Efficacy Without SedationProtocols 006 and 008 CombinedClinical Global Impression of Change - Visit 2

55

65

75

85

95

No

Sedation

All

Patients

With

Sedation

No

Sedation

All

Patients

With

Sedation

Percentage of Responders

CYC 5 mg

Placebo

(N=321)

(N=453)

(N=132)

(N=413)

(N=458)

(N=45)

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