From: Gary Krasner [gk-cfic@juno.com] Sent: Saturday, June 22, 2002 12:33 AM To: fdadockets@oc.fda.gov Cc: bullelkman@aol.com; skreider@dca.net Subject: comment re: Docket No. 01N-0067 Comment submitted by Gary Krasner, Director, Coalition For Informed Choice. 188-34 87th Drive, #4B, Hollis, NY 11423 Fax / Phone: 718-479-2939, email: GK-CFIC@JUNO.COM re: Docket No. 01N-0067 Dear FDA, As a health activist for 30 years, I’ve encountered dozens of people inflicted with the effects of mercury toxicilty. Many have restored their health only by removal of their amalgam fillings. Upon removal, dentists must treat the fillings as a toxic waste substance. This goes to the issue of stability while in the mouth. There are numerous studies that indicate 50% mercury fillings leach mercury into the body through various routes. Beyond the vast accumulated annectodal evidence, I urge you to review the medical literature supplied by dedicated anti-amalgam organizations to support more restrictions on the application of this substance for dental carries. I offer one such study below: Amalgam Fillings May Damage Kidneys Amalgam fillings and skin- lightening creams both contain significant amounts of mercury. Researchers at the King Faisal Hospital in Riyadh, Saudi Arabia have just completed a study aimed at determining whether the mercury actually gets into the blood stream. The study involved 225 women (aged 17 to 58 years) who had their urine measured for mercury, creatinine, urea, uric acid, phosphorus, magnesium, calcium, and glucose. The urinary mercury level varied between 0 and 204.8 micrograms per liter and was directly related to the number of dental amalgam fillings present in the women's mouths. The researchers conclude that chronic exposure to mercury may be associated with deterioration of renal (kidney) function. Source: Biometals, Vol. 10, October 1997, pp. 315-23