Exploring Cardiovascular and Other Health Associations of Electronic Cigarette Use in US Persons of Hispanic Heritage: The Hispanic Community Health Study / Study of Latinos (HCHS/SOL)
Principal Investigator(s): Thanh Huyen Thiv Vu
Funding Mechanism: NIH Grant
ID number: 1R03HL144902-01
Award Date: 9/13/2018
Institution: Northwestern University at Chicago
Information on the effects of electronic nicotine delivery system (ENDS) use on cardiovascular disease (CVD) and other health risks in minority populations would be useful. The goal of this study is to examine associations between ENDS use and CVD and other health risks in the Hispanic/Latino population. Researchers will analyze existing data from a large community-based sample of more than 12,000 individuals of Hispanic/Latino origin (ages 18-74 at baseline) who participated in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) at both baseline (2008-2011) and follow-up (2015-2017). Study aims are: (1) to determine the prevalence of ENDS use and assess demographic, socio-economic, and cultural factors associated with use; (2) to study associations of ENDS use with levels of CVD risk factors, other health measures, assessments of subclinical atherosclerosis, and markers of inflammation, including heart rate, blood pressure, high-density lipoproteins (HDL), low-density lipoproteins (LDL), triglycerides, fasting glucose, body mass index, and white blood count, taking into account history and current use of tobacco products; (3) to study changes between baseline and follow-up in associations of ENDS use with CVD risk factors, other health measures, and markers of inflammation, taking into account history and current use of tobacco products; and (4) to obtain new data to examine ENDS use as it relates to motivations, dose, flavors, and duration by mailing a questionnaire to users who participated in the HCHS/SOL follow-up. Findings will provide new information about the cardiovascular impact of ENDS use in the Hispanic/Latino population.