Hiranthi Jayasuriya PhD.

Division of Residue Chemistry

Biography

Dr. Hiranthi Jayasuriya is a research chemist with the Division of Residue Chemistry in the Office of Applied Science at FDA’s Center for Veterinary Medicine. In 1998, she received her PhD in natural products chemistry from the University of Mississippi. She joined FDA as a research chemist in 2008 after working as a senior scientist at Merck Research Laboratories in natural products drug discovery for 16 years. Her primary responsibilities at CVM include conducting and coordinating research in analytical method development for residue analysis in animal tissue and feed.

Research

Development of high-resolution mass spectrometric (HRMS) methods for residue analysis
Untargeted analysis by HRMS
Development of HRMS guidances

Select Publications

Lauren Girard, Kithsiri Herath, Hernando Escobar, Renate Reimschuessel, Olgica Ceric and Hiranthi Jayasuriya, “Development of UHPLC/Q-TOF Analysis Method to Screen Glycerin for Direct Detection of Process Contaminants 3-Monochloropropane-1,2-diol Esters (3-MCPDEs) and Glycidyl Esters (GEs)” Molecules 2021, 26, 2449. https://doi.org/10.3390/molecules 26092449

Turnipseed, S and Jayasuriya, H. “Analytical methods for mixed organic chemical residues and contaminants in food” Analytical and Bioanalytical Chemistry (2020) at https://doi.org/10.1007/s00216-020-02668-8

Jayasuriya, H., Li, H., Turnipseed, S., Crowley, T., Gamble, B., Wong, J., 2016. “Acceptance Criteria for Confirmation of Identity of Chemical Residues Using Exact Mass Data Within the Office of Foods and Veterinary Medicine." Available at https://www.fda.gov/science-research/field-science-and-laboratories/method-validation-guidelines

Herath, K., Girard, L., Reimschuessel, R., and Jayasuriya, H., 2017. Application of time-of-flight mass spectrometry for screening of crude glycerins for phorbol ester contaminants. Journal of Chromatography B, 1046, pp. 226–234.

Nishshanka, U., Jayasuriya, H., Chattopadhaya, C., Kijak, P.J., Chu, P.S., Reimschuessel, R., Tkachenko, A., Ceric, O. and De Alwis, H.G., 2016. Screening for toxic phorbol esters in jerky pet treat products using LC–MS. Journal of Chromatography B, 1020, pp. 90–95.

Nishshanka, U., Chu, P.S., Evans, E., Reimschuessel, R., Hasbrouck, N., Amarasinghe, K. and Jayasuriya, H., 2015. Tentative structural assignment of a glucuronide metabolite of methyltestosterone in tilapia bile by liquid chromatography–quadrupole-time-of-flight mass spectrometry. Journal of Agricultural and Food Chemistry, 63(24), pp. 5753–5760.

Amarasinghe, K., Chu, P.S., Evans, E., Reimschuessel, R., Hasbrouck, N., and Jayasuriya, H., 2012. Development of a fast screening and confirmatory method by liquid chromatography–quadrupole-time-of-flight mass spectrometry for glucuronide-conjugated methyltestosterone metabolite in tilapia. Journal of Agricultural and Food Chemistry, 60(20), pp. 5084–5088.

Contact Information: Hiranthi Jayasuriya; +1 (240) 402-6688