U.S. flag An official website of the United States government
  1. Home
  2. For Federal, State, Local, Tribal, and Territorial Officials
  3. National Integrated Food Safety System (IFSS) Programs and Initiatives
  4. Domestic Mutual Reliance
  1. National Integrated Food Safety System (IFSS) Programs and Initiatives

Domestic Mutual Reliance

Domestic Mutual Reliance (banner image)

Domestic mutual reliance is a seamless partnership that enables the FDA and states with comparable regulatory public health systems, as trusted partners, to rely on, coordinate with, and leverage one another’s work, data, and actions to meet the public health goal of a safe national food supply.

The FDA works with our state partners to build and recognize high quality programs using nationally recognized regulatory program standards like Manufactured Food Regulatory Program Standards (MFRPS) and the Animal Feed Regulatory Program Standards (AFRPS). Such collaboration provides opportunities for the FDA and state partners to lay a quality foundation for sharing information and working together on regulatory services and food protection that industry and consumers can trust.


Partnership Agreements

Map of Domestic Mutual Reliance Partnership Agreements in the USA

[View Original Size Image]

Partnership agreements formally document our domestic mutual reliance relationships  to improve foodborne illness prevention, detection, and response in an Integrated Food Safety System (IFSS). Partners collaborate in the following operational areas to build a highly trained workforce, coordinate food safety inspection efforts, share data, leverage organizational resources, focus on prevention, and better respond to outbreaks. 

  1. Information Sharing and Public Health Protection through Legal Authority
  2. Domestic Mutual Reliance Planning and Evaluation
  3. Leveraging of Resources
  4. Information Technology
  1. Training
  2. Risk-Based Inspection Program
  3. Compliance and Enforcement
  4. Industry and Community Relations
  5. Laboratory Support
  6. Emergency Response


What's New

  • August 2023 – The FDA created an infographic showing the accomplishments from 2017-present of the domestic mutual reliance partnership agreement with the Alaska Department of Environmental Conservation.
  • July 2023 - The FDA worked closely with state regulatory partners in Florida, Iowa, Pennsylvania, Utah, Virginia, and Wisconsin to achieve the major milestone of accepting 1,000 non-contract inspections.  Also known as NCIs, these non-high-risk inspections are conducted by the state under its own authority in which no other regulatory action was required. Similarly, these states have been able to leverage a similar number of FDA inspections to support their oversight activities. NCIs greatly increase efficiency and minimize duplication of efforts for both regulators and industry. These efficiencies enable the FDA and our state regulatory partners to maximize the impact of millions of dollars in state and federal funding, thereby avoiding additional burden to the American taxpayer and enabling regulators to expand coverage and focus limited resources on areas of highest risk to advance food safety for consumers. Learn more about NCIs in this Partnership for Food Protection story.
  • June 2023 - Overview of the Recall Integration Partnership Project 
    This brief video describes the Recall Integration Partnership Project (RIPP), which enhances communication and understanding of FDA/state roles and responsibilities during recall events to more effectively leverage regulatory and enforcement actions that protect public health. Visit the RIPP website today to learn more: https://www.pfp-ifss.org/ripp/


Do you have questions or would you like more information? Please submit them to OP.Feedback@fda.hhs.gov.


Back to Top