In this research program, we evaluate the impact of emerging display technologies on medical image visualization and develop quantitative bench testing methods for assessing the color performance of medical imaging devices. Our goal is to assist in streamlining the FDA’s review of medical devices, using regulatory science to lessen the need for sponsors to engage in expensive clinical trials. Our current focus is on developing device characterization methods for surgical pathology whole-slide imaging, flexible and capsule endoscopy, dermatology with mobile applications and multi-spectral imaging, and retinal photography in ophthalmoscopy.
Current external funding sources
Wei-Chung Cheng, Ph.D.
Aldo Badano, Ph.D.
Spectroradiometer, Photo Research PR-730
Spectroradiometer, Konica-Minolta CS-2000
Illuminance spectrophotometer, Konica-Minolta CL-500A
Image photometer, Photometrica P199F
DICOM calibrated, wide color gamut, OLED, stereo (lenticular, shutter-based, head-mounted), large-sized, projection, mobile, transflective, CRT
DVI/HDMI FPGA development boards
Video signal generator
Color calibration kits
Illumination-controlled observation room
Eyetracker, SR EyeLink 1000
FM-100 Color Discrimination Test
Reflective color targets (Munsell, X-Rite, Pantone, LabSphere)
Reflective spectrophotometer (X-Rite iOne Pro, RM200 Capsure)
Tunable light source, Gooch and Housego OL490
Tunable color filter, CRi VariSpec
Microscopes with motorized XYZ stage
H&E stained tissue slides
GivenImaging PillCam SB3
Ophthalmoscope, Welch Panoptic
Eye models (Reti Eye, Ocular Instruments)
Pantone SkinTone targets
Medical photography (close-up lens and ring-light)
Public domain software
Relevant standards & guidances
Standards and professional guidances
- IEC 62563-1: Medical image display systems – Part 1: Evaluation methods (Dr. Badano is the current convenor of Maintenance Team 51 of IEC Technical Committee 62B)
- AAPM Working Group on Medical Displays (WGMD)
- AAPM Task Group No. 196, Requirements and methods for color displays in medicine
- AAPM Task Group No. 260, Considerations for the Use of Handheld Devices for Viewing Medical Images
- NEMA DICOM WG-13, Visible Light
Selected peer-review publications
- Wang et al.,Comparison of methods for quantitative evaluation of endoscopic distortion, In SPIE Medical Imaging, 2015.
- Gallas et al., Evaluation environment for digital and analog pathology: a platform for validation studies, Journal of Medical Imaging, 2014.
- Badano et al., Consistency and standardization of color in medical imaging: a consensus report, Journal of digital imaging, 2014.
- Choi et al., Effect of Veiling Glare on Detectability in High-Dynamic-Range Medical Images, Journal of Display Technology, 2014.
- Yamazaki et al., Spatial resolution and noise in organic light-emitting diode displays for medical imaging applications, Optics Express, 2013.
- Yamazaki et al., Image Quality Characteristics of Handheld Display Devices for Medical Imaging, PloS, 2013.
- Wu et al., 30.3: Comparison of On-Screen Display-based and ICC Profile-based Calibration for OLED Displays, In SID Symposium Digest of Technical Papers, 2013
- Cheng et al., Assessing color reproducibility of whole-slide imaging scanners, In SPIE Medical Imaging, 2013.
- Cheng et al., Impact of solid-state lighting on observer performance of color discrimination, In SPIE Medical Imaging, 2012.