The FDA Office of Women’s Health (OWH) awards research grants for 1-2 year studies to support FDA regulatory decision-making and advance the science of women’s health. OWH has funded research projects that address health issues affecting women across their lifespan. This page highlights OWH-funded research related to autoimmune disease.
Clinical and Biological Significance of Three Identified Targets in Systemic Lupus Erythematosus Patient PBMCs: IL-18, TNFSF13B, and FOXP3 - Beverly Lyn-Cook, PhD, NCTR (13)
Use of innate immune response modulators in women: The perfect storm to trigger autoimmune disease?
- Daniela Verthelyi, MD, PhD, CDER (13)
Sex Disparities in Autoimmune Treatment Response - Lanyan Fang, PhD, CDER (12)
A Mechanistic Study of the Capacity of Silicone to Present (Self) Antigens to the Immune System - Jack Ragheb, PhD, CDER (12)
Lupus Workshop – Shashi Amur, Special funding/CDER (11)
Sex and ethnic differences in expression of Toll-like receptors (TLR-3, TLR-7, and TLR-9) in systemic lupus erythematous (SLE): new targets for emerging therapeutics – Beverly Lyn-Cook, PhD, NCTR (11)
The Role of Vaccine Adjuvant Mediated TACI Upregulation in SLE - Mustafa Akkoyunlu, PhD, CBER (08)
Gender, Ethnicity and Pharmacogenomics in Systemic Lupus Erythematosus (SLE) - Shashi Amur, PhD, CDER (07)
Sex differences in Systemic Lupus Erythematosus (SLE): Effects of a single nucleotide polymorphism (SNP) in the prolactin (PRL) gene on individual response to prasterone therapy - Neera Gopee, PhD, NCTR (07)
Evaluation of the Tk knockout (TkKO) mouse as a model of systemic lupus erythematosus - Vasily Dobrovolsky, PhD, NCTR (00)
Postmarketing drug risk assessment using the ARAMIS database in RA patients – Mary Willy, PhD, CDER (99)
A novel approach to the treatment of lupus nephritis - Dennis Klinman, MD, PhD, CBER (96)
Cytokine induced activation of the Jak kinase/STAT transcription factor pathway in immune cells (monocytes and lymphocytes) of patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) - David S. Finbloom, MD, CBER (95)
Hormonal regulation of cytokine producing cells in women with systemic lupus erythematosus - Dennis Klinman, MD, PhD, CBER (95)