| A Comprehensive Simulation Analysis of TMB Estimation by Targeted Oncology Panels |
Dan Li, Binsheng Gong, Yifan Zhang, Joshua Xu |
Dan.Li@fda.hhs.gov |
| A General Statistical Framework for Exploring FAERS |
Wang Dong, Zhiyuan Lu |
Zhiyuan.Lu@fda.hhs.gov |
| A Novel Natural Language Processing and Machine Learning Classifier that Streamlines Extracting Drug-Adverse Event Data from Literature Reports |
Alfred Sorbello, Rashed Hasan, Henry Francis, Isaac Chang, Mitra Ahadpour, Max Laponsky, Jeremy Walsh, Caroline Trier |
Alfred.Sorbello@fda.hhs.gov |
| A Showcase of HIVE RNAseq Pipeline - Identifying Molecular Features of Neural Stem Cells in Varied Differentiation Stages |
Sydney Fenstermaker, Ge Ma, Viswanadham Sridhara, Wei-Lun Alterovitz, Ilya Mazo, Luis Santana-Quintero, Brent McCright |
Sydney.Fenstermaker@fda.hhs.gov |
| An Automated AI Tool for the Analyses of Phase I, II, III Clinical Trials to Identify Pharmacokinetics Anomaly |
Md Nayeem Hossain, Gunjan Gugale, Le Wang, Peter Lee. |
Mdnayeem.Hossain@fda.hhs.gov |
| An Overview of the Office of Computational Science Core DataFitness Service |
Tejas Patel, David Jacobs, Qingying Lu, Kathryn Matto, Jamal Horne, Janie Ma |
David.Jacobs@fda.hhs.gov |
| Characterization of the Immune-Driven Drug Hypersensitivity by Single-Cell RNA Sequencing Technologies |
Masahide Yano, Marco Cardone, Krizia Chambers, Viswanadham Sridhara, Mike Mikailov, Montserrat Puig, Michael Norcross |
Masahide.Yano@fda.hhs.gov |
| CIRDS: CTP Integrated Research Data System |
Mark Gingrass, Vibha Kumar, Christine Wang, Wei Chen, Geetha Potluri, Alex Abramson, Nirmala Uralikrishna, Wei Wu |
Mark.Gingrass@fda.hhs.gov
Wei.Chen1@fda.hhs.gov
Geetha.Potluri@fda.hhs.gov |
| Computational Pipeline Engine in FDA HIVE: Adventitious Agent Detection from NGS Data |
Ilya Mazo, Alexander Lukyanov, Anton Golikov, Luis Santana- Quintero |
Ilya.Mazo@fda.hhs.gov |
| Data Scaling for Efficient Processing on HPC Clusters |
Mike Mikailov, Weijie Chen, Weizhe Li, Nicholas Petrick, Fu-Jyh Luo, Stuart Barkley, Dillip Emmanuel, Rusif Eyvazli |
Mike.Mikailov@fda.hhs.gov |
| Developing Risk Assessment Applications at the FDA using AWS (Amazon Web Services) |
Hong Yang, Yin Huang, Richard Forshee, Mark Walderhaug, Jason Claeys, Rebecca Kahn, Leslie Eberhardt, Guangfan Zhang |
Rebecca.Kahn@fda.hhs.gov |
| D-VIDE: A Dashboard for Visualizing Infectious Disease Epidemiology and its Applications to COVID-19 for Local Counties |
Osman N. Yogurtcu, Artur A. Belov, Richard A. Forshee, Carolyn A Wilson |
Osman.Yogurtcu@fda.hhs.gov |
| Elucidating Interactions Between SARS-CoV-2 Trimeric Spike Protein and ACE2 Using Homology Modeling and Molecular Dynamics Simulations |
Sugunadevi Sakkiah, Huixiao Hong |
Suguna.Sakkiah@fda.hhs.gov |
| Enterprise Business Data Analytics (EBDA) Platform – FDA’s Multifaceted Shared Federated Analytical Ecosystem |
Swati Kulkarni, Will Stevenson |
Swati.Kulkarni@fda.hhs.gov
Karthikeyan.Murugesan@fda.hhs.gov
Rajesh.Sripada@fda.hhs.gov |
| Evaluating the Utility of Computational and Cheminformatic Analyses to Screen for Potential Toxicological Hazard of Flavor Compounds Relevant to Tobacco Products |
Reema Goel, Luis G. Valerio, Jr. |
Reema.Goel@fda.hhs.gov |
| Exploring the Application of Informatics Tools to Visualize the Chemical Space of Compounds Released from Medical Devices |
Candice J. Gordon, Keaton Nahan, Diego Rua, Robert M. Elder |
Robert.Elder@fda.hhs.gov |
| Genome Analysis Toolkit (GATK) Pipeline Programming Platform on HPC Cluster |
Xiaoqing (Janet) He, Pamela Callier, Elvia Butler |
Xiaoqing.He@fda.hhs.gov |
| geoMapr : An Analytic Dashboard for Prescription Drug Utilization with Geographically Referenced Data Enrichment and Machine Learning |
Meilan Chen, Jaejoon Song, Yueqin Zhao, Yong Ma, Rose Radin, Grace Chai,
Shekhar Mehta, Travis Ready, Corinne Woods, Saranrat Wittayanukorn |
JaeJoon.Song@fda.hhs.gov |
| Project Description and Pilot Study for a Pathologist-Annotated AI/ML Validation Dataset |
Sarah N Dudgeon, Si Wen, Matthew Hanna, Rajendra Gupta,Mohamed Amgad,Manasi Sheth,Hetal Marble,Richard Huang,Cliff Szu,Darick Tong,Bruce Werness,Denis Larsimont,Anant Madabhushi,Evangelos Hytopoulos,Raj Singh,Steven Hart,Joel Saltz,Roberto Salgado,Brandon D Gallas |
Sarah.dudgeon@yale.edu
brandon.gallas@fda.hhs.gov |
| How the Office of Innovation Supports Scientists |
Federico Grau, Nacinader Melo, Irving Reeves, Eric Reinhold, Rilwan Sogbesan, John Spafford, Rebecca Thomas, Allen Vuong |
OIMScientificIT@fda.hhs.gov |
| Crowdsourcing Advances Reproducibility Standards and Biomarker Development |
Holly Stephens, Elaine Johanson, Emily Boja, Yuriy Gusev, Krithika Bhuvaneshwar, Subha Madhavan, Jonathon Keeney, Hadley King, Janisha Patel, Raja Mazumder, Sean Watford, Ezekiel Maier |
Sarah.Stephens@fda.hhs.gov
Ezekiel.Maier@fda.hhs.gov |
Power Analysis and Data Augmentation for
Real World Evidence with Uncertain Genetic Information |
Wei (Vivian) Zhuang, Joshua Xu |
Wei.Zhuang@fda.hhs.gov |
| Preliminary Investigative Analysis of Flavor Compounds Crossing Blood-Brain Barrier Using Computational Models |
Kim Stratford, Sheila Healy, Alex Tu, Luis G. Valerio Jr. |
Kimberly.Stratford@fda.hhs.gov |
| Novel Statistical Approaches for Leveraging Real-World Data to Support Regulatory Decisions |
Wei-Chen Chen, Heng Li, Nelson Lu, Changhong Song, Ram Tiwari, Chenguang Wang, Yunling Xu, Lilly Yue |
Wei-Chen.Chen@fda.hhs.gov |
| Real-World Evidence Synthesis on the Sex-related Modifying Effects on Development of Periprosthetic Osteolysis in Hip Arthroplasty |
Wei-Lun Alterovitz, John Dougherty, Elaine Thompson, Hussein Ezzeldin, Luis Santana- Quintero, Mark O Walderhaug, Richard Forshee, Yelizaveta Torosyan |
Wei-Lun.Alterovitz@fda.hhs.gov
John.Dougherty1@fda.hhs.gov |
| RNA-seq Differential Expression (DE) Toolkit |
Alexis Norris, Mamatha Garige, Fu-Jyh Luo, Mike Mikailov, Nicholas Petrick, Heather Lombardi, Mayumi Miller |
Alexis.Norris@fda.hhs.gov |
| Scalnet: Scalable Network Estimation with L0 Penalty |
Junghi Kim, Hongtu Zhu, Xiao Wang, Kim-Anh Do |
Junghi.Kim@fda.hhs.gov |
| Secure Platforms for Distributed RWE-based Clinical Studies |
Ryan Weil, Magizhan Tamilarasu, Angela Carrigan, Chetan Paul |
Chetan.Paul@fda.hhs.gov |
| Single Cell RNA-Seq Analyses to Investigate Sub-Populations of Bone-Marrow and Adipose Derived Multipotential Stromal Cells (MSCs) from Three Donors |
Furtak Vyacheslav, Viswanadham Sridhara, Malcolm Moos |
Vyacheslav.Furtak@fda.hhs.gov
Malcolm.Moos@fda.hhs.gov |
| Statistical Comparisons of Product Quality Comparability |
Michael Daniel Lucagbo, Tianjiao Dai, Yixin Ren, Meiyu Shen, Yi Tsong |
Tianjiao.Dai@fda.hhs.gov |
| The Global Substance Registration System (GSRS): An Agency-Wide System for Organizing Scientific and Regulatory Data within the FDA and Throughout the World |
Lawrence Callahan, Tyler Peryea, Frank Switzer, Elaine Johanson, Samir Lababidi, Archana Newatia, Niko Anderson Daniel Katzel, Noel Southall, Sarah Stemann |
Lawrence.Callahan@fda.hhs.gov |
| The National Evaluation System for Health Technology Coordinating Center (NESTcc) – Key Learnings in Enhancing the Access to Generate Real-World Evidence (RWE) for Medical Devices |
Dure Kim, Keondae Ervin, Tiffany Abushaikha, Daniel A. Caños, Jose (Pablo) Morales, Flora S. Siami, Robbert Zusterzeel |
dkim@mdic.org
Robbert.Zusterzeel@fda.hhs.gov |
| Towards Automated Species Identification of Food Contaminating Beetles Through Elytral Pattern Recognition |
Tanmay Bera, Leihong Wu, Hongjian Ding, Halil Bisgin, Zhichao Liu, Amy Barnes, Monica Pava-Ripoll, Himansu Vyas, Weida Tong, Joshua Xu |
Tanmay.Bera@fda.hhs.gov |
| Potential Blood Transfusion Adverse Events Can be Found in Unstructured Text in Electronic Health Records Using Natural Language Processing Tools |
Roselie A Bright,
Summer K Rankin, Katherine Dowdy, Serge Blok, Susan J. Bright-Ponte, Lee Anne Palmer |
Roselie.Bright@fda.hhs.gov
Rankin_Summer@bah.com
Susan.Bright@fda.hhs.gov
LeeAnne.Palmer@fda.hhs.gov |
| New and Increasing Rates of Adverse Events Can be Found in Unstructured Text in Electronic Health Records using Natural Language Processing Tools |
Roselie A Bright, Katherine Dowdy, Summer K Rankin, Serge Blok, Lee Anne Palmer, Susan J. Bright-Ponte |
Roselie.Bright@fda.hhs.gov
Dowdy_Katherine@bah.com
LeeAnne.Palmer@fda.hhs.gov
Susan.Bright@fda.hhs.gov |
| Use of Ontologies, Such as UNII, to Link Within and Across Data Sources |
David Milward, Matt Garber, Nicolas Joannin, Qais Hatim |
Qais.Hatim@fda.hhs.gov |
| Visualizing Historical Changes to the Bacteriological Analytical Manual (BAM) |
Pamela Mesite |
Pamela.Mesite@fda.hhs.gov |
| Using Gibbs Sampling and Data Augmentation to Compare Diagnostic Tests in RWE Studies with Extreme Verification Bias |
Gene Pennello, Qin Li |
Gene.Pennello@fda.hhs.gov
Qin.Li@fda.hhs.gov |
| Using Machine Learning on ICD-10 Data to Enhance an Expert Anaphylaxis Case Definition |
Kamil Can Kural, Ilya Mazo, Mark Walderhaug, Lei Huang, Luis Santana-Quintero and Ravi Goud |
Kamil.Kural@fda.hhs.gov
Ravi.Goud@fda.hhs.gov |
