Science & Research

Accessing EDKB Database

You will notice some delay the first time you run EDKB because the entire EDKB application must download the first time you access it. Because future uses of the software will only download any parts of the application that have been changed, the application should start much quicker. You may also be prompted to update your version of Java before EDKB will run. *Note: Use this link to install or re-install Java. 

Register for Software Updates and Notifications 

OPTION 1:  Launch EDKB

OPTION 2:  Download the EDKB zip file (32 MB)    

  • Get download instructions 

  • Please contact if you need assistance with accessing any documents contained inside the zip file.

Possible Error Messages

  • "Connection failed: the network adapter could not establish the connection..."

This might be due to your organization's firewall. Many firewalls are set up to only allow traffic to destination port 80 on remote hosts (Web traffic). However, the EDKB server needs to be contacted on port 1610. Thus, you need to contact your system administrator about this particular port number (port 1610) that may need to be opened as an allowed destination port for outgoing connections on your organization's firewall. 

The following statement has been prepared for your convenience to communicate with your system administrator: 
"The EDKB server is listening on port 1610 for connections from the EDKB client software. An organization whose hosts are to run the EDKB client software needs to allow outgoing connections from any port (source port is randomly chosen on the client as is usual with Internet communications), to the fixed destination port of 1610 on"

  • "Couldn't load jnlp file to..."

Follow the steps below to fix the problem: 

  1. Open the "Tools" menu of your Internet browser and select "Internet Options.
  2. "Select the "General" tab and click the "Settings" button in the "Temporary Internet Files" section.
  3. Select the "Every visit to the page" radio button.
  4. Click "OK."
    Note:  If you still receive the error message after following the steps above, repeat Steps 1 and 2, click the "Delete Files" button instead of the "Settings" button in Step 2 and click OK.
Contact Information

Please address any questions and suggestions to Dr. Weida Tong at 870-543-7142 or

EDKB is a product designed and produced by the National Center for Toxicological Research (NCTR).  FDA and NCTR retain ownership of this product.


Contact FDA

National Center for Toxicological Research

Food and Drug Administration

3900 NCTR Road

Jefferson, AR 72079

Page Last Updated: 03/12/2018
Note: If you need help accessing information in different file formats, see Instructions for Downloading Viewers and Players.
Language Assistance Available: Español | 繁體中文 | Tiếng Việt | 한국어 | Tagalog | Русский | العربية | Kreyòl Ayisyen | Français | Polski | Português | Italiano | Deutsch | 日本語 | فارسی | English