This technology describes a low passage Edmonston strain of measles virus that is more sensitive to neutralization by serum antibodies than the same virus that has been passaged more. This strain can be used to detect lower levels of measles neutralizing antibody than other measles virus strains. This material could also be used to assess effectiveness of anti-measles therapeutics or vaccines.
Potential Commercial Applications:
Research Tool -- patent protection is not being pursued for this technology
P Albrect et al. Role of virus strain in conventional and enhanced measles plaque neutralization test. J Virol Methods. 1981 Dec;3(5):251-260. PubMed abs
Bill Ronnenberg, JD-MIP, MS
FDA Technology Transfer Program
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OTT Reference No: E-125-2007/0
Updated: August 9, 2015