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  1. National Integrated Food Safety System (IFSS) Programs and Initiatives

Domestic Mutual Reliance

Domestic Mutual Reliance (banner image)

Domestic mutual reliance is a seamless partnership that enables the FDA and states with comparable regulatory public health systems, as trusted partners, to rely on, coordinate with, and leverage one another’s work, data, and actions to meet the public health goal of a safe national food supply.

The FDA works with our state partners to build and recognize high quality programs using nationally recognized regulatory program standards like Manufactured Food Regulatory Program Standards (MFRPS) and the Animal Feed Regulatory Program Standards (AFRPS). Such collaboration provides opportunities for the FDA and state partners to lay a quality foundation for sharing information and working together on regulatory services and food protection that industry and consumers can trust.


Partnership Agreements

Map of Domestic Mutual Reliance Partnership Agreements in the USA

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Partnership agreements formally document our domestic mutual reliance relationships  to improve foodborne illness prevention, detection, and response in an Integrated Food Safety System (IFSS). Partners collaborate in the following operational areas to build a highly trained workforce, coordinate food safety inspection efforts, share data, leverage organizational resources, focus on prevention, and better respond to outbreaks. 

  1. Information Sharing and Public Health Protection through Legal Authority
  2. Domestic Mutual Reliance Planning and Evaluation
  3. Leveraging of Resources
  4. Information Technology
  1. Training
  2. Risk-Based Inspection Program
  3. Compliance and Enforcement
  4. Industry and Community Relations
  5. Laboratory Support
  6. Emergency Response


What's New

  • May 2023 – The FDA announced the signing of a developmental partnership agreement with the Puerto Rico Department of Consumer Affairs (DACO). The agreement will focus on emergency response, partner training, and minimizing duplicative efforts.
  • March 2023 – The latest Partnership for Food Protection newsletter featured two employees from the FDA’s Office of Regulatory Affairs: Division Director Tim Mueller and Consumer Safety Officer Priscilla Neves. Mueller discussed the ORA Data Exchange and its connection to domestic mutual reliance and an integrated food safety system. Neves discussed how her current role overseeing the domestic mutual reliance project in ORA enables her to collaborate with partners to advance food safety.  
  • February 2023 – The FDA signed a domestic mutual reliance partnership agreement with the New York Department of Agriculture and Markets. New York takes an innovative approach to collaborate on food safety for domestically produced foods, imported foods, and laboratory testing in conjunction with the FDA. This ORA News and Stories article details the agreement.


Do you have questions or would you like more information? Please submit them to OP.Feedback@fda.hhs.gov.


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