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  6. In the GI Tract
  1. Drug Interactions & Labeling

In the GI Tract

  • Sucralfate, some milk products, antacids, and oral iron preparations
  • Omeprazole, lansoprazole, H2-antagonists
  • Didanosine (given as a buffered tablet)
  • Cholestyramine


  • Block absorption of quinolones, tetracycline, and azithromycin
  • Reduce absorption of ketoconazole, delavirdine
  • Reduces ketoconazole absorption
  • Binds raloxifene, thyroid hormone, and digoxin


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