|2005P-0267|| Remove from label for propofol (Diprivan) the warning that propofol should be administered only by trained persons|
|FDA Comment Number :||EC165|
|Submitter :||Dr. Ali Afrassiabi||Date & Time:||11/17/2005 01:11:20|
|Organization :||Dr. Ali Afrassiabi|
|Category :||Health Professional|
| I use propofal every day. Frequently this use is in very small doses, to allow the injection of a local anesthetic. Although dosing suggestions are made by the manufacturer, every single patient seem to have a different response and dose requirement. Many people become apenic and desaturate rapidly, i.e are under a general anesthtetic, even with a dose of Propofal that is well below the recommended dose by the manufacturer to achieve induction of a general anesthetic. This is a situation that can be extremely dangerous if the person adminitering Propofal is not fully trained in genral anestheisa and advanced Airway Mangement. I urge the FDA to continue its policy of limiting the use of Propofal to professionals trained in General Anesthesia.
Ali Afrassiabi, MD
Gig Harbor, WA