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  1. HIV (Human Immunodeficiency Virus)

Antiretroviral drugs used in the treatment of HIV infection

Drugs Used in the Treatment of HIV Infection

FDA-approved medicines used in the treatment of HIV can be found at Drugs@FDA or DailyMed. This list may not be comprehensive and it was last updated on April 12, 2018.

Multi-class Combination Products

 BrandGeneric NamePediatric UseApproval DateTime to Approval
 Atripla efavirenz, emtricitabine and tenofovir disoproxil fumarateSee label 12-July-06 2.5 months
 Complera emtricitabine, rilpivirine, and tenofovir disoproxil fumarateSee label 10-August-11 6 months
 Evotaz atazanavir sulfate, cobicistatSee label 29-January-15 9 months
 Prezcobix cobicistat, darunavir ethanolateSee label 29-January-15 10months
 Stribild elvitegravir, cobicistat, emtricitabine, tenofovir disoproxil fumarateSee label 27-August-12 6 months

Nucleoside Reverse Transcriptase Inhibitors (NRTIs);

FDA-approved medicines used in the treatment of HIV can be found at Drugs@FDA or DailyMed.

Brand NameGeneric NamePediatric UseApproval DateTime to Approval
 Combivir lamivudine and zidovudineSee label 27-Sep-97 3.9 months
 Emtriva emtricitabine, FTCSee label 02-Jul-03 10 months
 Epivir lamivudine, 3TCSee label 17-Nov-95 4.4 months
 Epzicom abacavir and lamivudineSee label 02-Aug-04 10 months
 Hivid zalcitabine, dideoxycytidine, ddC (no longer marketed)See label 19-Jun-92 7.6 months
 Retrovir zidovudine, azidothymidine, AZT, ZDVSee label 19-Mar-87 3.5 months
 Trizivir abacavir, zidovudine, and lamivudineSee label 14-Nov-00 10.9 months
 Truvada tenofovir disoproxil fumarate and emtricitabineSee label 02-Aug-04 5 months
 Videx EC enteric coated didanosine, ddI ECSee label 31-Oct-00 9 months
 Videx didanosine, dideoxyinosine, ddISee label 9-Oct-91 6 months
 Viread tenofovir disoproxil fumarate, TDFSee label 26-Oct-01 5.9 months
 Zerit stavudine, d4TSee label 24-Jun-94 5.9 months
 Ziagen abacavir sulfate, ABCSee label 17-Dec-98 5.8 months

 Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs)

FDA-approved medicines used in the treatment of HIV can be found at Drugs@FDA or DailyMed.

 Brand NameGeneric NamePediatric UseApproval DateTime to Approval
 Edurant rilpivirineSee label 20-May-11 10 months
 Intelence etravirineSee label 18-Jan-08 6 months
 Rescriptor delavirdine, DLVSee label 4-Apr-97 8.7 months
 Sustiva efavirenz, EFVSee label 17-Sep-98 3.2 months
 Viramune(Immediate Release) nevirapine, NVPSee label 21-Jun-96 3.9 months
 Viramune XR (Extended Release) nevirapine, NVP  25-Mar-11 9.9 months

Protease Inhibitors (PIs) 

FDA-approved medicines used in the treatment of HIV can be found at Drugs@FDA or DailyMed.

 Brand NameGeneric NamePediatric UseApproval DateTime to Approval
 Agenerase amprenavir, APV (no longer marketed)See label15-Apr-99 6 months
 Aptivus tipranavir, TPVSee label 22-Jun-05 6 months
 Crixivan indinavir, IDV,See label 13-Mar-96 1.4 months
 Fortovase saquinavir (no longer marketed)See label 7-Nov-97 5.9 months
 Invirase saquinavir mesylate, SQVSee label 6-Dec-95 3.2 months
 Kaletra lopinavir and ritonavir, LPV/RTVSee label 15-Sep-00 3.5 months
 Lexiva Fosamprenavir Calcium, FOS-APVSee label 20-Oct-03 10 months
 Norvir ritonavir, RTVSee label 1-Mar-96 2.3 months
 Prezista darunavirSee label 23-Jun-06 6 months
 Reyataz atazanavir sulfate, ATVSee label 20-Jun-03 6 months
 Viracept nelfinavir mesylate, NFVSee label 14-Mar-97 2.6 months

Fusion Inhibitors

FDA-approved medicines used in the treatment of HIV can be found at Drugs@FDA or DailyMed.

 Brand NameGeneric NamePediatric Use Approval Date Time to Approval
 Fuzeon enfuvirtide, T-20See label 13-Mar-03 6 months

 Entry Inhibitors - CCR5 co-receptor antagonist

FDA-approved medicines used in the treatment of HIV can be found at Drugs@FDA or DailyMed.

 Brand NameGeneric NamePediatric UseApproval DateTime to Approval
 Selzentry maravirocSee label 06-August-07 8 months

 HIV integrase strand transfer inhibitors

FDA-approved medicines used in the treatment of HIV can be found at Drugs@FDA or DailyMed.

 Brand NameGeneric NamePediatric UseApproval DateTime to Approval
Isentress raltegravirSee label 12--Oct-07 6 months
Tivicay  dolutegravirSee label 13-August-13 6 months
VitektaelvitegravirSee label24-September-1424 months

Approved and Tentatively Approved Antiretrovirals in Association with the President's Emergency Plan (PEPFAR)