NCTR Research Highlights
Current Highlight from January 23, 2015
Human Respiratory Coronaviruses Detected in Patients with Influenza-Like Illness in Arkansas
Scientists from FDA's NCTR and Center for Biologics Evaluation and Research, CDC, The Ohio State University, University of Arkansas for Medical Sciences, and the Arkansas Department of Health, investigated the molecular epidemiology of human coronavirus (HCoV) strains circulating during the 2009/2010 influenza season, their genetic variability, and their association with reported influenza symptoms. The study analyzed 200 clinical nasal-swab samples and showed that 39.5% of the non-influenza respiratory illnesses were caused by HCoVs, with HCoV-OC43 and NL63-like being the most frequently detected strains. Additionally, a possible new strain of CoV (similar to feline CoV) was detected in samples from three patients. Some strains of coronavirus induce symptoms similar to influenza causing individuals to seek treatment. Recently, more serious forms of coronavirus have surfaced (MERS and SARS) causing deaths in more serious infections. This study is available online at Virology & Mycology.
For additional information, please contact Marli Azevedo, Ph.D., Division of Microbiology, FDA/NCTR.
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