04N-0081
C 114
Volume 14

Comment

Appendix 1

Grobben, Adrianus H., Phillip J. Steele, Robert A. Somerville, David M. Taylor. Inactivation of the bovine spongiform encephalopathy (BSE) agent by the acid and alkaline processes for manufacturing of bone gelatine, Biotechnol Appl Biochem 39 (2004) 320-338

Validation of the clearance of TSE agent by the heat and pressure process for manufacturing of gelatine and colloidal protein

Validation of the clearance of TSE agent by the acid bone gelatine manufacturing process

Validation of the clearance of TSE agent by the initial steps of the alkaline gelatine manufacturing process

Validation of the clearance of TSE agent by the alkaline gelatine manufacturing process

Validation of the clearance of TSE infectivity by the initial steps of the acid bone gelatine manufacturing process with an additional short NaOH treatment

Gelatine Manufacturers of Europe (GME). The Removal and Inactivation of Potential TSE Infectivity by the Different Gelatin Manufacturing Processes, June 2003

Appendix 2

http://www.oie.int/eng/Normes/mcode/en_chapitre_2.3.13.htm