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  3. Development & Approval Process | Drugs
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  5. Drug Interactions & Labeling
  6. Cytochrome P450 2C9
  1. Drug Interactions & Labeling

Cytochrome P450 2C9

  • Absent in 1% Caucasians and African-Americans

  • Primary metabolism of:

    • Most NSAIDs (including COX-2)

    • S-warfarin (the active form)

    • Phenytoin

  • Inhibited by:

    • Fluconazole

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