U.S. flag An official website of the United States government
  1. Home
  2. Drugs
  3. Development & Approval Process (Drugs)
  4. Development Resources
  5. Drug Interactions & Labeling
  6. Cytochrome P450 3A
  1. Development Resources

Cytochrome P450 3A

Cytochrome P450 3A

  • Responsible for metabolism of:
    • Most calcium channel blockers
    • Most benzodiazepines
    • Most HIV protease inhibitors
    • Most HMG-CoA-reductase inhibitors
    • Cyclosporine
    • Most non-sedating antihistamines
    • Cisapride
  • Present in GI tract and liver

 

 

Back to Learning Module