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  4. 2023 FDA & ASCPT Annual William B. Abrams Lecture: Mechanistic Studies in Drug Metabolism and Single Cell Biology to Advance Clinical Pharmacology - 05/30/2023
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Other | Virtual

Event Title
2023 FDA & ASCPT Annual William B. Abrams Lecture: Mechanistic Studies in Drug Metabolism and Single Cell Biology to Advance Clinical Pharmacology
May 30, 2023

May 30, 2023
1:00 PM - 2:30 PM ET
2023 FDA & ASCPT Annual William B. Abrams Lecture


The FDA has collaborated with American Society for Clinical Pharmacology and Therapeutics (ASCPT) since 1999 to design and implement the William B. Abrams Lecture, a joint annual educational initiative between ASCPT and FDA.  Dr. Abrams was an FDA special government employee who established the Center for Drug Evaluation and Research’s (CDER's) Staff College and continuing professional education program.  Dr Abrams provided the foundation for FDA’s strong tradition of high quality scientific education. 

The William B. Abrams Lecture curriculum is currently planned by ASCPT and Committee for the Advancement of Clinical and Scientific Education (CACSE), an FDA-wide clinically focused educational group that addresses Agency-wide clinical and therapeutic educational needs with respect to cutting- edge technologies and advancements.

Goals and Objectives

The FDA and ASCPT wish to honor Dr. Abrams' many professional contributions to ASCPT, including years of service as a distinguished clinical scientist and Society officer, in which he served as president from 1975 to 1976. The FDA and ASCPT jointly sponsor an educational lecture for the benefit of FDA health professionals and scientists to discuss the cutting-edge technologies and therapeutic advances in various scientific and clinical areas. This lecture will be open to the interested public. 

The annual William B. Abrams Lectureship is intended for FDA regulatory review and research staff as well as interested members of the scientific and clinical community at large.

About the Speaker:

Dr. Namandjè N. Bumpus, FDA Chief Scientist
U.S. Food and Drug Administration

Dr. Namandjé N. Bumpus serves as the FDA Chief Scientist. She provides strategic leadership and expertise to support scientific excellence, innovation, collaboration, and capacity to achieve FDA's public health mission.  Prior to joining the FDA, Dr. Bumpus served as faculty at Johns Hopkins University School of Medicine for 12 years, most recently as the E.K. Marshall and Thomas H. Maren Professor and Chair of the Department of Pharmacology and Molecular Sciences.  She also served previously as Associate Dean for Basic Research. Dr. Bumpus’ research expertise is in pharmacology with a particular focus on drug metabolism, pharmacogenetics, bioanalytical chemistry, and infectious disease.  She earned a B.A. in Biology at Occidental College in 2003, a Ph.D. in Pharmacology at the University of Michigan in 2007 and completed a postdoctoral fellowship in molecular and experimental medicine at The Scripps Research Institute in La Jolla, CA in 2010. 

Dr. Bumpus currently serves as President-elect of the American Society for Pharmacology and Experimental Therapeutics (ASPET).  She previously served as Chair of the NIH Xenobiotic and Nutrient Disposition and Action Study Section. Dr. Bumpus is an elected fellow of the American Association for the Advancement of Science (AAAS) and member of the National Academy of Medicine.

About the Presentation:

This presentation will focus how mechanistic drug metabolism studies and single cell proteomics can be used to inform clinical pharmacology, particularly in the context of understanding inter-individual variability. 
Learning Objectives:

  • Identify specific pathways of drug metabolism and how drug metabolism can contribute to heterogeneity
  • Discuss the ways that single cell approaches can be leveraged and employed to enhance insight into pharmacology

Watch Recorded Webcast:

FDA/ASPT Annual Abrams Lecture- Mechanistic Studies in Drug Metabolism and Single Cell Biology to Advance Clinical Pharmacology
Dr. Namandjè Bumpus, FDA Chief Scientist

Contact: Rokhsareh.Shahidzadeh@fda.hhs.gov for more information.

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