From: OC EXECSEC Sent: Friday, June 08, 2001 2:50 PM To: Dockets, FDA Subject: FW: Do Not Approve A/F Protein's Genetically Engineered Fish--Docket# 01P-0230 -----Original Message----- From: Maeve Hilleary [mailto:rainee-day@home.com] Sent: Friday, June 08, 2001 1:03 PM To: Commissioner Subject: Do Not Approve A/F Protein's Genetically Engineered Fish--Docket# 01P-0230 Commissioner , I am contacting you to express my outrage and concern about the possible commercialization of genetically engineered fish. I urge the FDA not to approve the current application by A/F Protein to sell GE Salmon. Genetically engineered fish have the potential to be invasive species that could cause irreversible ecological damage to wild fish stocks as well as the wider marine environment. Sterility of genetically engineered fish is inherently uncertain given the possibility for human error and natural variation. Even if sterility were ever achievable, sterile genetically engineered fish would still compete with wild fish for food, habitat and will effect the overall marine ecology. The history of fish farming clearly demonstrates that once released into ocean ponds, fish will escape and, since fish do not obey national boundaries, any release of genetically engineered fish will be international by its very nature. The release of GE fish is an international concern in which we all have a stake and on which every government and their citizens should have an opportunity to say no. I urge the FDA not to approve the current application by A/F Protein for GE Salmon because GE fish pose an unnecessary and unacceptable risk to the marine environment and potentially to human health. The impact of genetically engineered animals and crops to human health has not been tested or determined, and until it is guaranteed not to harm the environment, marine life, or human life, these products must not be approved for release or consumption. Maeve Hilleary 2627 S. Lewiston St. Aurora, CO 80013-1404 USA rainee-day@home.com