The invention offered for license is in the field of veterinary medicine. Specifically, it relates to a novel, serum-free medium used to isolate and expand MSCs.
MSCs are a potentially effective therapy for treating a variety of conditions in veterinary medicine. They are isolated and expanded in vitro in a medium that is supplemented with fetal bovine serum (FBS). However, the use of FBS as a medium component during manufacturing may pose several problems. FBS can be a source of unwanted pathogens. The serum can introduce carry-over components that may elicit an immune response. Further, lot-to-lot variations in FBS quality may introduce inconsistencies between batches of MSCs.
This invention uses a novel FBS-free medium that supports both the isolation and expansion of MSCs from canine adipose tissue while removing the unwanted pathogens, immune response and lot-to-lot variations.
|Potential Commercial Applications||Competitive Advantages|
Lax Devireddy, Michael Myers, Rudell Screven
FDA Reference Number: E-2017-010
Charlene Maddox, Ph.D.
FDA Technology Transfer Program
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