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  5. Public Meeting Exploring the Scope of Dietary Supplement Ingredients - 03/27/2026
  1. Workshops, Meetings & Webinars on Food and Dietary Supplements

Meeting | Mixed

Event Title
Public Meeting Exploring the Scope of Dietary Supplement Ingredients
March 27, 2026

Date:
March 27, 2026

On This Page

Date:
March 27, 2026
Time:
9:00 a.m. – 3:00 p.m. ET
Location:
The public meeting will be available in person or virtually. The in-person meeting will be held at:

Human Foods Program
U.S. Food and Drug Administration
Wiley Auditorium
5001 Campus Drive
College Park, MD 20740

FDA’s Office of Dietary Supplement Programs (ODSP) invites stakeholders to participate in a public meeting to discuss the evolving landscape of dietary supplement ingredients and how recent scientific and technological advances are shaping the industry. During this event, there will be presentations to provide background on the following topics:

  • The scope of the phrase “dietary substance for use by man to supplement the diet by increasing the total dietary intake” as used in DSHEA;
  • New methodologies to produce existing dietary ingredients; and
  • Specific ingredient types, including proteins, enzymes, and microbials.

The meeting will include an opportunity for interested parties to provide oral comment for FDA’s consideration. The FDA will review input received at the public meeting and submitted to www.regulations.gov (docket number FDA-2026-N-2047) to determine next steps. Comments must be submitted on or before April 27, 2026.

Background

The Federal Food, Drug, and Cosmetic Act (FD&C Act) defines “dietary supplement,” in part, as a product that contains one or more dietary ingredients, including “a dietary substance for use by man to supplement the diet by increasing the total dietary intake” (Section 201(ff)(1)(E) of the FD&C Act). ODSP is holding a public meeting to gather stakeholder input regarding the meaning of this provision.

Scientific and technological advancements have led to an increase in development of novel ingredients. For example, new technologies and approaches are being applied to the science of dietary supplements, including precision fermentation, cell culture technology, and recombinant production, which has led to the development of bioactive compounds derived from foods, plants, and other sources. Accordingly, it would be helpful to better understand how these scientific and technical advancements intersect with dietary ingredient production to inform our assessment.

Additionally, the discussion will explore questions related to determining the identity of notable supplement ingredients like proteins, enzymes, and microorganisms, which are not specifically listed in section 201(ff)(1) of the FD&C Act. ODSP is interested in learning about the different attributes that are important for assessing identity.

Submit Comments

Comments on Exploring the Scope of Dietary Supplement Ingredients must be submitted on or before April 27, 2026. Submit electronic comments to www.regulations.gov to docket number FDA-2026-N-2047. Written comments should be sent to Dockets Management Staff (HFA-305), Food and Drug Administration, 5630 Fishers Lane, Room 1061, Rockville, MD 20852. All written comments should identify the docket number FDA-2026-N-2047.

For Further Information

For general questions about the public meeting, please contact the Office of Dietary Supplement Programs at ODSP@fda.hhs.gov.

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