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  1. Food and Drug Administration Modernization Act (FDAMA) of 1997

Mercury in Drug and Biologic Products

The information in this list is derived from submissions made by manufacturers+ in response to the agency's call-for-data notices of December 14, 1998 (63 FR 68775), April 29, 1999 (64 FR 23083) and February 3, 2003 (68 FR 5299), the agency's Drug Registration and Listing System, and other agency sources. Products submitted in response to any of the call-for-data notices are preceded by an asterisk (*). The mercury ingredients are abbreviated as TM for thimerosal, PMA for phenylmercuric acetate, PMN for phenylmercuric nitrate, MA for mercuric acetate, MN for mercuric nitrate, MB for merbromin, and MOY for mercuric oxide yellow. The list includes nonhomeopathic human and veterinary drug products and human biological products. Homeopathic drug products are not included because of the low amounts of mercury present in the products. The abbreviation NS under the % column means that the information was "not stated" in the agency's Drug Registration and Listing System.

Thimerosal content for biological products can be found at Thimerosal in Vaccines and  Mercury in Plasma-Derived Products.

+ manufacturers, repackers, relabelers, and distributors

 ManufacturerName of ProductIngredient%
 Akorn Inc.AK Spore Ophthalmic SolutionTM.001
 Akorn Inc.AK Spore HC Ophthalmic Combo DropsTMNS
 Akorn Inc.Fluoracaine Ophthalmic SolutionTMNS
 Akorn Inc.AK Spore HC Otic SuspensionTMNS
*Alcon LaboratoriesProfenal 1% Ophthalmic SolutionTM.005
*Alcon LaboratoriesAdsorbonac 2% Ophthalmic SolutionTM.004
*Alcon LaboratoriesAdsorbonac 5% Ophthalmic SolutionTM.004
 Allergan AmericaOcufen Ophthalmic SolutionTM.005
 Allergan AmericaPoly Pred Ophthalmic SuspensionTM.001
 Allergan Inc.Blephamide SOP Ophthalmic OintmentPMA.0008
 Allergan Inc.Bleph-10 Ophthalmic Ointment 10%PMA.0008
 Allergan Inc.FML SOP Ophthalmic Ointment 0.1%PMA.0008
 Allergan Inc.Poly Pred Ophthalmic SuspensionTM.001
 Altaire PharmaceuticalsNasal Relief 12 Hour SprayPMANS
 American Assn. Retired PersonsOxymetazoline Nasal SprayPMA.002
 American International ChemicalThimerosal (bulk chemical)TM100
 American International ChemicalThimerosal (bulk chemical)TM100
 American International ChemicalThimerosal USP 97% (bulk chemical)TM97
 American Pharmaceutical12 Hour Nasal SolutionPMANS
 Appletree MarketsLong Lasting Nasal SprayPMANS
*Bausch & LombFlurbiprofen Sodium Ophthalmic SolutionTM.005
*Bausch & LombNeomycin & Polymyxin B Sulfates & Gramicidin Ophthalmic SolutionTM.001
*Bausch & LombNeomycin & Polymyxin B Sulfates & Hydrocortisone Otic SuspensionTM.01
*Bausch & LombSulfacetamide Sodium & Prednisolone Sodium Phosphate Ophthalmic Solution 10%/.23%TM.01
*Bristol-Myers SquibbFungizone LotionTM.01
*Bristol-Myers SquibbFungizone CreamTM.01
 C.O. Truxton Inc.Bio-Cot Otic SuspensionTM.01
 C.O. Truxton Inc.Decongest Nasal SprayPMANS
 Cheshire PharmaceuticalOtocort Otic SuspensionTM.01
 Cheshire PharmaceuticalOcutricin Ophthalmic SolutionTM.01
 Cheshire PharmaceuticalSulfapred Ophthalmic SolutionTMNS
 CVSNasal Spray PumpPMANS
 CVS Revco DS Inc.12 Hour Decongestant Pump Nasal SprayPMANS
 Dolder Ltd.Thimerosal (bulk chemical)TM100
 Dorex International Corp.Long Acting Nasal SprayPMA.002
 Drug Guild DistributorsLong Acting Nasal Spray Kolex LAPMA.002
 DRX PharmaceuticalBlephamide Ophthalmic OintmentPMANS
 DRX PharmaceuticalCortisporin Ophthalmic SuspensionTM.001
 DRX PharmaceuticalNeomycin Polymyxin B Sulfates Hydrocortisone Ophthalmic SuspensionTMNS
 DRX PharmaceuticalNeomycin Polymyxin B Hydrocortisone Otic SuspensionTM.01
 DRX PharmaceuticalNeomycin Polymyxin B Gramicidin Ophthalmic SolutionTM.01
 DRX PharmaceuticalVasocidin Ophthalmic SolutionTMNS
 DRX PharmaceuticalColymycin S Otic SuspensionTM.002
 DRX PharmaceuticalPediotic Otic SuspensionTMNS
 Dysers SalThimerosal (bulk chemical)TMNS
 Family Independent Pharmacy12 Hour Nasal Decongestant SprayPMANS
 Family Independent PharmacyLong Acting Nasal SprayPMANS
 Farm Fresh Inc.Hemorrhoid Relief OintmentPMN.01
 Fays Drug Services12 Hour Nasal Spray PumpPMANS
 Federated FoodsLong Acting Nasal SprayPMA.002
 Fleming Companies12 Hour Nasal SprayPMA.002
 Foxmeyer Drug Co.Nasal Spray PumpPMANS
 Global SourceNasin Long Acting Nasal SprayPMANS
 Harco DrugMercurochrome Aqueous SolutionMB2
 Harris-TeeterOxymetazoline Nasal SprayPMA.002
 Hi Tech Pharmacal Co.Long Acting Nasal SprayPMA.002
 Hudson Corp.Nasal Spray Extended ReliefPMANS
 Hurst PharmaceuticalDuomycin-HC Otic SuspensionTM.01
 K and B DistributorsMercurochrome Aqueous SolutionMB2
*King PharmaceuticalsCortisporin Ophthalmic SuspensionTM.001
*King PharmaceuticalsNeosporin Ophthalmic SuspensionTM.001
*King PharmaceuticalsViroptic Ophthalmic SolutionTM.001
 King PharmaceuticalsNeomycin Polymyxin B Sulfates Hydrocortisone Otic SuspensionTMNS
*King PharmaceuticalsPediotic SuspensionTM.001
*King PharmaceuticalsCortisporin Otic SuspensionTM.01
 KinrayOxymetazoline Nasal SprayPMA.002
 Laboratori DerivatiAdrenal Cortex InjectionTM.01
 Leader12 Hour Nasal SprayPMANS
 LeaderNasal Pump SprayPMANS
 LS Raw Materials Ltd.Mercurochrome NF 12 100% (bulk chemical)MB100
 Major PharmaceuticalsCortomycin Ophthalmic SuspensionTMNS
 Major PharmaceuticalsSulfacetamide Sodium & Prednisolone Sodium Phosphate Ophthalmic SolutionTM.01
 Major PharmaceuticalsCortomycin Otic SuspensionTM.01
 Major PharmaceuticalsNeocidin Ophthalmic SolutionTM.01
 Martin Surgical SupplyTestosterone Injection Suspension 50 mgTM.008
 Martin Surgical SupplyTestosterone Injection Suspension 100 mgTMNS
 Mays Drug StoresHemorrhoid Relief OintmentPMN.01
 Medalist LaboratoriesLong Lasting Nasal Spray PumpPMANS
 Meyers Supply Inc.Long Acting Nasal SprayPMA.002
 NavressoLong Acting Nasal SprayPMANS
 Omicron Quimica SAThimerosal USP 97% (bulk chemical)TM97
 Parade (Grocer's Supply)Oxymetazoline Nasal SprayPMA.002
*Parkedale PharmaceuticalsColy-Mycin S Otic SuspensionTM.002
 Pay N Save Corp.Decongestant Nasal SprayPMANS
 PharmedixBleph 10 Ophthalmic Solution 10%TM.005
 PharmedixViroptic Ophthalmic Solution 1%TM.001
 PharmedixBlephamide Ophthalmic OintmentPMANS
 PharmedixTriple Antibiotic Ophthalmic SolutionTM.01
 PharmedixColymycin S Otic SolutionTM.002
 PharmedixNeo Poly with HC Otic SuspensionTM.01
 Physicians Total Care Inc.Neomycin Polymyxin B Sulfates Hydrocortisone Ophthalmic SuspensionTMNS
 Physicians Total Care Inc.Viroptic Ophthalmic SolutionTM.001
 Physicians Total Care Inc.Cortisporin Ophthalmic SuspensionTM.001
 Physicians Total Care Inc.Ocufen Ophthalmic SolutionTM.0005
 Physicians Total Care Inc.Vasocidin Ophthalmic SolutionTMNS
 Ping On Ointment Co. Ltd.Ping On Topical OintmentMercuryNS
 Prime Natural Health12 Hour Nasal SprayPMANS
 Primedics LaboratoriesTesterone Injection Suspension 50 mgTM.008
 Publix Inc.Long Acting Nasal SprayPMANS
 Publix SupermarketsLong Acting Decongestant Nasal SprayPMANS
 Qualitest PharmaceuticalsNasal Spray SolutionPMANS
 Qualitest PharmaceuticalsAntibiotic HC Otic SuspensionTMNS
 RDS Acquisition Corp.12 Hour Nasal SprayPMANS
 Republic Drug Co.12 Hour Nasal SprayPMA.002
*Schering-Plough Animal HealthGentocin Durafilm Ophthalmic Solution (for dogs only)PMN.002
 Scrivner, Inc.Hemorrhoid Relief OintmentPMN.01
 Sight PharmaceuticalsNeomycin Polymyxin B Sulfates Hydrocortisone Otic SuspensionTMNS
 Sight PharmaceuticalsSulfacetamide Sodium & Prednisolone Sodium Phosphate Ophthalmic SolutionTM.01
 Spectrum Quality ProductsMerbromin (bulk chemical)MB100
 Spectrum Quality ProductsMercuric Oxide Yellow (bulk chemical)MOY100
 Spectrum Quality ProductsThimerosal (bulk chemical)TM100
 Spectrum Quality ProductsThimerosal (bulk chemical)TM100
 Super LaboratoriesLong Acting Nasal SprayPMANS
*Taro PharmaceuticalsTaro Nasal Decongestant SprayPMA.002
 Teral LaboratoriesOticin HC Otic SuspensionTM.01
 Thames Pharmacal Co.12 Hour Nasal SprayPMANS
 Thrifty Payless Inc.Nasal Spray Pump FormulaPMANS
 Thrifty Payless Inc.Decongestant Nasal Spray PumpPMANS
 United Research LabsAntibiotic Ear SuspensionTM.01
 United Research LabsNeomycin Polymyxin B Sulfates Gramicidin Ophthalmic SolutionTM.01
 US OphthalmicsFluorescein Sodium Ophthalmic SolutionTMNS
 US OphthalmicsSulf-10 Ophthalmic SolutionTMNS
 US OphthalmicsVasocidin Ophthalmic SolutionTMNS
 US OphthalmicsPhenylephrine HC1 Ophthalmic Solution 10%TMNS
 USCO LogisticsProcofen Ophthalmic SolutionTM.005
 USCO LogisticsProfenal Ophthalmic SolutionTM.005
 VEDCO Inc.Tribiotic Ophthalmic SolutionTMNS
 Waldbaum Inc.Hemorrhoidal OintmentMNNS
 Weeks and Leo Co. Inc.Long Acting Nasal Spray SolutionPMA.002
*Whitehall-RobinsDristan 12-Hour Nasal SprayTM.002

Date created: August 5, 2003; updated June 13, 2006.

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