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  6. Cytochrome P450 2C19
  1. Drug Interactions & Labeling

Cytochrome P450 2C19

  • Absent in 20–30% of Asians, 3–5% Caucasians
  • Primary metabolism of:
    • Diazepam
    • Phenytoin
    • Omeprazole
  • Inhibited by:
    • Omeprazole
    • Isoniazid
    • Ketoconazole

 

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