Antiretroviral drugs used in the treatment of HIV infection
Drugs Used in the Treatment of HIV Infection
FDA-approved medicines used in the treatment of HIV can be found at Drugs@FDA or DailyMed. This list may not be comprehensive and it was last updated on April 12, 2018.
Multi-class Combination Products
| Brand | Generic Name | Pediatric Use | Approval Date | Time to Approval |
|---|---|---|---|---|
| Atripla | efavirenz, emtricitabine and tenofovir disoproxil fumarate | See label | 12-July-06 | 2.5 months |
| Complera | emtricitabine, rilpivirine, and tenofovir disoproxil fumarate | See label | 10-August-11 | 6 months |
| Evotaz | atazanavir sulfate, cobicistat | See label | 29-January-15 | 9 months |
| Prezcobix | cobicistat, darunavir ethanolate | See label | 29-January-15 | 10months |
| Stribild | elvitegravir, cobicistat, emtricitabine, tenofovir disoproxil fumarate | See label | 27-August-12 | 6 months |
Nucleoside Reverse Transcriptase Inhibitors (NRTIs);
FDA-approved medicines used in the treatment of HIV can be found at Drugs@FDA or DailyMed.
| Brand Name | Generic Name | Pediatric Use | Approval Date | Time to Approval |
|---|---|---|---|---|
| Combivir | lamivudine and zidovudine | See label | 27-Sep-97 | 3.9 months |
| Emtriva | emtricitabine, FTC | See label | 02-Jul-03 | 10 months |
| Epivir | lamivudine, 3TC | See label | 17-Nov-95 | 4.4 months |
| Epzicom | abacavir and lamivudine | See label | 02-Aug-04 | 10 months |
| Hivid | zalcitabine, dideoxycytidine, ddC (no longer marketed) | See label | 19-Jun-92 | 7.6 months |
| Retrovir | zidovudine, azidothymidine, AZT, ZDV | See label | 19-Mar-87 | 3.5 months |
| Trizivir | abacavir, zidovudine, and lamivudine | See label | 14-Nov-00 | 10.9 months |
| Truvada | tenofovir disoproxil fumarate and emtricitabine | See label | 02-Aug-04 | 5 months |
| Videx EC | enteric coated didanosine, ddI EC | See label | 31-Oct-00 | 9 months |
| Videx | didanosine, dideoxyinosine, ddI | See label | 9-Oct-91 | 6 months |
| Viread | tenofovir disoproxil fumarate, TDF | See label | 26-Oct-01 | 5.9 months |
| Zerit | stavudine, d4T | See label | 24-Jun-94 | 5.9 months |
| Ziagen | abacavir sulfate, ABC | See label | 17-Dec-98 | 5.8 months |
Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs)
FDA-approved medicines used in the treatment of HIV can be found at Drugs@FDA or DailyMed.
| Brand Name | Generic Name | Pediatric Use | Approval Date | Time to Approval |
|---|---|---|---|---|
| Edurant | rilpivirine | See label | 20-May-11 | 10 months |
| Intelence | etravirine | See label | 18-Jan-08 | 6 months |
| Rescriptor | delavirdine, DLV | See label | 4-Apr-97 | 8.7 months |
| Sustiva | efavirenz, EFV | See label | 17-Sep-98 | 3.2 months |
| Viramune(Immediate Release) | nevirapine, NVP | See label | 21-Jun-96 | 3.9 months |
| Viramune XR (Extended Release) | nevirapine, NVP | 25-Mar-11 | 9.9 months |
Protease Inhibitors (PIs)
FDA-approved medicines used in the treatment of HIV can be found at Drugs@FDA or DailyMed.
| Brand Name | Generic Name | Pediatric Use | Approval Date | Time to Approval |
|---|---|---|---|---|
| Agenerase | amprenavir, APV (no longer marketed) | See label | 15-Apr-99 | 6 months |
| Aptivus | tipranavir, TPV | See label | 22-Jun-05 | 6 months |
| Crixivan | indinavir, IDV, | See label | 13-Mar-96 | 1.4 months |
| Fortovase | saquinavir (no longer marketed) | See label | 7-Nov-97 | 5.9 months |
| Invirase | saquinavir mesylate, SQV | See label | 6-Dec-95 | 3.2 months |
| Kaletra | lopinavir and ritonavir, LPV/RTV | See label | 15-Sep-00 | 3.5 months |
| Lexiva | Fosamprenavir Calcium, FOS-APV | See label | 20-Oct-03 | 10 months |
| Norvir | ritonavir, RTV | See label | 1-Mar-96 | 2.3 months |
| Prezista | darunavir | See label | 23-Jun-06 | 6 months |
| Reyataz | atazanavir sulfate, ATV | See label | 20-Jun-03 | 6 months |
| Viracept | nelfinavir mesylate, NFV | See label | 14-Mar-97 | 2.6 months |
Fusion Inhibitors
FDA-approved medicines used in the treatment of HIV can be found at Drugs@FDA or DailyMed.
| Brand Name | Generic Name | Pediatric Use | Approval Date | Time to Approval |
|---|---|---|---|---|
| Fuzeon | enfuvirtide, T-20 | See label | 13-Mar-03 | 6 months |
Entry Inhibitors - CCR5 co-receptor antagonist
FDA-approved medicines used in the treatment of HIV can be found at Drugs@FDA or DailyMed.
| Brand Name | Generic Name | Pediatric Use | Approval Date | Time to Approval |
|---|---|---|---|---|
| Selzentry | maraviroc | See label | 06-August-07 | 8 months |
HIV integrase strand transfer inhibitors
FDA-approved medicines used in the treatment of HIV can be found at Drugs@FDA or DailyMed.