Renal Transplantation: Present Status

8/18/99


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Table of Contents

PPT Slide

Renal Transplantation: Present Status

Renal Transplantation: Challenges for the Future

Mechanism of Action

RAPAMUNE

Action of RAPAMUNE Is Different From Other Immunosuppressive Agents

mTOR Is a Critical Kinase in Cell Cycle Progression

RAPAMUNE Is Effective in Animal Transplant Models

RAPAMUNE Prolongs Survival of Pig Renal Allografts

RAPAMUNE and Cyclosporine Are Synergistic in Rat Heart Allograft Model

No Renal Toxicity in Preclinical Studies

RAPAMUNE Summary of Animal Models

Author: Maureen Galie