U.S. flag An official website of the United States government

On Oct. 1, 2024, the FDA began implementing a reorganization impacting many parts of the agency. We are in the process of updating FDA.gov content to reflect these changes.

  1. Home
  2. Drugs
  3. Development & Approval Process | Drugs
  4. Development Resources
  5. Drug Interactions & Labeling
  6. Cytochrome P450 1A2
  1. Drug Interactions & Labeling

Cytochrome P450 1A2

  • Induced by smoking tobacco
  • Catalyzes primary metabolism of:
    • Theophylline
    • Imipramine
    • Propranolol
    • Clozapine
  • Inhibited by:
    • Many fluoroquinolone antibiotics
    • Fluvoxamine
    • Cimetidine

 

Back to Learning Module

Back to Top