FDA Update on Post-market Assessment of Chemicals in the Food Supply
Constituent Update
August 19, 2025
Today, the U.S. Food and Drug Administration (FDA) updated its list of select chemicals currently under the agency’s review to provide more insight on the status of the FDA’s post-market assessments of chemicals in the food supply. The agency first published a list in July 2023 and updated it in March 2024. FDA will continue to update the list periodically.
This updated list includes select food ingredients (including food additives and color additives), food contact substances, and contaminants under FDA review. The list now includes the date the FDA’s review was initiated, the date of the most recent risk management action, and links for the public to provide input (where applicable).
The chemicals new to this updated list are: butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), azodicarbonamide (ADA), FD&C Blue No. 1, FD&C Blue No. 2, FD&C Green No. 3, FD&C Red No. 40, FD&C Yellow No. 5, and FD&C Yellow No. 6. We are also reviewing the presence of opiate alkaloids on poppy seeds. To facilitate our post-market scientific assessments of BHA, BHT, and ADA, we intend to seek data and information from stakeholders in the near future. In addition, lead as a food contact substance has been separated from lead as a contaminant and is being given its own entry on the updated list. The FDA is also taking steps to expedite its review of chemicals included in previous updates like phthalates, propylparaben, and titanium dioxide.
This post-market review effort is part of a larger initiative to improve food chemical oversight.
Additional Information
- List of Select Chemicals in the Food Supply Under FDA Review
- Food Chemical Safety
- FDA Advances Robust, Transparent Post-Market Chemical Review Program to Keep Food Supply Safe and Healthy
- Conversations with Experts: FDA Works to Enhance the Assessment of Ingredients in Foods and Food Contact Substances on the Market
- FDA Voices Blog: How FDA’s New Approach to Reviewing Chemicals Added to Food Will Strengthen Food Safety