Trends in risk assessment

2/15/00


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Table of Contents

Trends in risk assessment

Potential utility of biomarkers to discovery and development of new pharmaceuticals

Potential utility of biomarkers to risk assessment

A conceptual view of biomarkers

Source of materials and methodologies for assessment of biomarkers

Biomarkers of hazard: specific examples

Products of altered gene and protein expression

Biomarkers: extrapolation between animals and man

Biomarkers: cross species extrapolation

PPT Slide

Biomarkers: cross species extrapolation for risk assessment

Biomarkers: application to risk assessment

Biomarkers: application to risk assessment

Biomarkers of effects induced by Thiazolidinediones

Plasma von Willebrand factor rats given 60 mg/kg SKF-82526

Heart weight in different models of cardiac hypertrophy

LV-cTnT concentration in difference models of cardiac hypertrophy

Author: ANITA B WINNER