5-FU/LV vs. 5-FU Randomized Trials in Metastatic Colorectal Cancer

Author

Year

N

Median Survival (mos)

p-value

Meta-analysis Group

(9 trials)

1,381

11.5 vs. 11.0

ns

Poon (HDLV)

1989

138

12.2 vs. 7.7

0.04

Poon (LDLV)

1989

140

12.0 vs. 7.7

0.05

Bobbio-Pallavicini

1993

150

8.0 vs. 6.0

?.05

Petrioli

1995

234

13.5 vs. 7.5

0.04

Borner

1998

310

12.4 vs. 10.0

0.02

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