Sleep Disorder (Sedative-Hypnotic) Drug Information

Sedative-hypnotic drug products are a class of drugs used to induce and/or maintain sleep.

FDA Drug Safety Communications:

• FDA warns of next-day impairment with sleep aid Lunesta (eszopiclone) and lowers recommended dose (5/15/2014)
• FDA approves new label changes and dosing for zolpidem products and a recommendation to avoid driving the day after using Ambien CR (5/14/2013)
• Risk of next-morning impairment after use of insomnia drugs; FDA requires lower recommended doses for certain drugs containing zolpidem (Ambien, Ambien CR, Edluar, and Zolpimist) (1/10/2013)

Prescription Insomnia Drugs

For prescribing information, please search the Drugs@FDA database.

• Ambien (zolpidem)
• Belsomra (suvorexant)
• Butisol (butabarbital)
• Doral (quazepam)
• Edluar (zolpidem)
• Estazolam
• Flurazepam
• Halcion (triazolam)
• Hetlioz (tasimelteon)
• Intermezzo (zolpidem)
• Lunesta (eszopiclone)
• Restoril (temazepam)
• Rozerem (ramelteon)
• Seconal (secobarbital)
• Silenor (doxepin)
• Sonata (zaleplon)
• Zolpimist (zolpidem)

Over-the-counter (OTC) Insomnia Drugs

• Benadryl (diphenhydramine)*
• Unisom (doxylamine)*

*Also in many cold and headache combination products