From: LeRoy W. Haynes [haynes@acs.wooster.edu] Sent: Tuesday, January 09, 2001 5:23 PM To: EXECSEC Subject: antibiotics in agriculture Jane E. Henney, M.D. Commissioner U. S. Food and Drug Administration 5600 Fishers Lane Rockville MD 20857-0001 Dear Commissioner Henney, An alert from the Union of Concerned Scientists concerning the use of antibiotics in agriculture and my own readings in the area prompt me to send this message. I urge you to take whatever steps are necessary to evaluate the use of antibiotics in agriculture. That could include, but not be limited to, monitoring how much and what antibiotics are used, with what animals, how the animal wastes are handled so that the residual antibiotics and their metabolites don't make their way into ground or surface water, and the levels of antibiotics and their metabolites in food products. The use of anything that can reduce the potency of antibiotics used to treat human diseases should be minimized. Just recently I learned that the wife of my cousin, who has battled cancer of the lymph glands for a couple of decades, has a very serious diarrhea problem caused by an intestinal bacterial infection. She is currently taking what her doctor describes as the "antibiotic of last resort". I realize that her situation is on the dramatic side since she's been subjected to the side effects of chemotherapy. However, I would not want to see people with less serious infections restricted to the number of effective antibiotics available to their physicians. Sincerely, -- LeRoy W. Haynes Professor of Chemistry Emeritus The College of Wooster Wooster, OH 44691 330-263-2012 haynes@acs.wooster.edu "You may have to fight a battle more than once to win it." Margaret Thatcher