Principal Investigator: Cliff Watson / Matt Walters
Funding Mechanism: Interagency Agreement
ID number: 224-10-9022
Award Date: 4/1/2011
Institution: Centers for Disease Control and Prevention
The chemical composition and product design features of cigarettes are extremely diverse. In this project, investigators will analyze the 50 top-selling cigarette brands for select harmful and potentially harmful constituents (HPHCs), product design and composition. HPHCs will be analyzed under both International Organization of Standardization (ISO) and Canadian Intense (CI) smoking regimens. Smoke yields and tobacco filler will be quantified using various analytical methods including ion chromatography (IC), liquid chromatography/mass spectrometry (LC/MS), and gas chromatography/mass spectrometry (GC/MS). This information will inform FDA about the current cigarette marketplace and may be useful for FDA during product application reviews.