U.S. flag An official website of the United States government
  1. Home
  2. Tobacco Products
  3. Tobacco Science & Research
  4. Research
  5. ITO Chemical Analysis of Mainstream Smoke from Little Cigars, Cigarillos and Large Cigars to Determine Quantities of Carbonyls
  1. Tobacco Science & Research

ITO Chemical Analysis of Mainstream Smoke from Little Cigars, Cigarillos and Large Cigars to Determine Quantities of Carbonyls

ITO Chemical Analysis of Mainstream Smoke from Little Cigars, Cigarillos and Large Cigars to Determine Quantities of Carbonyls

Principal Investigator: Andrew Mooney and Todd Cecil

Funding Mechanism: Research Contract

ID number:  HHSF223201310037I7T

Award Date: 8/2/2016

Institution: Labstat International


Carbonyls (including acetaldehyde, acrolein, 2-butanone, crotonaldehyde, and formaldehyde) are strong, toxic irritants of the skin, eyes and nasal passage. Human exposure to these chemical constituents is introduced through tobacco smoke. The goal of this project is to conduct chemical analyses on little cigars, cigarillos, and large cigars to determine mainstream smoke quantities of acrolein (the main contributor to non-cancer respiratory effects from cigarette smoke) and other carbonyls (all of which have shown to cause cancer). Investigators will measure carbonyl quantities in a variety of little cigar (10), cigarillo (10) and large cigar (5) tobacco products currently marketed in the United States, under ISO and Canadian intense smoking regimens and using CORESTA recommended methods for carbonyl analysis.