From: Sent: Tuesday, December 05, 2000 5:27 PM To: fdadockets@oc.fda.gov Subject: lotronex I was very upset when the FDA with drawled lotronex from the market. I understand that there was some problems with the medicine, and many complaints from people who do not even have IBS. Well i have IBS and for 7 years I have felt trapped in my own home I was afraid to leave for I never know when I would have to go to the bathroom. I started taking lotronex and I was able to enjoy life again. I had no problems with the medicine and was made aware of what to do if I did have problems to stop taking the medicine. I truly believe that this medicine is needed and that you should make it available for those who can benefit from it. Thank you for your time,