Fluconazole Injection, Oral
Exceptions to the Recognized Standard
|
Minimum Inhibitory |
Disk Diffusion Disk Diffusion at 24 Hours |
||||
---|---|---|---|---|---|---|
Pathogena |
S |
Ic |
R |
S |
Ic |
R |
Candida albicans |
M27M44Sb |
4 |
M27M44Sb |
M27M44Sb |
14-16 |
M27M44Sb |
Candida glabrata |
M27M44Sb |
< 32 |
M27M44Sb |
M27M44Sb |
>15 |
M27M44Sb |
Candida parapsilosis |
M27M44Sb |
4 |
M27M44Sb |
M27M44Sb |
14-16 |
M27M44Sb |
Candida tropicalis |
M27M44Sb |
4 |
M27M44Sb |
M27M44Sb |
14-16 |
M27M44Sb |
S = Susceptible; I = Intermediate; R = Resistant
a Isolates of C. krusei are assumed to be intrinsically resistant to fluconazole and their MICs and/or zone diameters should not be interpreted using this scale.
b M27M44S standard is recognized.
c The term “SDD” is not recognized pending further clarification of the definition of the term by standards development organizations. For isolates testing “I”, doses higher than 6 mg/kg/day should be considered.