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Comparative Brand Analysis (FDA 50)

Principal Investigator: Cliff Watson / Matt Walters

Funding Mechanism: Interagency Agreement

ID number: 224-10-9022

Award Date: 4/1/2011

Institution: Centers for Disease Control and Prevention

The chemical composition and product design features of cigarettes are extremely diverse. In this project, investigators will analyze the 50 top-selling cigarette brands for select harmful and potentially harmful constituents (HPHCs), product design and composition. HPHCs will be analyzed under both International Organization of Standardization (ISO) and Canadian Intense (CI) smoking regimens. Smoke yields and tobacco filler will be quantified using various analytical methods including ion chromatography (IC), liquid chromatography/mass spectrometry (LC/MS), and gas chromatography/mass spectrometry (GC/MS). This information will inform FDA about the current cigarette marketplace and may be useful for FDA during product application reviews.