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  1. National Integrated Food Safety System (IFSS) Programs and Initiatives

Domestic Mutual Reliance

Domestic Mutual Reliance (banner image)

Domestic mutual reliance is a seamless partnership that enables FDA and states with comparable regulatory public health systems, as trusted partners, to rely on, coordinate with, and leverage one another’s work, data, and actions to meet the public health goal of a safe national food supply.

The FDA works with our state partners to build and recognize high quality programs using nationally recognized regulatory program standards like Manufactured Food Regulatory Program Standards (MFRPS) and the Animal Feed Regulatory Program Standards (AFRPS). Such collaboration provides opportunities for the FDA and state partners to lay a quality foundation for sharing information and working together on regulatory services and food protection that industry and consumers can trust. 


Partnership Agreements

Map of Domestic Mutual Reliance Partnership Agreements in the USA

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Types of Partnership Agreements

  • Domestic Mutual Reliance partnership agreements capture existing and new engagements focused on advancing collaborative activities in all areas of prevention, detection, and response. California, Florida, IowaMinnesota, Utah, Virginia, Wisconsin
  • Developmental partnership agreements advance the initial development of a domestic mutual reliance collaborative relationship. Hawaii
  • Specialized partnership agreements focus on a specific collaborative activity. Alaska, Rhode Island 

Partnership agreements help us to work toward an Integrated Food Safety System (IFSS). Partners can build a highly trained workforce, coordinate food safety inspection efforts, share data, leverage resources, focus on prevention and better respond to outbreaks. This collaboration includes:

  • Data exchange/information sharing
  • Work planning and risk prioritization/categorization, including inspection frequency mandates, and comparison and reconciliation of inventories
  • Inspection, compliance/enforcement, and corrective actions
  • Environmental assessment
  • Recall oversight and effectiveness/audit checks
  • Investigation of outbreaks and complaints
  • Sample collection and laboratory capacity, analysis, and reporting
  • Field staff training
  • Industry and consumer education
  • Organizational resources and personnel
  • Development and monitoring of key domestic mutual reliance metrics


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Do you have questions or would you like more information? Please submit them to OP.Feedback@fda.hhs.gov.


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