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U.S. Department of Health and Human Services


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Zantac 25/150 (ranitidine hydrochloride) EFFERdose Tablets and 150 (ranitidine hydrochloride effervescent) Granules February 2009


  • Drug Interactions
    • Inhibition....
    • Competition....
    • Alteration....
  • Midazolam
    • ...in another interaction study in 8 volunteers receiving IV midazolam, a 300 mg oral dose of ranitidine increased midazolam exposure by about 9%. Monitor patients for excessive or prolonged sedation when ranitidine is coadministered with oral midazolam


  • Other
    • the addition of "acute interstitial nephritis".



The latest label (approved 02/17/2009) is not available on this site