Arthritis Advisory Committee Meeting

June 2, 3, 2004

Issues: Acute and Chronic Gout



1.     Braden GL, Warzynski MJ, Golightly M, Ballow M. Cell-Mediated Immunity in

Allopurinol-Induced Hypersensitivity. Clin Immun & Immunopath. 1994;70:145-151.

2.     Choi HK, Atkinson K, Karlson EW, Willett W, Curhan G. Alcohol intake

and risk of incident gout in men: a prospective study. Lancet. 2004;363:1277-81.

3. Choi HK, Atkinson K, Karlson EW, Willett W, Curhan G. Purine-rich foods, dairy and protein intake, and the risk of gout in men. N Engl J Med. 2004;350:1093-103.

4.  Darmawan J, Rasker JJ, Nuralim H. The Effect of Control and Self-Medication of Chronic Gout in a Developing Country. Outcome After 10 Years. J  Rheumatol 2003;30:2437-43.

5.  Emmerson BT, Hazelton RA, Frazer IH. Some Adverse Reactions to Allopurinol may be Mediated by Lymphocyte Reactivity to Oxypurinol. Arthritis Rheum. 1988;31:436-440.

6.  Fam AG, Dunne SM, Iazzetta J, Paton TW. Efficacy and Safety of Desensitization to Allopurinol following Cutaneous Reactions. Arthritis & Rheumatism. 2001;44:231-238.

7. Hamanaka H, Mizutani H, Nouchi N, Shimizu Y, Shimizu M. Allopurinol hypersensitivity syndrome: hypersensitivity to oxypurinol but not allopurinol. Clin & Exp Derm 1998;23:32-34.

8.  Lockard O, Harmon C, Nolph K, Irvin W. Allergic Reaction to Allopurinol with Cross-Reactivity to Oxypurinol. Ann Intern Med. 1976;85:333-335.

9. Naisbitt DJ, Pirmohamed M, Park BK. Immunopharmacology of Hypersensitivity Reactions to Drugs. Current Allergy and Asthma Reports. 2003;3:22-29.

10. Pascual E, Pedraz T. Gout. Current opinion in Rheumatology. 2004;16:282-286.

11.Pichler, WJ. Delayed Drug Hypersensitivity Reactions. Ann Intern Med. 


12.Pluim HJ, van Deuren M, Wetzels JFM. The allopurinol hypersensitivity

     syndrome. Netherlands Journal of Medicine. 1998;52:107-110.

13.Rott KT, Agudelo CA. Gout. JAMA. 2003;289:2857-60.

14.Terkeltaub RA. Clinical practice. Gout. N Engl J Med. 2003;349:1647-55.

15.Wortman RL. Gout and hyperuricemia. Current Opinion in Rheumatology.

     2002; 14:281-286.