Drug Development and Drug Interactions: Possible Models for Decision-Making

Drug Development and Drug Interactions: Possible Models for Decision-Making

• Possible Model for Decision Making: Metabolism-Based Drug-Drug Interaction Studies (Figures 1-4).
• Possible Model for Decision Making: Transporter-Based Drug-Drug Interaction Studies (Figure 5)
• Possible Models for Determining When In Vivo Transporter-Mediated Drug Interaction Studies Are Needed (Figures 6-11)
• Possible Model for Decision Making: Therapeutic Protein-Drug Interactions (Figure 12).