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FDA Grand Rounds

The FDA Grand Rounds is an educational presentation that is webcast monthly to highlight cutting-edge research underway across the Agency and its impact on protecting and advancing public health. Each session features an FDA scientist presenting on a key public health challenge and how FDA is applying science to its regulatory activities. The 45-minute educational presentation is followed by questions from the audience. You can also view the presentation under Past Grand Rounds following the live webcast. #FDAGrandRounds.

Upcoming Event

A Modular Approach for Enhanced Plasmid Subtyping and AMR Gene Profiling of Plasmids

Thursday, February 9, 2023
12:00 p.m. - 1:00 p.m. EST

About the Presentation

Plasmids are a major factor in the spread of antimicrobial resistance genes.  Current plasmid typing methods do not account for the great degree of genetic diversity associated with the recombination mechanisms that allow plasmids to acquire antimicrobial resistance genes.  In this presentation we introduce an enhanced plasmid subtyping method that not only identifies the genetic elements exclusive to and indicative of a plasmid type, but also characterizes plasmids based on the DNA sequence and relative position of these genetic elements as they are rearranged through plasmid recombination mechanisms.

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