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Office of Inspections and Investigations Also referred to as: OII


Who We Are

OII. We are the frontlines. View the OII Fact Sheet.


The FDA’s Office of Inspections and Investigations (OII) leads all FDA field inspection, investigation, import, emergency response and law enforcement activities to protect America’s public health and safety. In this unique position as FDA’s sole regulatory field operations organization, the real-time evidence and insights observed and collected by OII are essential in empowering the Agency to make unbiased, fact-based regulatory decisions that protect public health.

For more than 100 years, OII has served as the FDA’s premiere field force working to protect the safety of America’s foods, drugs, and medical products.

Vision:

Our global inspections and investigations ensure FDA-regulated products are safe, trusted, and accessible. 

Mission:

We conduct rigorous, transparent, and science-based inspections and investigations, providing real-time evidence and insight essential in empowering fact-based regulatory decisions to protect public health. 

Every 33 minutes of every day, OII initiates an inspection or a regulatory activity


What We Do

OII is at U.S. borders and International Mail Facilities with a footprint across the United States, including Guam and Puerto Rico, and in more than 90 countries, scrutinizing the products U.S. consumers rely upon and ensuring that their production, manufacturing, and importation comply with federal law.

Every year OII employees travel over 26 million miles to conduct FDA operations in the U.S. and abroad.

Our Work 

Inspections identify hazards before they escalate into public health crises. By examining production facilities, imported products, and processes, OII can pinpoint areas of concern and enforce corrective actions to mitigate risks.  

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OII conducts ~30,000 inspections per year, both domestically and internationally, to ensure compliance with FDA regulations in collaboration with our regulatory partners. 
 

Investigations are used to determine and document facts concerning consumer complaints, health fraud, product tampering, and recall compliance.   

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Each year, OII conducts ~10,000 investigations of consumer complaints, fraudulent health products, product tampering, and public health disaster investigations. We are the only federal public health agency with a criminal investigatory enforcement arm, which works with U.S. attorneys, the Department of Justice, Customs and Border Patrol, Drug Enforcement Administration, Federal Bureau of Investigations, and others. 
 

Import operations prevents violative products from entering the domestic market, ensuring that all products regulated by the Food and Drug Administration, whether imported from abroad or produced domestically, meet the same requirements. 

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OII makes over 50 million import admissibility decisions a year and utilizes advanced screening technology to review 100% of FDA-regulated products of foreign origin entering the domestic market.

Emergency Response provides immediate response, ranging from threats to the supply chain, contamination of over-the-counter medicines, to ensuring companies can safely manufacture food, drugs, and medical products after a domestic or international natural disaster. 

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OII manages the FDA Emergency Operations Center, which delivers real-time crisis coordination 24/7, 365 days a year.

To learn more about what each of these functions do, view the Medical Product Inspectorate, Food Product Inspectorate, Imports, Criminal Investigations, and Emergency Response Fact Sheets. 


Who We Partner With 

In pursuit of its mission, OII works with its state, local, tribal, territorial, and foreign counterparts to keep the U.S. food and drug supply safe for consumers. We train and educate our collaborators to support scientific and regulatory expertise.  

Through mutual recognition agreements between the FDA and foreign regulatory authorities, drug investigators rely on information from inspections conducted within one another’s borders.

OII also works with trusted partners on domestic mutual reliance, which enables the FDA and states with comparable regulatory public health systems to rely on, coordinate with, and leverage one another’s work, data, and actions to meet the public health goal of a safe national food supply.  

 




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