Animal & Veterinary

Current Animal Food GRAS Notices Inventory

The following table is provided on an interim basis, until the Animal Food GRAS Notices Inventory database is launched. The data provided are current through 11/13/2018. A decision on FDA's part to file a submission as a GRAS notice has not reflected our judgment as to whether the notice addressed all issues or discussed all critical data or information.

Persons using assistive technology may not be able to fully access information in the submissions. For assistance, please call 240-402-7002.

AGRN (select AGRN No. for detailed record) Notifier Substance Intended Use   Intended Species Date of Filing  FDA's Letter (select to view letter)
1
(PDF - 387 pages)
 
Resonant Biosciences, Inc. Chlorine dioxide To be used as a processing aid, with a maximum application rate of 55 ppm per batch, in the production of non-food grade ethanol, food grade ethanol, and distillers grains for animal feed use for food-producing animals. Food-producing animals.  12/21/2010 Notice does not provide a basis for a GRAS determination (PDF - 6 pages)
2 Lallemand Specialties Inc., doing business as Lallemand Ethanol Technology Penicillin G potassium To control the levels of contaminants and their by-products in the production of non-food grade and food grade ethanol and distillers grain for target animal feed use at a level not to exceed 6 ppm of commercial product or 2.7 ppm of penicillin G potassium, in the fermentor. Beef cattle, dairy cows, broiler chickens, egg-laying chickens, swine, and sheep. Pets including dogs, cats, rabbits, guinea pigs and horses.  12/23/2010 At notifier's request, FDA ceased to evaluate the notice. (PDF - 2 pages)
3
(PDF - 160 pages)
 
Hill’s Pet Nutrition Inc. alpha-Lipoic acid To be used as an ingredient in dry foods for adult dogs at levels up to 150 ppm (150 mg/kg food or 0.0150%) as a cellular antioxidant and cofactor of enzymes involved in the metabolism of carbohydrates and amino acids. Adult dogs (i.e., at least 1 year old). 2/8/2011 Notice does not provide a basis for a GRAS determination (PDF - 5 pages)
4 Lallemand Specialties Inc., doing business as Lallemand Ethanol Technology Virginiamycin To be used as a processing aid in the production of non-food grade and food grade ethanol at a level not to exceed 6 ppm of commercial product (3 ppm virginiamycin) in the fermentor. Beef cattle, dairy cows, broiler chickens, egg-laying chickens, swine, and sheep. Pets including dogs, cats, rabbits, guinea pigs and horses. 3/16/2011 At notifier's request, FDA ceased to evaluate the notice. (PDF - 2 pages)
5
(PDF - 67 pages)
 
Emerald Carolina Chemicals LLC Hydrophobic silica As a defoaming component of a defoamer used in the removal of oil from condensed distillers solubles, at levels up to 20 ppm. Beef cattle, dairy cattle, poultry (turkey, broiler chickens,
and egg laying hens), sheep, goats, and swine.
 
5/12/2011 FDA has no questions. (PDF - 3 pages)
6
(PDF - 57 pages)
 
Emerald Carolina Chemicals LLC Polyethylene glycol (400) dioleate As an emulsifier component of a defoamer used in the removal of oil from condensed distillers, at levels up to 64 ppm. Beef cattle, dairy cattle, poultry (turkey, broiler chickens,
and egg laying hens), sheep, goats, and swine.
 
5/12/2011 FDA has no questions. (PDF - 3 pages)
7
(PDF - 101 pages)
 
Emerald Carolina Chemicals LLC Polyoxyethylene (20) sorbitan monostearate (polysorbate 60) As an emulsifier component of a defoamer used in the removal of oil from condensed distillers solubles, at levels up to 20 ppm. Beef cattle, dairy cattle, poultry (turkey, broiler chickens,
and egg laying hens), sheep, goats, and swine.
 
5/12/2011 FDA has no questions. (PDF - 3 pages)
8
(PDF - 21 pages)
 
Rubinum S.A. Animal Health Bacillus cereus variant toyoi To be used as an animal feed ingredient to help maintain the animal's gut microflora. Swine, cattle, broiler chickens, turkeys, and rabbits. 6/10/2011 Notice does not provide a basis for a GRAS determination. (PDF - 4 pages)
9
(PDF - 82 pages)
 
Vitamin Derivatives, Inc. 1-alpha-Hydroxycholecalciferol To be used as a dietary source of vitamin D up to 5 micrograms per kilogram in the finished feed. Broiler chickens. 7/13/2011 Notice does not provide a basis for a GRAS determination. (PDF - 6 pages)
10
(PDF - 61 pages)
 
Gevo Inactivated modified Saccharomyces cerevisiae As a component of animal feed when used in the fermentation and distillation of corn to produce isobutanol. Beef cattle, dairy cows, broiler chickens, egg-laying chickens, swine, sheep, dogs, cats, rabbits, guinea pigs and horses. 8/25/2011 Notice does not provide a basis for a GRAS determination. (PDF - 4 pages)
11 Lallemand Specialties Inc., doing business as Lallemand Ethanol Technology Penicillin G potassium To control the levels of contaminants and their byproducts in the production of food grade and no-food grade ethanol and distillers grain for target animal feed use at a level not to exceed 6 ppm of commercial product, or 3.0 ppm of Penicillin G in the fermentor. Beef cattle, dairy cows, broiler chickens, egg-laying chickens, swine and sheep. Pets including dogs, cats, rabbits, guinea pigs and horses. 9/15/2011 At notifier's request, FDA ceased to evaluate the notice. (PDF - 2 pages)
12 Lallemand Specialties Inc., doing business as Lallemand Ethanol Technology Virginiamycin To be used as a processing aid in the production of food and non-food grade ethanol at a level not to exceed 6 ppm of commercial product (3 ppm Virginiamycin) in the fermentor. Beef cattle, dairy cows, broiler chickens, egg-laying chickens, swine, and sheep. Pets including dogs, cats, rabbits, guinea pigs and horses. 9/15/2011 At notifier's request, FDA ceased to evaluate the notice. (PDF - 2 pages)
13 Gevo Isobutanol distillers grain To be used as a component of animal feed. Beef cattle, dairy cows, broiler chickens, egg-laying chickens, swine and sheep. Pets include: dogs, cats, rabbits, guinea pigs, and horses. 9/29/2011 At notifier's request, FDA ceased to evaluate the notice. (PDF - 2 pages)
14
(PDF - 576 pages)
DSM Nutritional Products Phytase enzyme produced by an Aspergillus oryzae strain expressing a synthetic gene coding for a 6-phytase from Citrobacter braakii To increase the digestibility of phytin-bound phosphorous or to increase phosphorous availability from phytate in poultry diets when fed at the rate of 250-4000 FYT/kg feed. Poultry (turkey, broiler chickens, and egg laying hens) 11/14/2012  FDA has no questions. (PDF - 3 pages)

15
(PDF - 505 pages)

DSM Nutritional Products Phytase enzyme produced by an Aspergillus oryzae strain expressing a synthetic gene coding for a 6-phytase from Citrobacter braakii To increase the digestibility of phytin-bound phosphorous or to increase phosphorous availability from phytate in swine diets when fed at the rate of 500-4000 FYT/kg feed. Swine 8/8/2013 FDA has no questions. (PDF - 3 pages)
16
(PDF - 87 pages)
 
Metabolic Explorer L-methionine 85% produced by a bioengineered Escherichia coli K-12 Nutrient at levels up to 0.3% in animal feed All animals 1/3/2014 FDA has no questions. (PDF - 4 pages)
17
(PDF - 170 pages)
 
DSM Nutritional Products Canthaxanthin To be used in breeder hen diets at the rate of 6 mg /kg of feed as a nutritive antioxidant to support the development of chicks. Breeder hens used for hatching egg production. 7/22/2014 FDA has no questions. (PDF - 4 pages)
18 DSM Innovation, Inc.
BioProducts & Services Division
Inactivated modified Saccharomyces cerevisiae As a component of animal feed when used in the fermentation of corn to produce ethanol. Poultry (broilers, layers, breeding chickens and turkeys), swine (piglets, growers, finishers, gestating and lactating sows), bovines (beef and dairy), fish (salmonoids, catfish, and tilapia), minor species (ducks, quail, sheep and goats) and pets. 12/22/2014 At notifier’s request, FDA ceased to evaluate the notice. (PDF - 2 pages)
19
(PDF - 123 pages)
Freedom Health L.L.C. L-Glutamine Utility information not evaluated for GRAS, see FDA’s letter for more information. Post-weaning horses. 3/22/2016 FDA has no questions.
(PDF - 3 pages)
20
(PDF- 899 pages)
DSM Innovation, Inc.
BioProducts & Services Division
Inactivated modified Saccharomyces cerevisiae As a component of animal feed when used in the fermentation of corn to produce ethanol. Pets, poultry (broilers, layers and breeding chickens; turkeys), swine (piglets, growers, finishers, gestating and lactating sows), bovine (beef and dairy), fish (salmonoids, catfish, tilapia), and minor species such as ducks, quail, sheep, and goats. 4/29/2016 FDA has no questions. (PDF - 4 pages)
21
(PDF – 598 pages)
Agrivida, Inc. Ground grain obtained from a corn (Zea mays) variety that expresses an altered appA 6-phytase gene obtained from Escherichia coli strain K12 To increase the digestibility of phytin-bound phosphorous or to increase phosphorous availability from phytate in poultry feeds when used at a rate of 75 g to 1.7 kg per ton of complete feed and providing 250-6000 phytase units (FTU)/kg complete feed. Poultry 7/28/2016 FDA has no questions. (PDF – 4 pages)
22
(PDF – 86 pages)
Royal Canin U.S., Inc. Marigold extract To be used in food and treats for dogs and cats at a level sufficient to provide no more than 5 mg lutein per 1000 kcal metabolizable energy (ME) as a nutritive antioxidant. Dogs and cats 8/3/2016 Notice does not provide a basis for a GRAS determination. (PDF – 4 pages)
23 Aker BioMarine Antarctic Euphausia superba (krill) meal To be used as a source of protein and lipid in food for adult dogs at a maximum inclusion level of 3% by weight of dry food. Adult dogs 01/06/2017 At notifier’s request, FDA ceased to evaluate the notice. (PDF- 1 page)
24 (PDF - 194 pages) CJ CheilJedang Corporation L-methionine 90% produced by a bioengineered Escherichia coli K-12 To be used as a nutrient in animal food. All animals 8/17/2017 FDA has no questions. (PDF - 4 pages)
25 G-Science, Inc. Clinoptilolite To be used as an anticaking agent at levels up to 2% by weight in the complete diet. Cattle, swine, goats, sheep, poultry, cats, and dogs. 8/21/2017 At notifier’s request, FDA ceased to evaluate the notice. (PDF - 1 page)
26 KnipBio, Inc. Methylobacterium extorquens protein To be used as a source of protein to replace soybean or fish meal in food for aquaculture species at a level up to 10% of the diet. Aquaculture species. 2/7/2018 Pending
27 Agrivida, Inc. Ground grain obtained from a corn (Zea mays) variety that expresses an altered appA 6-phytase gene obtained from Escherichia coli strain K12 To increase the digestibility of phytin-bound phosphorous or to increase phosphorous availability from phytate in swine feeds when used to provide 500-4500 phytase activity units (FTU)/kg complete feed. Swine 9/6/2018 Pending
28 CJ CheilJedang Corporation L-Threonine Fermentation Product (75%) produced by a bioengineered Corynebacterium glutamicum To be used as a source of the nutrient L-threonine in the diets of livestock and poultry. Livestock and poultry. 11/6/2018 Pending

 

Page Last Updated: 11/13/2018
Note: If you need help accessing information in different file formats, see Instructions for Downloading Viewers and Players.
Language Assistance Available: Español | 繁體中文 | Tiếng Việt | 한국어 | Tagalog | Русский | العربية | Kreyòl Ayisyen | Français | Polski | Português | Italiano | Deutsch | 日本語 | فارسی | English