From: nagreenegrove@juno.com Sent: Tuesday, April 03, 2001 10:32 PM To: fdadockets@oc.fda.gov Subject: Docket 00N-1396 and Docket 00D-1598 Docket Clerk: I am opposed to genetically modified plants and animals without mandatory pre-market safety testing, pre-market environmental review, and mandatory labeling. Voluntary labeling of non-genetically engineered foods should not be restricted. The FDA has failed to ensure public access to adequate information for independent review. FDA must require mandatory pre-market comprehensive environmental review. unlike conventional pollutants, wehre a given amount of pollutant causes a limited amount of damage, a small number of mutant genes could have a population explosion and reproduce forever, causing unlimited irreparagle damage. FDA must require mandatory pre-market long-term health testing. Genetically engineered products could be toxic, cuase allergic responses, have lower nutritional value, and compromise immune responses in consumers. FDA must require mandatory labelinf of genetically engineered products. Without mandatory labeling, neither consumers nor health professionals will know if an allergic or toxic reaction was the result of a genetically engineered food. consumers would be deprived of the critical knowledge they need to hold producers liable should any of these new products be hazardous. FDA must end its cozy relationship with industries it should be regulating. I am told that people have been allowed to work for a biotech company, then work for FDA writing the regulatory rules on tht company's product, then go back to working for the company. I am told that 92% of FDA advisory committee meetings had at least one conflict of interest. We are looking to the FDA to ensure the health and safety of our food and agricultural products. Please do not let us and our children and grandchildren down. Nancy Greene