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  1. Orphan Products Natural History Grants

Find Funding Opportunities for Natural History Studies

Upcoming Receipt Dates:
Our current receipt date has closed.  Please check back early 2020 for updates on the next RFA.  You can also subscribe for automatic notifications on grants.gov


Recent Receipt Dates that have Closed: 

Natural History Studies Addressing Unmet Needs of Rare Diseases: Orphan Products Research Project Grant (R01)


Receipt Date: January 10, 2019

FOA Number: RFA-FD-19-001


Funding Opportunity Purpose:

The purpose of this funding opportunity announcement (FOA) is to support studies that advance medical product development through the characterization of the natural history of rare diseases/conditions with unmet needs. Through the support of efficient and innovative natural history studies, FDA expects to address critical knowledge gaps, to remove major barrier(s) to progress in the field, to exert a significant and broad impact on a specific rare disease or multiple rare diseases with similar pathophysiology, and to inform current or future product development including the design of clinical trial(s) and to ultimately inform the development of medical products that meet patient needs.