Webcast | Virtual
Event Title
Eco-NAMs Webinar Series | In Silico Approaches to Replace Acute Fish Toxicity
May 28, 2026
- Date:
- May 28, 2026
- Time:
- 8:00 a.m. - 9:00 a.m. ET
The Eco-NAMS webinar series is co-organized by the U.S. Food and Drug Administration, U.S. Environmental Protection Agency, European Medicines Agency, Health and Environmental Sciences Institute, National Institute for Environmental Studies (Japan), and PETA Science Consortium International e.V.
The series aims to offer the most informative and up-to-date science on the use of new approach methodologies (NAMs) for ecotoxicity assessments (Eco-NAMs) and provides an open forum for scientists from academia, industry, non-government organizations, regulatory authorities, and other interested parties including the general public to learn about and discuss various ecotoxicity NAMs topics.
The series' third webinar, In silico approaches to replace acute fish toxicity, will feature presentations by Anna Lombardo, researcher at Istituto di Ricerche Farmacologiche “Mario Negri” and Paul Thomas, President, Model Developer and Expert Ecotoxicologist at KREATiS.
Ms. Lombardo will present a brief introduction to Quantitative Structure Activity Relationships (QSARs) and read-across methods, and then discuss the use of the VEGA (Virtual models for property Evaluation of chemicals within a Global Architecture) HUB tools to assess fish acute toxicity. Through case studies focused on fish acute toxicity that can also be applicable to other endpoints, she will explain the read-across approach used in VERA, the QSAR models available in VEGA, and JANUS, which is a tool for screening and prioritization.
Dr. Thomas will discuss the use of mechanistic QSARs for acute fish toxicity prediction, providing background information on the published structural alert scheme, mechanism of action (MechoA), addressing frequently asked questions. His presentation will demonstrate how the method can link toxic effects between different species and acute and chronic exposure using a robust mechanistic approach.
Disclaimer: The views expressed in this webinar series are those of the presenters and do not necessarily represent the official views or policies of the US government, the EMA and the NIES. The US FDA, US EPA, EMA and NIES involvement in this webinar series does not imply official endorsement of, or responsibility for, the opinions, ideas, data, products, or services presented.