoxef 0  
1108 Abiraterone 1  
1109 Acetorphan 1  
1110 Alfacalcidol 1  
1111 Ambroxol 1  
1112 Aminolevulinic acid 1  
1113 Amisulpride 1  
1114 Ampiroxicam 1  
1115 Anethole 1  
1116 Arbekacin 1  
1117 Axitinib 1  
1118 Azelnidipine 1  
1119 Bacampicillin 1  
1120 Benidipine 1  
1121 Beraprost 1  
1122 Boceprevir 1  
1123 Bromazepam 1  
1124 Bromhexine 1  
1125 Bromisoval 1  
1126 Brotizolam 1  
1127 Bucillamine 1  
1128 Buflomedil 1  
1129 Buprenorphine 1  
1130 Cabazitaxel 1  
1131 Cefcapene 1  
1132 Cefmetazole 1  
1133 Cefozopran 1  
1134 Cefpirome 1  
1135 Celiprolol 1  
1136 Chlormadinone 1  
1137 Cibenzoline 1  
1138 Cilnidipine 1  
1139 Clobazam 1  
1140 Clobetasol 1  
1141 Clodronic acid 1  
1142 Clofazimine 1  
1143 Cloperastine 1  
1144 Crizotinib 1  
1145 Curcumin 1  
1146 Cyamemazine 1  
1147 Cyclothiazide 1  
1148 Desogestrel 1  
1149 Diacerein 1  
1150 Dihydrocodeine 1  
1151 Dirithromycin 1  
1152 Domperidone 1  
1153 Doxifluridine 1  
1154 Droxidopa 1  
1155 Dydrogesterone 1  
1156 Edaravone 1  
1157 Eltrombopag 1  
1158 Eperisone 1  
1159 Epinastine 1  
1160 Eribulin Mesylate 1  
1161 Ethanol 1  
1162 Ethyl loflazepate 1  
1163 Ethylene glycol 1  
1164 Etizolam 1  
1165 Etoricoxib 1  
1166 Flomoxef 1  
1167 Fluindione 1  
1168 Flunitrazepam 1  
1169 Flupirtine 1  
1170 Fominoben 1  
1171 Fosfluconazole 1  
1172 Fudosteine 1  
1173 Gabapentin Enacarbil 1  
1174 Gabexate 1  
1175 Garenoxacin 1  
1176 Glutathione 1  
1177 Glycerol 1  
1178 Glycyrrhizin 1  
1179 Halofantrine 1  
1180 Heptaminol 1  
1181 Hypericin 1  
1182 Ibudilast 1  
1183 Iloprost 1  
1184 Irsogladine 1  
1185 Isepamicin 1  
1186 Isosorbide 1  
1187 Itopride 1  
1188 Lafutidine 1  
1189 Lanreotide 1  
1190 Lercanidipine 1  
1191 Levocetirizine 1  
1192 Lodenosine 1  
1193 Lormetazepam 1  
1194 Lornoxicam 1  
1195 Loxoprofen 1  
1196 Manidipine 1  
1197 Mazindol 1  
1198 Menatetrenone 1  
1199 Mequitazine 1  
1200 Metopimazine 1  
1201 Mitiglinide 1  
1202 Mizoribine 1  
1203 Molsidomine 1  
1204 Mosapride 1  
1205 Moxonidine 1  
1206 Nafamostat 1  
1207 Naftidrofuryl 1  
1208 Nandrolone 1  
1209 Nefopam 1  
1210 Netilmicin 1  
1211 Nicergoline 1  
1212 Nicorandil 1  
1213 Nitrazepam 1  
1214 Nitrendipine 1  
1215 Nordazepam 1  
1216 Norethisterone 1  
1217 Olopatadine 1  
1218 Oxatomide 1  
1219 Oxyphenbutazone 1  
1220 Ozagrel 1  
1221 Pazufloxacin 1  
1222 Peramivir 1  
1223 Phenformin 1  
1224 Phenprocoumon 1  
1225 Phenylephrine 1  
1226 Phloroglucinol 1  
1227 Picolamine 1  
1228 Pilsicainide 1  
1229 Pimecrolimus 1  
1230 Pinaverium 1  
1231 Piperacetazine 1  
1232 Pipobroman 1  
1233 Piracetam 1  
1234 Pirarubicin 1  
1235 Pranlukast 1  
1236 Pranoprofen 1  
1237 Prazepam 1  
1238 Propacetamol 1  
1239 Propiverine 1  
1240 Raltitrexed 1  
1241 Rebamipide 1  
1242 Rilmenidine 1  
1243 Rivaroxaban 1  
1244 Roxatidine 1  
1245 Salicylic acid 1  
1246 Sarpogrelate 1  
1247 Sennoside 1  
1248 Sofalcone 1  
1249 Sparfloxacin 1  
1250 Sulfamethoxazole 1  
1251 Sulpiride 1  
1252 Suplatast 1  
1253 Tandospirone 1  
1254 Telaprevir 1  
1255 Temocapril 1  
1256 Teprenone 1  
1257 Tetrazepam 1  
1258 Theobromine 1  
1259 Thiocolchicoside 1  
1260 Tiapride 1  
1261 Tiaprofenic acid 1  
1262 Tiquizium 1  
1263 Tocainide 1  
1264 Trabectedin 1  
1265 Tranilast 1  
1266 Trapidil 1  
1267 Trichlormethiazide 1  
1268 Trimebutine 1  
1269 Trimetazidine 1  
1270 Tropatepine 1  
1271 Troxipide 1  
1272 Urapidil 1  
1273 Valpromide 1  
1274 Vemurafenib 1  
1275 Vindesine 1  
1276 Voglibose 1  
1277 Xylometazoline 1  
1278 Zaltoprofen 1  
1279 Zopiclone 1  

 

 

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