• Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

Drugs

  • Print
  • Share
  • E-mail

Spectrum of Diseases/Conditions

 

 Spectrum of Diseases by Therapeutic Area found in 

Written Requests as of March 31, 2014

 

 Contents:


 

 Addiction  

  • Maintenance of abstinence from alcohol in patients with alcohol dependency
  • Neonatal abstinence syndrome (NAS)
  • Smoking cessation

 Analgesia/Anesthesiology/Anti-inflammatory        

  • Anesthesia
  • Anxiolysis
  • Fever reduction
  • Pain
    • Chronic
    • Malignancy-related breakthrough pain
    • Mild
    • Moderate
    • Post-operative
    • Severe
  • Sedation
    • Initially intubated & mechanically ventilated pediatric subjects in an intensive care setting
  • Skeletal muscle relaxation to facilitate rapid sequence and routine endotracheal intubation

 Cardiovascular Disease      

  • Acute coronary disease 
  • Congenital heart disease  
  • Congestive heart failure
  • Hypertension
    • General
    • Post-operative hypertension
  • Pulmonary hypertension
    • Primary/secondary
    • Post-surgical
  • Raynaud's Phenomenon
  • Tachyarrhythmia

 Dermatology        

  • Alopecia areata
  • Aphthous ulcer
  • Candidiasis (cutaneous, oropharyngeal) 
  • Dermatosis (steroid-responsive dermatosis)
  • Dermatitis (atopic dermatitis)
  • Ichthyosis vulgaris
  • Idiopathic urticaria (chronic)
  • Mild to moderate plaque psoriasis 
  • Molluscum contagiosum
  • Oral mucositis
  • Pediculosis humanis capitis (head lice and their ova)
  • Severe recalcitrant nodular acne
  • Skin and skin structure infections
  • Tinea
    • Capitis
    • Cruris
    • Pedis

 Endocrinology/Metabolism/Bone        

  • Acromegalic gigantism
  • Bone mineral density (BMD)
    • BMD in anorexia nervosa patients
    • BMD in osteogenesis imperfecta patients
    • BMD in postmenarcheal adolescents with secondary amenorrhea
  • Delayed puberty in boys with primary and secondary hypogonadism
  • Diabetes Mellitus
    • Type 1
    • Type 2
  • Failure to thrive in pediatric AIDS patients
  • Growth-hormone-secreting lesions of the pituitary gland
  • Gynecomastia
  • Hypercholesterolemia (heterozygous familial hypercholesterolemia)
  • Hyperparathyroidism (renal failure secondary to hyperparathyroidism)
  • Hypocalcemia management in patients on hemodialysis
  • McCune-Albright Syndrome
  • Obesity
    • General
    • Hypothalamic
  • Osteogenesis Imperfecta (OI)
  • Tetrahydrobiopterin- (BH4-) responsive phenylketonuria (PKU)
  • Testotoxicosis

 Gastroenterology        

  • Antiemesis
    • Treatment and prevention of nausea and vomiting associated with emetogenic chemotherapy
    • Prevention of post-operative nausea and vomiting
  • Constipation (general )
  • Crohn's Disease
  • Diarrhea (acute)
  • Erosive Esophagitis 
  • Gastroesophageal Reflux Disease (GERD)
  • Irritable Bowel Syndrome (IBS)
  • Nephropathic cystinosis 
  • Ulcerative Colitis (UC)
  • Ulcers

 Hematology/Coagulation        

  • Deep vein thrombosis (DVT)
  • Iron deficiency in patients undergoing chronic hemodialysis
  • Sickle cell disease
  • Thrombocythemia
  • Thrombocytopenia
  • Thromboembolism

 Immunomodulators        

  • Immune suppression
  • Prevention of organ rejection following renal transplantation

 Infectious Disease (viral)        

  • Cytomegalovirus (CMV)
  • Hepatitis B virus (HBV)
    • Chronic 
  • Hepatitis C virus (HCV)
    • Chronic
  • Herpes simplex virus (HSV)
  • Human Immunodeficiency Virus (HIV) infection New!
       
    • prophylaxis of HIV infection in exposed neonates
    • perinatal transmission of HIV infection
  • Influenza A/B
  • Perinatal transmission of HIV infection
  • Symptoms associated with common cold and influenza
  • Varicella zoster virus (VZV)

 Infectious Disease (non viral)        

  • Acute pyelonephritis New!
  • Aspergillosis (invasive)
  • Candidiasis
  • Cerebrospinal fluid (CSF) shunt infection
  • Community-acquired pneumonia (CAP)
  • Complicated intra-abdominal infections (cIAI)
  • Complicated UTI
    • Acute pyelonephritis
  • Fungal infection (invasive)
    • Associated fever and neutropenia
  • Helicobacter pylori infection (H. pylori)
  • Malaria
  • Meningitis (bacterial)
  • Mold infections (rare mold)
  • Otitis media (OM)(recurrent)/OM treatment failures
  • Pneumonia (bacteremic)
  • Resistant infection or infections unresponsive to the first choice antibiotic
  • Skin and skin structure infections
  • Tuberculosis

 Medical Imaging        

  • Cardiac imaging
  • Lesions in the central nervous system, body, extracranial/extraspinal tissues
  • Myocardial perfusion imaging

  Neurology        

  • Insomnia in patients with ADHD
  • Intractable seizures associated with Dravet syndrome 
  • Migraine
  • Multiple sclerosis (MS)
    • Relapsing forms of MS 
  • Narcolepsy
    • Cataplexy in narcolepsy New!
  • Seizures
    • Generalized
    • Lennox-Gastaut Sundrome (LGS) New!
    • Partial
  • Spasticity management
  • Obstructive sleep apnea (OSA) (excessive sleepiness in OSA)
  • Tourette’s syndrome
    • ADHD in patients with Tourette's disorder

 Oncology        

  • Allogeneic bone marrow transplants
  • Antineoplasia
  • Brain tumors and other solid tumors
  • Chemotherapy toxicity protection
  • CNS malignancies and solid tumors
  • Giant cell tumor of bone and osteosarcoma 
  • Hematologic tumors
    • CNS lymphomas
    • Leukemia
      • Acute lymphoblastic leukemia
      • Acute myelogenous leukemia
      • CNS leukemia
      • Mixed linear acute leukemia
      • Philadelphia positive (Ph+) chronic myelogenous leukemia
    • Hodgkin's lymphoma
    • Non-Hodgkin's lymphoma
      • Anaplastic large cell lymphoma 
  • Hematopoietic stem cell mobilization in patients with pediatric malignancies eligible for autologous stem cell transplantation
  • Myelodysplastic syndromes 
  • Neuroblastoma
  • Pediatric malignancies
  • Refractory/relapse malignancies

 Ophthalmology        

  • Conjunctivitis
    • Allergic
    • Bacterial
    • Neonatal
  • Intraocular pressure
  • Post-operative inflammation following cataract surgery
  • Uveitis   

Psychiatry

  • Adolescent schizophrenia
  • Attention deficit hyperactivity disorder (ADHD)
  • Autism and Autism Spectrum Disorder 
    • Core social impairment symptoms 
  • Bipolar disorder (mania associated with bipolar disorder)
  • Depression/Major Depressive Disorder (MDD)
  • General Anxiety Disorder (GAD)
  • Obsessive compulsive disorder (OCD)
  • Panic disorder

 Pulmonary        

  • Allergic Rhinitis
  • Asthma
  • Bronchopulmonary dysplasia
  • Bronchospasm (treatment and prevention)
    • Prevention of bronchospasm in patients with obstructive airway disease

 Renal Disease

  • Anemia due to chronic kidney disease (CKD) 
  • End stage renal disease
  • Hyponatremia 

Rheumatology

  • Familial Mediterranean Fever (FMF)
  • Juvenile Idiopathic Arthritis (JIA)/Juvenile Rheumatoid Arthritis (JRA)
    • Polyarticular Juvenile Idiopathic Arthritis (PJIA) 
  • Management of fibromyalgia

Urologic

  • Detrusor Hyperreflexia
  • Detrusor overactivity in neurological condition